CAS: 4101-30-8; 1-(2-Amino-4,5-Dimethoxyphenyl)Ethanone

上下游产品

1-(4,5-二甲氧基-2-硝基苯基)乙酮 4',5'-Dimethoxy-2'-Nitroacetophenone 4101-32-0
3,4-二甲氧基苯乙酮 1-(3,4-Dimethoxyphenyl)Ethanone 1131-62-0
2-氨基-4,5-二甲氧基苯腈 2-Amino-4,5-Dimethoxybenzonitrile 26961-27-3

1-(4,5-二甲氧基-2-硝基苯基)乙酮置于hydrazine Hydrate,Femo1.1S3.2体系中,用 乙醇 作为反应溶剂,30.0 °C,100.0 Kpa 条件下,反应 2.0H,反应生成 2'-氨基-4',5'-二甲氧基苯乙酮
参考文献:[femo]Sx 催化剂上极性氢物种介导硝基芳烃选择性还原为苯胺
标题:[femo]Sx 催化剂上极性氢物种介导硝基芳烃选择性还原为苯胺
摘要:我们在此提出了一种在铁-钼硫化物催化剂 ([femo]S X)上从硝基芳烃和肼化学选择性合成芳胺的有效方法.非均相氢转移还原可以在 30 oc 下有效地进行,并提供具有 95-99% 选择性的苯胺.原位气体产物分析表明,[femo]S X可以催化 N 2 H 4分解为 H* 物质,而不是 H 2. 结合硝基苯和中间体苯胺反应生成速率的动力学分析,确定硝基还原为亚硝基是速率决定步骤.hammett 方程的正斜率表明速率决定步骤中的关键中间体处于负状态,这表明活性 H* 应该处于极性状态(h δ-和 H δ+).这些发现将为取代苯胺的合成提供一条新途径,并拓宽mos X催化剂在温和条件下的应用.
DOI:10.1039/d1Dt03107D

专利信息

专利号:US-4490374-A
优先权日:1982-09-30
标 题:5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use
发明人：BANDURCO VICTOR T; LEVINE SEYMOUR D; MULVEY DENNIS M; TOBIA ALFONSO J
权利人:ORTHO PHARMA CORP
摘要:The synthesis of substituted quinazolinones is described. The novel quinazolinones are renal vasodilators and thereby increase renal blood flow, and are useful as cardiovascular agents.

专利号:US-5112866-A
优先权日:1988-09-06
标题:Ethanesulfonamide derivatives
发明人：RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of novel ethanesulfonamide compounds is described. The novel ethanesulfonamide compounds have antisecretory activity and are used in the treatment of peptic ulcer disease. The intermediates used to prepare the ethanesulfonamides are useful in the treatment of osteoporosis and other bone wasting diseases.

专利号:US-4631283-A
优先权日:1982-09-30
标 题:Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids
发明人：BANDURCO VICTOR T; LEVINE SEYMOUR D; MULVEY DENNIS M; TOBIA ALFONSO J
权利人:ORTHO PHARMA CORP
摘要:The synthesis of substituted quinazolinones is described. The novel quinazolinones are renal vasodilators and thereby increase renal blood flow, and are useful as cardiovascular agents.