CAS: 257928-43-1; (R)-4-(4-(Benzyloxy)Phenyl)-1-(1-Phenylethyl)-1,2,3,6-Tetrahydropyridine
该化合物是一种复杂的有机化合物,其特征是双环结构,包括一个环和一个四氢配置.该化合物具有苯乙基替代成分,表明乙基链中存在一个有助于其疏水特性的联苯组.此外,一个苯氧基组的存在增加了其与其他有机分子互动的潜力,使其对各种化学应用,包括制药和有机合成感兴趣. (1R) 称的立体化学学表明,可影响该化合物的再活动性和生物活动的具体空间安排.
- 英文名称(R)-4-(4-(Benzyloxy)Phenyl)-1-(1-Phenylethyl)-1,2,3,6-Tetrahydropyridine
- 中文名称1,2,3,6-四氢-1-[(1R)-1-苯基乙基]-4-[4-(苯基甲氧基)苯基]吡啶
- IUPAC名称(R)-4-(4-(benzyloxy)phenyl)-1-(1-phenylethyl)-1,2,3,6-tetrahydropyridine
- 其它别名(R)-4-(4-(Benzyloxy)Phenyl)-1-(1-Phenylethyl)-1,2,3,6-Tetrahydropyridine; 1,2,3,6-Tetrahydro-1-[(1R)-1-Phenylethyl]-4-[4-(Phenylmethoxy)Phenyl]Pyridine; 4-(4-Benzyloxy-Phenyl)-1-(1-Phenyl-Ethyl)-1,2,3,6-Tetrahydro-Pyridine; Pyridine, 1,2,3,6-Tetrahydro-1-[(1R)-1-Phenylethyl]-4-[4-(Phenylmethoxy)Phenyl]-; 1-[(1R)-1-Phenylethyl]-4-(4-Phenylmethoxyphenyl)-3,6-Dihydro-2H-Pyridine
- CAS编号257928-43-1
- MFCD编号:MFCD13689120
- 分子式:C26H27NO分子量:369.51
- 产品CID: 1222580
- 产品分类医药中间体 → 吡啶类化合物
MSDS等安全信息
上下游产品
CAS号50-00-0 甲醛 | CAS号3886-69-9 R(+)-alpha-甲基苄胺 | CAS号257938-67-3 N-叔丁氧羰基-4-(4-羟基...合成工艺路线路线简述
📜(R)-4-(4-Benzyloxy-Phenyl)-1-(1-Phenyl-Ethyl) Piperidin-4-Ol,1,2,3,4-四氢吡啶,Oxalic Acid Dihydrate置于sodium Hydroxide体系中,用 甲醇,1,1-二氯乙烷,二氯甲烷,水,乙酸乙酯 用作溶剂,化学反应生成1,2,3,6-四氢-1-[(1R)-1-苯基乙基]-4-[4-(苯基甲氧基)苯基]吡啶
参考文献:Process And Intermediates For Preparation Of Substituted Piperidine-Epoxides
标题:Process And Intermediates For Preparation Of Substituted Piperidine-Epoxides
摘要:本发明涉及用于制备公式1化合物或其盐的有用中间体及制备过程,包括对公式2化合物或其盐进行环氧化,其中a,R1和r2如本文所定义.这些化合物在肾素抑制剂合成中是有用的.
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902500000-苯乙烯
2902600000-乙苯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6268499-B1
优先权日:1998-08-10
标 题 :Process and intermediates for preparation of substituted piperidine-epoxides
发明人：GUELLER ROLF; LOHRI BRUNO; SCHMID RUDOLF
权利人:HOFFMANN LA ROCHE
摘要:The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof n comprisingepoxidation of a compound of formula 2 or a salt thereof n wherein A, R 1 and R 2 are as herein defined. These compounds are useful in the synthesis of renin inhibitors.
专利号:US-6274735-B1
优先权日:1998-08-10
标 题 :Process and intermediates for preparation of substituted piperidines
发明人：LOHRI BRUNO; SCHMID RUDOLF; VIEIRA ERIC
权利人:HOFFMANN LA ROCHE
摘要:The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof n comprising n a) hydroboration of a compound of formula 2 n A, R 1 and R 2 are as herein defined. These compounds are useful in the synthesis of renin inhibitors.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Process And Intermediates For Preparation Of Substituted Piperidines摘要:The Present Invention Concerns Intermediates Useful In And A Process For The Preparation Of A Compound Of Formula 1 Or A Salt Thereof Comprising A) Hydroboration Of A Compound Of Formula 2 A, R1 And R2 Are As Herein Defined. These Compounds Are Useful In The Synthesis Of Renin Inhibitors.
合成参考文献
参考DOI号:10.1016/S0014-827X(01)01004-7
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