CAS: 24502-78-1; (R)-1-(5,8-Dihydroxy-1,4-Dioxo-1,4-Dihydronaphthalen-2-yl)-4-Methylpent-3-En-1-Yl Acetate
该化合物是一种天然的化合物,被归类为环烷磺酮衍生物,主要来自Lithospermum 红红血素松植物(俗称紫红葡萄树)的根部,其特点是独特的化学结构,包括一个带有各种功能组的环环环纳米系统,有助于其生物活动;Acetylshikonin展示了多种药理特性,包括防炎,抗微生物和抗氧化活动,使其对医药化学和天然产品研究感兴趣;该化合物经常被研究其潜在的治疗用途,特别是创伤愈合和皮肤再生,该化合物通常在有机溶剂中溶解,其稳定性可能受到诸如pH和光接触等因素的影响;此外,乙酰锡辛的生物活性可归因于其调控各种细胞路径的能力,这促使对其治疗各种疾病的行动和潜在用途机制进行调查.总体而言,乙基锡康宁是天然产品领域的一个重要化合物,在健康和医学领域有希望的应用.
- 英文名称(R)-1-(5,8-Dihydroxy-1,4-Dioxo-1,4-Dihydronaphthalen-2-yl)-4-Methylpent-3-En-1-Yl Acetate
- 中文名称乙酰紫草素
- IUPAC名称(R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl acetate
- 其它别名Shikonin, Acetyl; Acetylshikonin; Acetyl Shikonin; 1-(5,8-Dihydroxy-1,4-Dioxo-1,4-Dihydro-2-Naphthalenyl)-4-Methyl-3-Pentenyl Acetate #; (R)-1-(5,8-Dihydroxy-1,4-Dioxo-1,4-Dihydronapht
- CAS编号24502-78-1
- MFCD编号:MFCD00143538
- FDA UNII编号:ST04094S3X
- 分子式:C18H18O6分子量:330.34
- 产品CID: 1193134
- 产品分类化学试剂 → 有机试剂 → 双环化合物
物理性质
MSDS等安全信息
上下游产品
CAS号517-89-5 紫草素 | CAS号64-19-7 冰醋酸 | CAS号108-24-7 乙酸酐 | CAS号517-89-5 紫草素 | CAS号77386-93-7 naphthazarin-di... | CAS号80186-91-0 cycloalkannin l...合成工艺路线路线简述
📜紫草素,溶剂黄146置于4-二甲氨基吡啶,N,N'-二环己基碳二亚胺体系中,用 二氯甲烷 用作溶剂,以83%的收率获得乙酰紫草素
参考文献:氟酰基紫草素抗癌剂的设计与合成
标题:氟酰基紫草素抗癌剂的设计与合成
摘要:合成了一系列在紫草素侧链上被各种氟化羧酸选择性酰化的紫草素衍生物,并对其抗癌活性进行了评估,其中首次报道了八种化合物.在所有测试的化合物中,化合物s7对b16-F10(恶性黑色素瘤细胞),Mg63(人骨肉瘤细胞)和a549(肺癌细胞)显示出最有效的抗癌活性,Ic 50为0.39+/-0.01,0.72+/-0.04和0.58 +/-0.02 µmol / L.进行化合物s7的对接模拟以将s7定位在微管蛋白活性位点,以确定可能的结合构象.所有结果表明,化合物s7可能是潜在的抗癌药.手性25:757-762,2013.©2013 Wiley Periodicals,Inc.
Doi:10.1002/chir.22209
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2905122000-异丙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2023203374-A1
优先权日:2022-04-20
标 题 :[1,2]selenazolo[2,3-a]pyridin-8-ium inhibitors of pyruvate kinase isoform m2
发明人：ARSENJANS PAVELS; DIMITRIJEVS PAVELS; MAKRECKA-KUKA MARINA
权利人:LATVIAN INST ORGANIC SYNTHESIS
摘要:The present invention relates to a novel isoselenazolopyridinium salts as anticancer agents by inhibiting pyruvate kinase isoform M2 (PKM2) activity, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment of various diseases and disorders by administration of such substances.
专利号:US-2019314312-A1
优先权日:2016-07-11
标题 :Combination therapy to increase endogenous nitric oxide (no) synthesis
发明人：EREZ AYELET; STETTNER NOA
权利人:YEDA RES & DEV
摘要:Provided are uses of a therapeutically effective amount of citrulline for the manufacture of a medicament for treatment of a subject having an inflammatory bowel disease (IBD) and/or colon cancer. Also provided are pharmaceutical compositions comprising a therapeutic effective amount of citrulline and a therapeutically effective amount of a flavonoid for the treatment of an inflammatory bowel disease (IBD) and/or colon cancer and kits comprising same.
专利号:KR-102686376-B1
优先权日:2022-09-01
标 题 :Carbon quantum dots based on by-products of gromwell root and a method for synthesis of carbon quantum dots based on by-products of gromwell root
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology., 73(193), 1977 []
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