CAS: 1599-47-9; 1,1-Dimethoxyhexane

该化合物是一种具有分子式C8H18O2的直角氧烷化合物,由于酸性条件下的稳定性和反应性,它通常用作有机合成的溶剂和中间剂.该化合物的结构由两个与六氟基相连的甲氧基组组成,有助于保护合成应用中的碳基组.其相对较低的挥发性和疏水特性增强了其适应需要控制条件的专门反应的能力.此外,1,1-二甲基氧氧氧烷与一系列试剂的兼容性,有助于其在精细化学和制药工艺中的多用途性. 适当的处理应该遵循易燃有机化合物的标准安全协议.

英文名称1,1-Dimethoxyhexane
中文名称1,1-二甲氧基己烷
IUPAC名称1,1-dimethoxyhexane
其它别名hexaldehyde dimethyl acetal; hexanal dimethyl acetal; 1,1-dimethoxyhexane; hexane, 1,1-dimethoxy-; n-hexanal dimethylacetal, 98+%; n-hexanal dimethylacetal
CAS编号1599-47-9
MFCD编号:MFCD00036508
EINECS号:216-488-5
FDA UNII编号:C2N95Z7EA9
分子式:C8H18O2分子量:146.23
产品CID: 802642
产品分类有机原料→分子砌块→脂肪链类化合物

相似结构搜索
InChIKey: ZQUJUCJLDXTKKW-UHFFFAOYSA-N
InChI=1S/C8H18O2/c1-4-5-6-7-8(9-2)10-3/h8H,4-7H2,1-3H3
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数6.0

相似化合物

7779-41-1 18824-63-0 10022-28-3

MSDS等安全信息

GHS象形图
GHS符号GHS02 & GHS07;
注释: Flame & Exclamation mark
危险类别易燃液体类别3
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Warning(警告)
危险描述H226 |易燃液体和蒸气.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P210-P240-P241-P242-P243-P261-P264-P271-P280-P304+P340-P363-P370+P378-P501
危险等级3
UN编号3271.0
危险品标志Xi
包装等级Ⅲ
安全声明26-36
危险类别码10-36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

📜丙烯醛二甲缩醛置于palladium On Activated Charcoal 甲酸,三乙胺体系中,化学反应 68.0H,反应生成己醛而甲基乙缩醛
参考文献:Palladium-Catalyzed Triethylammonium Formate Reductions. 4. Reduction Of Acetylenes To Cis-Monoenes And Hydrogenolysis Of Tertiary Allylic Amines
标题:Palladium-Catalyzed Triethylammonium Formate Reductions. 4. Reduction Of Acetylenes To Cis-Monoenes And Hydrogenolysis Of Tertiary Allylic Amines
摘要:
Doi:10.1021/jo01312A021

海关参考信息

2905121000-正丙醇
2905130000-正丁醇
2901100000-饱和无环烃
2909199090-其他醚及其衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2010099894-A1
优先权日:2006-10-09
标题 :Method for the Synthesis of Cyclic Acetals by the Reactive Extraction of a Polyol in a Concentrated Solution
发明人：DUBOIS JEAN-LUC; IBORRA CHORNET SARA; VELTY ALEXANDRA I LUCIENNE; CORMA CANOS AVELINO
权利人:DUBOIS JEAN-LUC; IBORRA CHORNET SARA; VELTY ALEXANDRA I LUCIENNE; CORMA CANOS AVELINO
摘要:A method for the synthesis of cyclic acetals comprises reacting at least one carbonyl-function compound selected from aldehydes, ketones, and/or linear acetals, on a polyol in a concentrated aqueous solution exceeding 20 wt % in a reactor containing an acidic catalyst. The carbonyl-function compound is selected so that the cyclic acetal obtained has a water solubility lower than 20000 mg/kg. During the catalytic reaction for the cyclic acetal synthesis, at least one portion of the organic phase containing the cyclic acetal is separated. The acidic catalysis is either homogeneous when using a water-soluble strong acid, or heterogeneous when using a solid acid such as a resin, a zeolite, or any appropriately acidified solid. The extractive reaction method can be used for obtaining high conversions and selectivity.

专利号:US-10308665-B2
优先权日:2015-06-23
标题 :Method for the synthesis of rapamycin derivatives
发明人：ZABUDKIN OLEKSANDR; SCHICKANEDER CHRISTIAN; MATVIIENKO IAROSLAV; SYPCHENKO VOLODYMYR
权利人:SYNBIAS PHARMA AG
摘要:The present invention relates to a method for the production of a rapamycin derivative of formula (I), the method comprising the preparation of a 2-(tri-substituted silyl)oxyethyl triflate by reacting ethylene oxide and a tri-substituted silyl triflate, reaction of the resulting 2-(tri-substituted silyl)oxyethyl triflate with rapamycin in the presence of a molar excess of organic base, and deprotection to obtain the rapamycin derivative of compound (I).

专利号:US-2019010168-A1
优先权日:2015-06-23
标题:Method for the synthesis of rapamycin derivatives

专利号:EP-2076505-A1
优先权日:2006-10-09
标题 :Method for the synthesis of cyclic acetals by the reactive extraction of a polyol in a concentrated solution

专利号:KR-20180015257-A
优先权日:2015-06-23
标题 :Method for the synthesis of rapamycin derivatives

专利号:WO-2008043947-A1
优先权日:2006-10-09
标题 :Method for the synthesis of cyclic acetals by the reactive extraction of a polyol in a concentrated solution