专利号:WO-2018154596-A1 优先权日:2017-02-22 标 题 :Process for synthesis of tiotropium bromide monohydrate 发明人:REDDY G NITHUN; REDDY G SAMHITHA; REDDY G MADAALASA; RAMANI M; REDDY G PRATAP 权利人:GBR LABORATORIES PVT LTD; RACHANA PHARMA TECH 摘要:Provided herein is a process for synthesis of tiotropium bromide wherein the coupling of scopine with 2, 2-dithienyl glycolate is achieved by a two step process under mild conditions.
专利号:US-2006228305-A1 优先权日:2003-02-11 标题 :Pharmaceutical compositions based on anticholinergics and inhibitors of tnf alpha synthesis or action 发明人:MEADE CHRISTOPHER J M; PIEPER MICHAEL P; PAIRET MICHEL 权利人:BOEHRINGER INGELHEIM INT 摘要:The present invention relates to novel pharmaceutical compositions based on anticholinergics and TNF-alpha-antagonists, processes for preparing them and their use in the treatment of respiratory diseases.
专利号:EP-1475379-A1 优先权日:2001-06-28 标题 :Use of scopine ester derivatives for the synthesis of drugs
专利号:KR-20080065313-A 优先权日:2001-06-28 标题 :Scopine ester derivatives used for the synthesis of drugs
专利号:EP-1475379-B1 优先权日:2001-06-28 标题 :Use of scopine ester derivatives for the synthesis of drugs
专利号:CA-2515530-A1 优先权日:2003-02-11 标题 :New pharmaceutical compositions based on anticholinergics and inhibitors of tnf alpha synthesis or action