专利号:US-5679864-A 优先权日:1995-11-03 标题:Process for the synthesis of curcumin-related compounds 发明人:KRACKOV MARK HARRY; BELLIS HAROLD EDWARD 权利人:GENE PRINT INC 摘要:The invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.
专利号:US-9809522-B2 优先权日:2015-09-11 标 题 :Selective liquefaction of lignin and biomass in a mixture of sub- and supercritical fluids in absence or presence of heterogeneous catalysts 发明人:SMIRNOVA ALEVTINA; LYNDE CHRIS; Numan-Al-Mobin Abu Md; RAJAPPAGOWDA RUDRESH BOMMADIHALLI 权利人:SOUTH DAKOTA BOARD OF REGENTS 摘要:Disclosed herein are methods for selective synthesis of specific phenolic products by means biomass or biomass products liquefaction, manipulation of the said selectivity in favor of one specific phenolic compound or a mixture of specific phenolic compounds, and the synthesis of the phenolic compounds from a liquid or biomass organic fraction produced in presence of a homogeneous catalyst in supercritical state or a mixture of said homogeneous and one or several heterogeneous catalysts mixed with water in sub-critical, near-critical, or supercritical condition.
专利号:US-11384367-B2 优先权日:2016-12-22 标题:Synthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms 发明人:GLADDEN JOHN M; SKERKER JEFFREY M; KEASLING JAY D; KIRBY JAMES; YAEGASHI JUNKO 权利人:UNIV CALIFORNIA; NAT TECH & ENG SOLUTIONS SANDIA LLC; BATTELLE MEMORIAL INSTITUTE FOR MANAGEMENT AND OPERATION OF PACIFIC NORTHWEST NAT LABORATORY; NATIONAL TECH AND ENGINEERING SOLUTIONS OF SANDIA LLC 摘要:The present invention provides for a method of converting a depolymerized lignin aromatic compound into a bioproduct, comprising: (a) providing a composition comprising a depolymerized lignin aromatic compound, optionally a depolymerized cellulose, and optionally a depolymerized hemicellulose, and (b) introducing a genetically modified microorganism to the composition, wherein the genetically modified microorganism is capable of converting the depolymerized lignin aromatic compound into a bioproduct; such that the depolymerized lignin aromatic compound is converted into a bioproduct.
专利号:US-5175302-A 优先权日:1987-07-13 标 题 :Nucleophilic fluoroalkylation of aldehydes 发明人:STAHLY G PATRICK 权利人:ETHYL CORP 摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
专利号:US-4837327-A 优先权日:1987-07-13 标 题 :Process for nucleophilic fluoroalkylation of aldehydes 发明人:STAHLY G PATRICK 权利人:ETHYL CORP 摘要:Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
专利号:US-4999429-A 优先权日:1989-01-09 标 题 :Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives 发明人:STAHLY G PATRICK 权利人:ETHYL CORP 摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
1: Gao D, Liu H, Zheng Y, Shi Z, Hu J, Meng F, Zhan X, Liu Q, Zhang Q. An imine- functionalized silicone-based epoxy coating with stable adhesion and controllable degradation for enhanced marine antifouling and anticorrosion properties. Chemistry. 2024 Sep 18:e202403116. doi: 10.1002/chem.202403116. Epub ahead of print. 29(17):4232. doi: 10.3390/molecules29174232. 3: Padhee S, Mohanty D, Sahoo A, Jena S, Chandra Panda P, Ray A, Nayak S. Exploring the mechanism of action of Vanda tessellata extract for the treatment of osteoarthritis through network pharmacology, molecular modelling and experimental assays. Heliyon. 2024 Aug 8;10(16):e35971. doi: 10.1016/j.heliyon.2024.e35971.
合成参考文献
参考文献:10.1007/s11746-009-1486-0 摘要:Khattab R, Eskin M, Aliani M, Thiyam U. Determination of Sinapic Acid Derivatives in Canola Extracts Using High‐Performance Liquid Chromatography. J Americ Oil Chem Soc. 2009 Oct 30;87(2):147–55. doi: 10.1007/s11746-009-1486-0. 参考文献:10.1055/s-2005-871295 摘要:Chou HC, Chen JJ, Duh CY, Huang TF, Chen IS. Cytotoxic and anti-platelet aggregation constituents from the root wood of Melicope semecarpifolia. Planta Med. 2005 Nov;71(11):1078–81. doi: 10.1055/s-2005-871295. 参考文献:10.1055/s-2005-873125 摘要:Luo Y, Zhou M, Qi H, Li B, Zhang G. Novel cadinane and norcadinane sesquiterpenes and a new propanoate from Goldfussia psilostachys. Planta Med. 2005 Nov;71(11):1081–4. doi: 10.1055/s-2005-873125.