CAS: 1139-83-9; 3-Hydroxy-6H-Benzo[c]Chromen-6-One

相似化合物

1143-70-0 35233-17-1 2005-10-9

上下游产品

尿石素a Urolithin A 1143-70-0
3-甲氧基苯并[c]色烯-6-酮 3-Methoxy-6H-Benzo[c]Chromen-6-One 1143-62-0

2-碘苯甲酸乙酯,置于bis-Triphenylphosphine-Palladium(II) Chloride,N-碘代丁二酰亚胺,三溴化硼,Potassium Carbonate,Potassium Hydroxide体系中,用 乙醇,二氯甲烷,水,1,2-二氯乙烷,N,N-二甲基甲酰胺 用作溶剂,化学反应 41.5H,反应生成尿石素b
参考文献:Facile Preparation Of 3,4-Benzocoumarins From 2-Arylbenzoic Acids With Ncs And Nai
标题:Facile Preparation Of 3,4-Benzocoumarins From 2-Arylbenzoic Acids With Ncs And Nai
摘要:Treatment Of 2-Arylbenzoic Acids With N-Chlorosuccinimide (Ncs) And Nai At 70 Degrees C Under Fluorescent Lighting Condition Gave The Corresponding 3,4-Benzocoumarins In Good Yields Under Transition-Metal-Free Condition. It Was Found That The Reactivity Of Ncs With Nai For The Formation Of 3,4-Benzocoumarins From 2-Arylbenzoic Acids Was As High As That With Nis. Thus,The Formation Of Carboxyl Radicals And Their Cyclization Onto An Aromatic Ring From 2-Arylbenzoic Acids With Much Less Expensive Ncs And Nai,Than Nis Could Be Successfully Carried Out To Form 3,4-Benzocoumarins.
Doi:10.3987/com-20-14292

专利信息

专利号:US-9573922-B2
优先权日:2013-12-23
标题:Process-scale synthesis of urolithins
发明人：RINSCH CHRISTOPHER; MUELLER ROLAND; SKRANC WOLFGANG
权利人:AMAZENTIS SA
摘要:Disclosed is a method of preparing a urolithin, or an intermediate or analog thereof, having a dibenzo[b,d]pyran-6-one core. The method is especially advantageous for the large-scale preparation of urolithins or intermediates or analogs thereof. The method may optionally include the preparation of a urolithin, or an intermediate or analog thereof, as a pharmaceutically acceptable salt.

专利号:EP-3087065-A2
优先权日:2013-12-23
标题 :Process-scale synthesis of urolithins

专利号:EP-3663287-B1
优先权日:2013-12-23
标 题 :Process scale synthesis of urolithins

专利号:US-9394269-B2
优先权日:2013-12-23
标题 :Process-scale synthesis of urolithins

专利号:US-2015183758-A1
优先权日:2013-12-23
标 题:Process-Scale Synthesis of Urolithins

专利号:EP-3663287-A1
优先权日:2013-12-23
标 题:Process scale synthesis of urolithins