CAS: 111-87-5; N-Octanol

相似化合物

112-14-1 3386-35-4 106-32-1

上下游产品

CAS号111-11-5 辛酸甲酯 | CAS号1369416-85-2 N,N-diphenyl°Ct... | CAS号2548-87-0 E-2-辛烯醛 | CAS号1118-92-9 N,N-二甲基辛酰胺 | CAS号629-05-0 1-辛炔 | CAS号6998-10-3 °Ctanamide, N-phenyl | CAS号3208-43-3 4-(2-tetrahydro... | CAS号124-07-2 辛酸 | CAS号124-13-0 正辛醛 | CAS号92976-53-9 tert-butyl-dime... | CAS号106144-21-2 4-°Ctoxybenzene... | CAS号104483-29-6 ethenyl °Ctyl c... | CAS号100386-17-2 °Ctyl 2-hydroxy... | CAS号94-50-8 苯甲酸辛酯 | CAS号10348-34-2 2-甲基-4-十一醇 | CAS号104483-19-4 °Ctyl carbonofl... | CAS号109-36-4 十八烷酸辛酯 | CAS号32953-65-4 °Ctyl oleate | CAS号67-56-1 甲醇 | CAS号1071-67-6 °Ctyl N-butylca...

1,2-辛二醇置于三氟甲磺酸,C23H40Iro3P2,氢气体系中,用 1,4-二氧六环 用作溶剂,35.0~195.0 °C,4.14 Mpa 条件下,反应 16.5H,以70%的收率获得辛醇
参考文献:铱在酸性条件下使用氢促进末端环氧化物转化为伯醇†
标题:铱在酸性条件下使用氢促进末端环氧化物转化为伯醇†
摘要:提出了将末端环氧化物转化为伯醇的策略.该反应使用氢作为唯一的化学计量试剂,并在酸性条件下被铱预催化剂促进.对于烷基和芳基取代的末端环氧化物,都观测到在内部醇上形成末端醇的选择性,分离产率分别高达50%和72%.
Doi:10.1039/c9Cy00791A

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人：AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人：NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:US-10711138-B2
优先权日:2016-04-08
标题:Intermediates and procedures for the synthesis of functional materials
发明人：KIRSCH PEER; GUNST SUSANN
权利人:MERCK PATENT GMBH
摘要:The present invention relates to heteroaromatic compounds which have two different reactive groups, their use in the synthesis of asymmetrically substituted compounds, and synthesis processes in which the compounds according to the invention are reacted sequentially with two different compounds, whereby an asymmetrically substituted compound is formed.

专利号:US-10696622-B2
优先权日:2016-08-29
标题 :Synthesis of N-vinyl carboxylic acid amides
发明人：DUMOLEIJN KIM; MOONEN KRISTOF; Henricot Alexis; Han Cai Xing Simon
权利人:TAMINCO BVBA; EASTMAN CHEM CO
摘要:Processes and systems for producing N-vinyl carboxylic acid amides are provided herein. According to some aspects of the present invention, a process for producing an N-vinyl carboxylic acid amide is described that eliminates interim solids handling steps during formation of the intermediate compounds, thereby increasing efficiency and reducing cost. The processes and system described herein may be used for the synthesis of N-vinylformamide and its intermediates, including 1-hydroxyethylformamide and 1-alkoxyethylformamide, or for the synthesis of N-methyl,N-vinylformamide and its intermediates, including N-methyl,1-hydroxyethylformamide and N-methyl,1alkoxyethylformamide.

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人：NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.