专利号:US-7722904-B2 优先权日:2007-11-01 标 题 :Compositions and methods for stimulating synthesis of pro-collagen or collagen and hyaluronic acid 发明人:SCHNEIDER LOUISE M; PUSATERI DONALD J; LA TOM Q 权利人:ACCESS BUSINESS GROUP INT LLC 摘要:A method for improving the appearance, texture and/or moisture of skin comprising administering a composition comprising Chia Seed oil, Opuntia ficus Indica extract, or both to stimulate collagen or hyaluronic acid synthesis, or decrease Interleukin-1b synthesis, in the skin.
专利号:US-6133473-A 优先权日:1998-06-25 标 题 :Synthesis of carbamate compounds 发明人:BERRIER JOHN VINCENT 权利人:ROHM & HAAS 摘要:Disclosed is a method for the preparation of carbamate compounds substantially free of by-products; the carbamate compounds being prepared by reacting an isocyanate with a hydroxylated compound in the presence of certain catalysts that increase the rate of carbamylation while decreasing the rate of by-product formation.
专利号:US-10799441-B2 优先权日:2011-06-06 标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof 发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C 权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC 摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.
专利号:WO-2005016871-A1 优先权日:2003-08-04 标题:Process for the synthesis of iodopropynyl butylcarbamate in an aqueous solution of a suitable surfactant 发明人:SCHNEIDER DAVID J; SCHNEIDER CHARLES A; JONES KURT A; HEINEKE MARTIN S 权利人:H & S CHEMICAL COMPANY INC 摘要:A process for the manufacture of iodopropynyl butylcarbamate (IPBC) is disclosed wherein the subject reaction is carried out in an aqueous solution of a suitable surfactant. The iodination reactant is metallic iodide salt which serves as a donor of I+ ions. The I+ ion is generated on an as needed basis, during the reaction sequence, hence the formation of undesirable isomers of IPBC are minimized. The process of this invention produces a highly purified IPBC having, preferably, a low moisture content (wet-cake). The IPBC produced by such a process is also disclosed herein.
专利号:US-6992208-B2 优先权日:2003-08-04 标题 :Process for the synthesis of iodopropynyl butylcarbamate in an aqueous solution of a suitable surfactant 发明人:SCHNEIDER DAVID J; SCHNEIDER CHARLES A; JONES KURT A; HEINEKE MARTIN S 权利人:H & S CHEMICAL COMPANY INC 摘要:A process for the manufacture of iodopropynyl butylcarbamate (IPBC) is disclosed wherein the subject reaction is carried out in an aqueous solution of a suitable surfactant. The iodination reactant is metallic iodide salt which serves as a donor of I+ ions. The I+ ion is generated on an as needed basis, during the reaction sequence, hence the formation of undesirable isomers of IPBC are minimized. The process of this invention produces a highly purified IPBC having, preferably, a low moisture content (wet-cake). The IPBC produced by such a process is also disclosed herein.
专利号:US-11414365-B2 优先权日:2018-01-30 标题:Natural 1,2-alkanediols, compositions having natural 1,2-alkanediols and processes for making the same 发明人:BURGO ROCCO V; WRIGHT MICHAEL E; MOSSER GARY B; FEVOLA MICHAEL J 权利人:INOLEX INVESTMENT CORP 摘要:A process is incorporated herein for the synthesis of bio-1,2-alkanediols, comprising: providing a bio-alkene having a carbon chain of about 5 to about 20 carbon atoms and a bio-1-alkene regioselectivity of at least about 80%, at least about 92% and/or at least about 95%; and converting the bio-alkene to a bio-1,2-alkanediol having a carbon chain length of about 5 to about 20 carbon atoms. Methods for treating catalysts which may be incorporated in the process for the synthesis of bio-1,2-alkanediols are also included herein. Such bio-1,2-alkanediols are used in compositions and products alone as antimicrobial materials, or with existing bio-compounds and/or antimicrobials, preservatives, alternative preservation systems and/or hurdle technology components. The bio-1,2-alkanediols incorporate a natural and bio-based pathway for antimicrobial effects in various compositions such as cosmetic, pharmaceutical, industrial and household products.
参考文献:10.1007/s00420-017-1203-5 摘要:Schwensen JF, Friis UF, Menné T, Flyvholm M, Johansen JD. Contact allergy to preservatives in patients with occupational contact dermatitis and exposure analysis of preservatives in registered chemical products for occupational use. International Archives of Occupational and Environmental Health. 2017 Feb 06;90(4):319–33. doi: 10.1007/s00420-017-1203-5.