CAS: 74639-14-8; 4-[(2S)-7-Hydroxy-4-Oxo-3,4-Dihydro-2H-Chromen-2-Yl]Phenyl 2-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(Hydroxymethyl)Tetrahydro-2-Furanyl]-β-D-Glucopyranoside
该化合物是食糖(Glycyrrhiza 物种)以生物活性特性而著称的裂变胶,具有显著的抗氧化剂和抗炎效应,成为药物和化妆品研究的焦点,其结构以受硫酰糖约束的硅酰胺为主,与乙酰糖形式相比,提高了溶性性和生物利用率. 碱性在皮肤白化应用中表现出潜力,抑制了抗抑郁酶活动,减少了丙烯酸合成. 此外,由于其自由的激进提取能力,它可能有助于...
- 英文名称4-[(2S)-7-Hydroxy-4-Oxo-3,4-Dihydro-2H-Chromen-2-Yl]Phenyl 2-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(Hydroxymethyl)Tetrahydro-2-Furanyl]-β-D-Glucopyranoside
- 中文名称芹糖甘草苷
- IUPAC名称(S)-2-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-7-hydroxychroman-4-one
- CAS编号74639-14-8
- MFCD编号:MFCD09260034
- FDA UNII编号:8T57TH2CCD
- 分子式:C26H30O13分子量:550.51
- 产品CID: 1736684
- 产品分类天然产物 → 黄酮类化合物
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜1H-Indole-2-Carboxylic Acid (3S,4R,5S)-5-{(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-Hydroxymethyl-2-[4-((S)-7-Hydroxy-4-Oxo-Chroman-2-yl)-Phenoxy]-Tetrahydro-Pyran-3-Yloxy}-3,4-Dihydroxy-Tetrahydro-Furan-3-Ylmethyl Ester置于sodium Methylate体系中,用 甲醇 作为反应溶剂,化学反应 72.0H,以0.7 Mg的收率获得产物甘草苷元-7-O-D-芹糖-4'-O-D-葡萄糖苷
参考文献:来自甘草的酰化黄酮苷和伴随的酚类物质
标题:来自甘草的酰化黄酮苷和伴随的酚类物质
摘要:摘要 从东北甘草(一种商品甘草,被认为是甘草的地下部分)中分离出15种酚类化合物,包括8种新的黄酮苷.阐明了新化合物 (3 R)-Vestitol 7-O-葡萄糖苷和酰化黄酮苷(甘草糖苷 A,B,C1,C2,D1,D2 和 E)的结构.酰化查耳酮芹菜苷的 1 H NMR 和 Cd 光谱数据表明在苷元残基上存在阿魏酰基或对香豆酰基的分子内堆积.
DOI:10.1016/s0031-9422(97)00560-8
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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主要参考文献
1: Guan Y, Li FF, Hong L, Yan XF, Tan GL, He JS, Dong XW, Bao MJ, Xie QM. Protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury. Fundam Clin Pharmacol. 2012 Aug;26(4):473-83. doi: 10.1111/j.1472-8206.2011.00956.x. Epub 2011 Jun 1. doi: 10.3892/mmr.2015.3520. Epub 2015 Mar 20. doi: 10.4268/cjcmm20160208. Chinese. doi: 10.1142/S0192415X13500158. doi: 10.1002/jssc.201500770. Epub 2015 Nov 19. Epub 2004 Dec 22.
10: Guo M, Zhang YF, Wang Y, Zhao XP. [Development of a rapid screening method for discovering neuroprotective components from traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi. 2013 May;38(10):1581-4. Chinese. doi: 10.1016/j.jep.2012.11.005. Epub 2012 Nov 17. Erratum in: J Ethnopharmacol. 2013 Mar 7;146(1):431. doi: 10.1007/s12272-012-1111-x. Epub 2012 Dec 4. Erratum in: Arch Pharm Res. 2013 May;36(5):649. doi: 10.2116/analsci.32.931. doi: 10.1111/j.1745-7254.2008.00850.x. doi: 10.1002/jssc.201600246. Epub 2016 Jul 19. doi: 10.1021/jf5016126. Epub 2014 Jul 29. Epub 2007 Feb 8. eCollection 2012.
合成参考文献
参考文献:10.1248/cpb.41.43
摘要:Kitagawa I, Hori K, Taniyama T, Zhou JL, Yoshikawa M. Saponin and sapogenol. XLVII. On the constituents of the roots of Glycyrrhiza uralensis Fischer from northeastern China. (1). Licorice-saponins A3, B2, and C2. Chem Pharm Bull (Tokyo). 1993 Jan;41(1):43–9. doi: 10.1248/cpb.41.43.
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