CAS: 594-56-9; 2,3,3-Trimethyl-1-Butene

上下游产品

2-methyl-but-2-ene methylene chloride diethyl ether 2-chloro-2,3,3-trimethyl-butane 2-benzoyloxy-2,3,3-trimethyl-butan-1-ol 2,2,3,3-Tetramethyl-1,3-propansulfon 3,3-dimethyl-butan-2-one 2,3,3-trimethyl-2-butanol

📜频哪酮置于potassium Tert-Butylate,甲基三苯基溴化膦体系中,用 四氢呋喃 作为反应溶剂,化学反应 13.0H,反应生成 2,3,3-三乙基-1-丁烯
参考文献:通过 Narasaka-Heck/c(Sp3 或 Sp2)-H 活化级联反应进行钯催化螺环化的实验和计算研究
标题:通过 Narasaka-Heck/c(Sp3 或 Sp2)-H 活化级联反应进行钯催化螺环化的实验和计算研究
摘要:本文报道了通过钯催化串联 Narasaka-Heck/c(Sp 3或 Sp 2)-H 活化反应首次合成高应变螺环丁烷-吡咯啉.这种转变的关键步骤是通过原位反应生成的 σ-烷基-Pd(II) 物质激活 δ-C-H 键,形成五元螺-钯环中间体.通过密度泛函理论(dft)计算探索了整个反应的协同金属化-去质子化(cmd)过程,速率决定步骤和能量势垒.此外,还进行了一系列控制实验以探讨 C(Sp 3)-H 活化步骤的速率决定步骤和可逆性.
DOI:10.1021/jacs.1C04114

专利信息

专利号:WO-2013014486-A1
优先权日:2011-07-28
标题:Improved synthesis of 2-(4-(4-chlorophenyl) cyclohex-1-enyl) -3, 4-dihydronaphthalen-1 (2h)-one; an intermediate for atovaquone
发明人：ROY BHAIRAB NATH; SINGH GIRIJ PAL; LATHI PIYUSH SURESH; AGRAWAL MANOJ KUNJABIHARI; MITRA RANGAN; TRIVEDI AUNRAG
权利人:LUPIN LTD; ROY BHAIRAB NATH; SINGH GIRIJ PAL; LATHI PIYUSH SURESH; AGRAWAL MANOJ KUNJABIHARI; MITRA RANGAN; TRIVEDI AUNRAG
摘要:A process for preparation of 2-(4-(4-chlorophenyl) cyclohex-l-enyl)-3,4-dihydronaphthalen- 1(2H)-one (V), key intermediate for synthesis of Atovaquone [I]. The process for preparation of compound(V) comprising of the steps of; i) Reaction of 2-(4-(4-chlorophenyl)-1-hydroxycyclohexyl)-3,4-dihydronaphthalen- 1(2H)-one (IV) with trifluro acetic anhydride in presence of base in organic solvent to yield compound of formula (XIa) ii) Elimination of trifluoroacetyl functionality of compound (XIa) in organic solvent and in presence of organic base to give compound of formula (V). The invention also provides a Process for preparation of compound(XIa) comprising of the steps of; i) reaction of 2-(4-(4-chlorophenyl)-l-hydroxy cyclohexyl)-3,4-dihydronaphthalen- 1(2H)-one (IV) with trifluro acetic anhydride in presence of organic base in organic solvent. A further process is provided for preparation of compound(V) from compound (XIa) comprising elimination reaction of trifluoroacetyl functionality compound (XIa) in organic solvent and in presence of organic base.

专利号:US-10669160-B2
优先权日:2018-04-30
标题:Heterogeneous wet synthesis process for preparation of high purity tungsten pentahalide
发明人：LIU YUMIN; LI FENG; WAN ZHIWEN; FAFARD CLAUDIA; WIESE STEFAN; HUSSON GUILLAUME; NIKIFOROV GRIGORY; SUI BIN; GIRARD JEAN-MARC
权利人:AIR LIQUIDE; AIR LIQUIDE AMERICAN
摘要:Synthesis of tungsten pentahalide compositions having low impurity profiles are disclosed. The specific impurity profile permits deposition of high purity tungsten-containing films using vapor deposition processes or other semiconductor manufacturing processes without introduction of performance-impacting contaminants.

专利号:US-7855287-B2
优先权日:2007-01-24
标题 :Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity
发明人：DELLA CIANA LEOPOLDO
权利人:CYANAGEN SRL
摘要:A process is described for preparing, efficiently and with a high degree of purity N-alkylsulfonates of phenothiazine. The process consists in (a) the preparation of the phenothiazine anion, and (b) the reaction of said anion with cyclic alkyl sulfonates, such as 1,3-propane sultone and 1,4-butane sultone. This process is simpler, more direct, and more efficient than the procedures currently used for the synthesis of N-alkylsulfonates derivatives of phenothiazine. In addition, the products obtained with this process are far more pure than those obtained through current procedures and therefore ideal for bioanalytical applications that require high sensitivity, such as assays based on the measurement of peroxidase activity using chemiluminescence.

专利号:US-9988349-B2
优先权日:2014-01-03
标 题:Direct stereospecific synthesis of unprotected aziridines from olefins
发明人：ESS DANIEL HALSELL; FALCK JOHN RUSSELL; JAT JAWAHAR LAL; KURTI LASZLO
权利人:ESS DANIEL HALSELL; FALCK JOHN RUSSELL; JAT JAWAHAR LAL; KURTI LASZLO
摘要:A method for the direct stereospecific conversion of structurally diverse mono-, di-, tri- and tetra-substituted olefins to N—H, N-alkyl, N-cycloalkyl, or N-aralkyl aziridines using a hydroxylamine amination agent with transition metal catalyst. The method is operationally simple (i.e., one-pot), scalable and fast at ambient temperature.

专利号:US-6127590-A
优先权日:1999-03-26
标题:Oxidative coupling of olefins and aromatics using a rhodium catalyst and a copper(II) redox agent
发明人：TAUBE DOUGLAS; PERIANA ROY; MATSUMOTO TAKAYA
权利人:NIPPON MITSUBISHI OIL CORP
摘要:This invention relates generally to the field of chemical synthesis, and more specifically, to the field of oxidative coupling of olefinic compounds and aromatic compounds, to produce olefinically substituted aromatic compounds. More particularly, this invention relates to methods for oxidative coupling of olefinic compounds and aromatic compounds which employ a rhodium(III) acetylacetonate catalyst and a copper(II) redox agent in a reaction medium which does not comprise a carboxylic acid component. In one embodiment, this invention pertains to methods for the preparation of styrene by the oxidative coupling of ethylene (an olefinic compound) and benzene (an aromatic compound), in the presence of Rh(acac) 2 Cl(H 2 O), as catalyst, and Cu(II)(CH 3 COO) 2 , as copper(II) redox agent, in which benzene is both a reactant and the reaction medium.

专利号:US-2453144-A
优先权日:1946-05-03
标 题 :Synthesis of organic compounds
发明人：LOVELL WHEELER G; MULLIGAN MAURICE J; LICHTENWALNER HART K
权利人:GEN MOTORS CORP