CAS: 5902-51-2; 3-Tert-Butyl-5-Chloro-6-Methyl-1,2,3,4-Tetrahydropyrimidine-2,4-Dione

该化合物是一种选择性除草剂,主要用于控制各种作物的杂草,特别是甘蔗和其他农业环境中的杂草,属于被称为尿素除草剂的化学品类别,其功能是抑制目标植物中的光合作用.Terbacil的特点是水溶性相对较低,这助长了土壤中的持久性,允许长期的杂草控制.通常根据具体应用和目标杂草,在出现前或出现后施用.化合物具有中度毒性,需要谨慎处理和应用,以尽量减少环境影响和保护非目标物种.Terbacil也受到监管审查,其使用受准则的制约,以确保人类健康和生态系统的安全.

结构式图片

相似化合物

31217-00-2 887581-47-7 6589-37-3

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

3-tert-butyl-6-methyluracil

合成工艺路线路线简述

    3-叔-丁基-6-甲基尿嘧啶置于氯体系中,用 水 作为反应溶剂,化学反应 3.0H,以90%的收率获得产物特草定
    参考文献:一种除草剂特草定的制备方法
    标题:一种除草剂特草定的制备方法
    摘要:本发明公开了一种除草剂特草定的制备方法,其制备步骤包括:以化合物乙酰乙酸乙酯为原料,与氨源反应反应生成3‑氨基巴豆酸乙酯,3‑氨基巴豆酸乙酯再与叔丁基异氰酸酯反应反应生成中间体,中间体氯代得到除草定.该制备方法原料易得,工艺简洁,经济环保,适合工业化生产.

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:BR-102013018473-B1
    优先权日:2012-07-24
    标题 :HERBICIDAL COMPOSITIONS COMPENDIENT 4-AMINO-3-CHLORO-5-FLUORO-6- (4-CHLORO-2-FLUORO-3-ETOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE OF THE SAME AND HERBICIDES INHIBITING THE SYNTHESIS OF VLCFA AND SYNTHESIS OF GRAIN ACID / LIPID, AND METHOD FOR UNDESIRABLE VEGETATION CONTROL
    浙江东风化工有限公司
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    主要参考文献


    1: Thriveni T, Rajesh Kumar J, Sujatha D, Sreedhar NY. Behaviour and quantification studies of terbacil and lenacil in environmental samples using cyclic and adsorptive stripping voltammetry at hanging mercury drop electrode. Environ Monit Assess. 2007 May;128(1-3):359-68. doi: 10.1007/s10661-006-9319-1. Epub 2006 Sep 7. 3(3):268-77. doi: 10.1007/BF02220740. 35(1-2):3-8. 25(2):432-3. doi: 10.1021/jf60210a032. 17(5):1011-3. doi: 10.1021/jf60165a035. 17(5):974-9. doi: 10.1021/jf60165a030. 44(5):331-7. 15(3):1983-1995. doi: 10.1021/acs.jctc.8b01039. Epub 2019 Feb 14. 167(3):162-4. German. doi: 10.1007/BF01122837. 18(1):83-8. doi: 10.1007/BF01686310. 17(5):980-6. doi: 10.1021/jf60165a031. 25(2):373-7. doi: 10.1021/jf60210a031.
    100:233-41. doi: 10.1016/j.ecoenv.2013.08.005. Epub 2013 Sep 6. 62(9):880-5. doi: 10.1002/ps.1252. 18(11):2036-41. doi: 10.1002/elps.1150181126. 397(7):2763-76. doi: 10.1007/s00216-010-3692-x. Epub 2010 Apr 29. 88(6):530-5. doi: 10.1094/PHYTO.1998.88.6.530. 57(3):211-6. Polish. 40(14):4460-6. doi: 10.1021/es0602602. 1218(2):303-15. doi: 10.1016/j.chroma.2010.11.010. Epub 2010 Nov 16.

    合成参考文献


    摘要:National Technical Information Service., OTS0570807
    摘要:Hites, R.A. Handbook of Mass Spectra of Environmental Contaminants. Boca Raton, FL: CRC Press Inc., 1985., p. 356
    摘要:Ashford, R.D. Ashford's Dictionary of Industrial Chemicals. London, England: Wavelength Publications Ltd., 1994., p. 866
    摘要:Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 61
    摘要:Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 67
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