CAS: 50305-43-6; Boc-His(Z)-Oh
该化合物是L-Histidine受保护的衍生物,由Boc(异丙氧碳基)和Z(苯氧碳基)保护组组成.这种化合物在peptide合成中广泛使用,Boc组保护α-氨基功能,Z组保护异丁胺的一环,其主要优势包括高纯度和稳定性,确保固相和溶解阶段的聚苯二酯合成的可靠性能.正方保护战略允许选择性地取消保护,便利受控的peptide链延长.Boc-His(Z)-OH在构建复杂的ptideptide和蛋白质方面特别有用,精确的侧链保护对于避免侧面反应和提高产量至关重要.其一贯的质量使得它成为研究和药物应用的首选.
相似化合物
123333-71-1 14997-58-1 17791-52-5物理性质
MSDS等安全信息
上下游产品
CAS号17791-52-5 B°C-组氨酸合成工艺路线路线简述
海关参考信息
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专利信息
专利号:US-4105602-A
优先权日:1975-02-10
标 题 :Synthesis of peptides with parathyroid hormone activity
发明人：COLESCOTT ROBERT L; TREGEAR GEOFFREY W
权利人:ARMOUR PHARMA
摘要:Resin peptides useful in the preparation of peptides having biological activity, and particularly such resin peptides containing R--CH 2 --O--Phe--Asn at one end of an amino acid chain, R being the resin and Phe and Asn being the residues of the amino acids phenylalanine and asparagine; and processes for the preparation of such resin peptides. Resin peptides are disclosed which contain amino acid chains identical with the amino acid chains of natural peptides having biological activity. Other resin peptides are disclosed which contain amino acid chains in which the amino acid residues differ in kind and sequence from amino acid chains of natural biologically active peptides but from which peptides having biological acitivity may be derived.
专利号:US-4301045-A
优先权日:1977-05-02
标 题:Synthesis of peptides
发明人：KAISER EMIL; COLESCOTT ROBERT L
权利人:ARMOUR PHARMA
摘要:Resin peptides useful in the preparation of peptides having biological activity, and particularly such resin peptides containing Pro-Asp-CH2- or Pro-Asn-CH2- at one end of an amino acid chain, being the resin and Pro, Asp and Asn being the residues of the amino acids proline, aspartic acid and asparagine; and processes for the preparation of such resin peptides.
专利号:US-4242238-A
优先权日:1976-02-13
标 题 :Synthesis of peptides
发明人：BOSSINGER CHARLES D; COLESCOTT ROBERT L; KAISER EMIL
权利人:ARMOUR &
摘要:Resin peptides useful in preparing peptides having biological activity, and particularly such resin peptides containing ALA-GLU-CH 2 - R at one end of an amino acid chain, R being the resin and ALA and GLU being the residues of the amino acids alanine and glutamic acid; and processes for the preparation of such resin peptides. Resin peptides including ACTH 1-28 are disclosed which have adrenocorticotropic activity along with processes for their preparation.
专利号:GB-1524212-A
优先权日:1974-08-12
标 题:Synthesis of salmon calcitonin
