专利号:US-2025197202-A1 优先权日:2023-12-15 标题 :Synthesis of new polymers for the manufacture of solid hydrogen transfer agents 发明人:GÓMEZ EMILIO LEAL; MANCERA LEÓN PABLO TORRES; JUÃ?REZ JORGE ANCHEYTA; MARTÃ?NEZ FERNANDO ALONSO; VÃ?ZQUEZ LAURA OLIVIA ALEMÃ?N 权利人:MEXICANO INST PETROL 摘要:This disclosure refers to a method for the synthesis of polymers with weight average molecular weights greater than 50,000 g/mol, chemically inert, with a minimum decomposition temperature of 425° C., and a main chain composed only of carbon-carbon bonds, which contain structures of the type of naphthalene, phenanthrene, anthracene, pyrene, carbazole or any other where two or more aromatic rings of six carbon atoms of the benzene-type are fused, which may or may not contain aromatic heterocycles. In addition, the polymers obtained from the present disclosure may or may not contain fluorine atoms in their structure. The synthesis described here is carried out by means of polycondensation between a polycyclic aromatic compound and a compound with a carbonyl group in its structure in a strong acid medium.
专利号:US-12247037-B2 优先权日:2018-12-12 标题:1-(2,6-diazaspiro[3.3]heptan-6-yl)-5,6-dihydro-4h-benzo[f][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives and related compounds as vasopressin antagonists for the treatment of neuro-psychological disorders 发明人:BRANDT GARY 权利人:NEUMORA THERAPEUTICS INC 摘要:The present invention relates to 1-(2,6-diazaspiro[3.3]heptan-6-yl)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine derivatives and related compounds of Formula (I): wherein A, B, G, R1, R1b, RiC, R2 and X are as defined herein. The present compounds are vasopressin receptor antagonists (in particular of the Via receptor) for the treatment of neuro-psychological disorders, such as e.g. autism, anxiety, stress-related disorders, depression, schizophrenia or bipolar disorder. The present description discloses the synthesis of exemplary compounds, as well as pharmacological data thereof (e.g. pages 71 to 246; examples 1 to 49; tables 1 to 5). An exemplary compound is e.g. 8-chloro-1-(2-(5-fluoropyridin-2-yl)-2,6-diazaspiro[3.3]heptan-6-yl)-5-methyl-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine (example 1, compound no. 1).
专利号:EP-0042408-A1 优先权日:1979-12-26 标 题 :METHODS OF SYNTHESIS OF HEXAFLUOROISOPROPANOL FROM IMPURE MIXTURES AND SYNTHESIS OF A FLUOROMETHYL ETHER.
专利号:WO-8101843-A1 优先权日:1979-12-26 标 题 :Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
专利号:US-8653223-B2 优先权日:2008-04-16 标题:Transketalized compositions, synthesis, and applications 发明人:SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG 权利人:SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG; SEGETIS INC 摘要:Ketal compounds of the structure I n nand a method of preparation of the compound from polyols and oxocarboxylates, as well as uses thereof.
专利号:US-2012059163-A1 优先权日:2005-04-28 标题 :Non-linear opticaly active molecules, their synthesis, and use 发明人:MCGINNISS VINCENT D; RISSER STEVEN M; DROTLEFF ELIZABETH; JIANG EDWARD; SPAHR KEVIN B 权利人:MCGINNISS VINCENT D; RISSER STEVEN M; DROTLEFF ELIZABETH; JIANG EDWARD; SPAHR KEVIN B; OPTIMER PHOTONICS INC 摘要:In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a Ï€-donor conjugated to a Ï€-acceptor through a Ï€-electron conjugated bridge. In other aspects of the invention, donor structures and acceptor structures are provided. In another aspect of the invention, a chromophore-containing polymer is provided. In one embodiment, the chromophore is physically incorporated into the polymer to provide a composite. In another embodiment, the chromophore is covalently bonded to the polymer, either as a side chain polymer or through crosslinking into the polymer. In other aspects, the present invention also provides a method for making the chromophore, a method for making the chromophore-containing polymer, and methods for using the chromophore and chromophore-containing polymer.
[参考文献]: Laura B Favero, Et Al. How Trifluoroacetone Interacts With Water. J Phys Chem A. 2011 Sep 1;115(34):9493-7. [参考文献]: Telma R Doi, Et Al. 13C Nmr, Infrared, Solvation And Theoretical Investigation Of The Conformational Isomerism In 1-Haloacetones (X = Cl, Br And I). Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jul;61(9):2221-30. [参考文献]: Xiao-Hua Chen, Et Al. Organocatalyzed Highly Enantioselective Direct Aldol Reactions Of Aldehydes With Hydroxyacetone And Fluoroacetone In Aqueous Media: The Use Of Water To Control Regioselectivity. Chemistry. 2007;13(2):689-701.
合成参考文献
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