CAS: 40381-92-8; 2,5,6-Trichloronicotinonitrile

相似化合物

54718-39-7 142266-62-4 126954-66-3

上下游产品

2,3,6-三氯-5-甲基吡啶 2,5,6-Trichloro-3-Methylpyridine 58584-95-5
2,4,5,6-四氯烟腈 2,4,5,6-Tetrachloro-3-Cyanopyridine 17824-82-7
2,5,6-三氯烟酰胺 2,5,6-Trichloronicotinamide 142266-62-4
2,5,6-三氯烟酸 2,5,6-Trichloronicotinic Acid 54718-39-7

3-甲基环戊烷-1,2-二胺置于盐酸,Ammonium Hydroxide,Potassium Permanganate,草酰氯,五氯化磷,硫酸,溶剂黄146,三氯氧磷体系中,用 1,4-二氧六环,二氯甲烷,水 作为反应溶剂,化学反应 48.0H,反应生成 2,5,6-三氯烟腈
参考文献:In Vitro And In Vivo Evaluation Of 6-Aminopyrazolyl-Pyridine-3-Carbonitriles As Jak2 Kinase Inhibitors
标题:In Vitro And In Vivo Evaluation Of 6-Aminopyrazolyl-Pyridine-3-Carbonitriles As Jak2 Kinase Inhibitors
摘要:Synthesis And Biological Evaluation Of A Series Of 6-Aminopyrazolyl-Pyridine-3-Carbonitriles As Jak2 Kinase Inhibitors Was Reported. Biochemical Screening,Followed By Profile Optimization,Resulted In Jak2 Inhibitors Exhibiting Good Kinase Selectivity,Pharmacokinetic Properties,Physical Properties And Pharmacodynamic Effects. (C) 2011 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2011.03.053

专利信息

专利号:CN-113929622-B
优先权日:2021-11-22
标题 :A kind of synthesis method of 2,5,6-trichloronicotine