三聚氯氰 反应生成阿特拉津 参考文献:Gontscharuk W. W.,Wakulenko W. F.,Taran P. N.,Samsoni-Todorow A. O.,Khimija I Tekhnol. Wody,16 (1994) N 3,S 250-255 标题:Gontscharuk W. W.,Wakulenko W. F.,Taran P. N.,Samsoni-Todorow A. O.,Khimija I Tekhnol. Wody,16 (1994) N 3,S 250-255
专利号:US-5455157-A 优先权日:1989-05-22 标 题:Method for the non-radioactive measurement of the nucleic acid synthesis in eukaryotic cells 发明人:HINZPETER MATTHIAS; ELTZ HERBERT VON DER 权利人:BOEHRINGER MANNHEIM GMBH 摘要:For the determination of the rate of nucleic acid synthesis in eukaryotic cells a nucleotide which is non-radioactively labelled or derivatized with a hapten is introduced into the cells with the addition of liposomes and the rate of synthesis of the nucleic acids is determined by means of the incorporation of the nucleotide via its label or derivatization.
专利号:US-2024209407-A1 优先权日:2021-04-26 标 题 :Compositions and methods for phosphoramidite-free enzymatic synthesis of nucleic acids 发明人:STEMPLE DEREK; MANKOWSKA SYLWIA; BELL NEIL 权利人:CAMENA BIOSCIENCE LTD 摘要:Described herein are compositions of matter and methods to synthesize any nucleic acid (NA) sequence using completely natural nucleic acid sources without the need for large-scale phosphoramidite-mediated chemical synthesis.
专利号:US-10987659-B1 优先权日:2020-11-05 标题 :Synthesis of TiO2/Co3O4 core-shell photocatalysts 发明人:KADI MOHAMMAD W; OUF REDA M MOHAMED 权利人:UNIV KING ABDULAZIZ 摘要:A method of synthesizing TiO 2 /Co 3 O 4 core-shell photocatalysts is provided. The method includes preparing SiO 2 hollow nanospheres via sol-gel synthesis in the presence of a triblock copolymer surfactant and a cationic surfactant; adding titanium sec-butoxide to a solution containing the SiO 2 hollow nanospheres to provide a first combined sample; calcinating the first combined sample to provide hollow mesoporous TiO 2 nanospheres; adding cobalt nitrate to a solution comprising the hollow mesoporous TiO 2 nanospheres to provide a second combined sample; and calcinating the second combined sample to provide TiO 2 /Co 3 O 4 core-shell photocatalysts. Methods of producing hydrogen by water-splitting using TiO 2 /Co 3 O 4 core-shell photocatalysts are also provided. Such methods include photodepositing platinum onto the photocatalysts during the reaction.
专利号:US-10865163-B2 优先权日:2017-12-20 标题:Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds 发明人:YOUNG MICHAEL C; KAPOOR MOHIT 权利人:UNIV TOLEDO 摘要:Methods of synthesizing compounds using CO 2 as a directing group for C—H functionalization, and compounds made thereby, are described.
专利号:US-9458471-B2 优先权日:2006-11-03 标题 :Engineered cellular pathways for programmed autoregulation of differentiation 发明人:WEISS RON; LEMISCHKA IHOR; PURNICK PRISCILLA; SCHANIEL CHRISTOPH; MILLER MILES; GUYE PATRICK 权利人:UNIV PRINCETON 摘要:The present invention provides compositions and methods for programming mammalian cells to perform desired functions. In particular, the present invention provides compositions and methods for programming stem cells to differentiate into a desired cell type. A quorum sensing systems that regulates the expression of cell fate regulators is introduced into mammalian host cells, such as stem cells. The quorum sensing systems generally comprises vectors that express the components of a bacterial quorum sensing pathway, including proteins which catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer, and vectors in which genes encoding cell fate regulators are operably linked to a promoter induced by the autoinducer/regulatory partner complex. The system can also comprise vectors in which genes encoding additional cell fate regulators are operably linked to a promoter that is induced by a factor synthesized in response to a first stage of differentiation, so that a second stage of differentiation is triggered.
专利号:US-8192762-B2 优先权日:2005-06-01 标题 :Preparation of soluble and colloidal molecularly imprinted polymers by living polymerization 发明人:KARIM KHALKU; PILETSKY SERGEY ANATOLIYOVICH; PILETSKA OLENA VOLODIMIRIVNA; TURNER ANTHONY PETER FRANCIS; CHIANELLA IVA; GUERRIERO ANTONIO RICARDO LEONARDO 权利人:KARIM KHALKU; PILETSKY SERGEY ANATOLIYOVICH; PILETSKA OLENA VOLODIMIRIVNA; TURNER ANTHONY PETER FRANCIS; CHIANELLA IVA; GUERRIERO ANTONIO RICARDO LEONARDO; UNIV CRANFIELD 摘要:The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.
1: Banasiewicz J, Gumowska A, Hołubek A, Orzechowski S. Adaptations of the Genus Bradyrhizobium to Selected Elements, Heavy Metals and Pesticides Present in the Soil Environment. Curr Issues Mol Biol. 2025 Mar 18;47(3):205. doi: 10.3390/cimb47030205. 43(4):388-393. Chinese. doi: 10.3724/SP.J.1123.2024.06010. 380:124929. doi: 10.1016/j.jenvman.2025.124929. Epub ahead of print. 336:126044. doi: 10.1016/j.saa.2025.126044. Epub ahead of print.
合成参考文献
参考文献:10.1007/s10552-010-9514-9 摘要:Bonner MR, Williams BA, Rusiecki JA, Blair A, Beane Freeman LE, Hoppin JA, Dosemeci M, Lubin J, Sandler DP, Alavanja MCR. Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study. Cancer Causes & Control. 2010 Feb 13;21(6):871–7. doi: 10.1007/s10552-010-9514-9. 参考文献:10.1007/s10661-011-2167-7 摘要:Anjum R, Malik A. Mutagenicity assessment of contaminated soil in the vicinity of industrial area. Environmental Monitoring and Assessment. 2011 Jul 15;184(5):3013–26. doi: 10.1007/s10661-011-2167-7. 参考文献:10.1007/s12672-011-0074-6 摘要:Polanco TA, Crismale-Gann C, Cohick WS. Alcohol Exposure In Utero Leads to Enhanced Prepubertal Mammary Development and Alterations in Mammary IGF and Estradiol Systems. Discover Oncology. 2011 Jun 28;2(4):239–48. doi: 10.1007/s12672-011-0074-6. 参考文献:10.1093/toxsci/kfr176 摘要:Simpkins JW, Swenberg JA, Weiss N, Brusick D, Eldridge JC, Stevens JT, Handa RJ, Hovey RC, Plant TM, Pastoor TP, Breckenridge CB. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence. Toxicol Sci. 2011 Oct;123(2):441–59.