CAS: 14094-11-2; Tert-Butylmethylsulfoxide

相似化合物

1085526-21-1 120982-99-2 14094-12-3

上下游产品

tert-butyl methyl sulphide O-Neopentyl-methansulfinat tert-butylmagnesium chloride Methylsulfinsaeure-n-propylester3-tert-Butylsulfinyl-1-phenyl-propanol-1 methanethiosulfonic acid S-methyl ester S-methyl methanethiosulfinate 3-Methyl-4-(2-methyl-propane-2-sulfinyl)-butyric acid 2,6-di-tert-butyl-4-methyl-phenyl ester

📜叔丁基硫化甲烷置于1-Decyl-4-(Trifluoromethyl)Pyrimidinium Triflate,双氧水体系中,用 Aq. Phosphate Buffer,氯仿 用作溶剂,化学反应 2.0H,以88%的收率获得叔丁基甲砜
参考文献:两亲性吡啶鎓和重氮鎓盐催化的过氧化氢水两相氧化
标题:两亲性吡啶鎓和重氮鎓盐催化的过氧化氢水两相氧化
摘要:在温和的条件下,两亲性吡啶鎓盐和重氮鎓盐被证明是两相(水/氯仿或水/二氯甲烷)硫氧化和n-氧化的有效催化剂.这种史无前例的氧化方法利用过氧化氢与简单的吡啶鎓或重氮鎓原子的共价键合来增加氢过氧化物种类的亲脂性,并随后将其活化以在非极性介质中氧化.发现催化效率取决于杂芳烃核的类型和催化剂的亲脂性.制备并研究了五种系列的杂芳烃催化剂:1-烷基-3,5-二氰基吡啶鎓,1-烷基-3,5-二硝基吡啶鎓,1-烷基-3-氰基吡啶鎓,1-烷基-4-氰基吡啶鎓和1-烷基-4-(三氟甲基)嘧啶鎓三氟甲磺酸酯(烷基=丁基,己基,辛基,癸基,十二烷基和十六烷基).其中,发现1-辛基-3,5-二硝基吡啶鎓和1-癸基-4-(三氟甲基)嘧啶鎓三氟甲磺酸酯是非常好的催化剂,表现出最佳的稳定性和最高的催化活性,相对于350倍的加速作用非催化反应.与使用过氧化氢的其他有机催化两相氧化相反,本方法的特点是化学选择性高,催化剂负载量低(5
Doi:10.1002/adsc.201500687

专利信息

专利号:US-5449795-A
优先权日:1994-02-14
标 题 :Process for synthesis of steroidal allylic tert. alcohols
发明人：HOGENKAMP DERK J
权利人:COCENSYS INC
摘要:A method for the preparation of a steroidal allylic tertiary alcohol is disclosed which involves the deprotonation of a sulfoxide with a strong base which is capable of deprotonating the methine proton which is α to the sulfoxide, in an inert solvent to give the anion; reaction of the anion with a steroidal spiro-2'-oxirane to give a steroidal γ-hydroxysulfoxide; and thermolysis in the presence of a base other than calcium carbonate to give the steroidal allylic tertiary alcohol.

专利号:US-7642369-B2
优先权日:2006-09-12
标 题 :Epoxyketone-based immunoproteasome inhibitors
发明人：KIM KYUNG BO; HO YIK KHUAN
权利人:UNIV KENTUCKY RES FOUND
摘要:An efficient new route for the preparation of dihydroeponemycin, an active eponemycin derivative, is provided, which includes the synthesis of the intermediate compound, a hydroxymethyl-substituted enone. In addition, a method is provided for synthesizing inhibitors, which includes PI′-modified analogues. These analogues selectively bind to a major immunoproteasome catalytic subunit LMP2 and inactivate its proteolytic activity in a method of treating diseases, including myeloma and other cancers, Huntington's disease and Alzheimer's disease.

专利号:US-2021122755-A1
优先权日:2016-07-01
标 题:Synthesis of n-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines

专利号:US-2019135820-A1
优先权日:2016-07-01
标题:Synthesis of n-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines

专利号:WO-0216570-A1
优先权日:2000-08-21
标题:Dms:acceptor oxidoreductase
发明人：MCDEVITT CHRISTOPHER ADRIAN; MCEWAN ALASTAIR GRAHAM
权利人:UNIV QUEENSLAND; MCDEVITT CHRISTOPHER ADRIAN; MCEWAN ALASTAIR GRAHAM
摘要:A recombinant bacterial DMS:acceptor oxidoreductase, subunit amino acid sequences andencoding nucleic acids are provided. The DMS:acceptor oxidoreductase is enantioselective with respect to prochiral organic sulfoxide substrates. The DMS:acceptor oxidoreductase is useful in methods of oxidizing prochiral organic sulfides to form corresponding sulfoxides, and more particularly, to form sulfoxide (S) enantiomers which may be used in the synthesis of chiral drugs.

专利号:US-10865210-B2
优先权日:2016-07-01
标题 :Synthesis of n-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines