CAS: 13980-14-8; 2-Hydroxydocosanoic Acid

上下游产品

α-bromobehenic acid ethanol 2-acetoxy-d°Cosanoic acid ethyl ester ethyl d°Cosanoate 2-hydroxy-d°Cosanoic acid benzyl ester 2-Trifluoromethanesulfonyloxy-d°Cosanoic acid benzyl ester

📜山嵛酸乙酯置于potassium Carbonate,Lithium Diisopropyl Amide体系中,用 四氢呋喃,甲醇,二氯甲烷,甲苯 用作溶剂,化学反应生成2-羟基二十二酸
参考文献:Role Of The Hydrophobic Moiety Of Tumor Promoters. Synthesis And Activity Of 2-Alkylated Benzolactams
标题:Role Of The Hydrophobic Moiety Of Tumor Promoters. Synthesis And Activity Of 2-Alkylated Benzolactams
摘要:The Size And Position Of A Hydrophobic Moiety On A Benzolactam Skeleton,Which Reproduces The Active Conformation And Biological Activity Of Teleocidins,Play An Important Role In The Appearance Of The Activity. Compounds With Alkyl Groups Of Various Sizes And Shapes At The 2-Position Of Benzolactam Were Synthesized. Structure-Activity Results Indicate That A Hydrophobic Substituent At The C-2 Position Plays A Critical Role In The Appearance Of Biological Activities,As In The Case Of Substitution At C-9. (C) 1999 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0960-894X(99)00580-6

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:EP-0640068-A1
优先权日:1992-05-07
标 题 :Synthesis of cosmetic ingredient

专利号:CA-2135181-A1
优先权日:1992-05-07
标题:Synthesis of cosmetic ingredient

专利号:CN-119143573-A
优先权日:2023-06-15
标 题 :A synthesis method of 1,2-diol and its application in cosmetics