CAS: 13734-34-4; Boc-Phe-Oh

上下游产品

CAS号63-91-2 L-苯丙氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号66605-57-0 N-B°C-L-苯丙氨醇 | CAS号51987-73-6 N-B°C-L-苯丙氨酸甲酯 | CAS号116400-16-9 (+)-tert-butyl ... | CAS号142955-51-9 b°C-phe-n-carbo... | CAS号98015-52-2 tert-butyl 1,2,... | CAS号185509-03-9 tert-butyl ((R)... | CAS号17790-88-4 N-tert-Butyloxy... | CAS号58632-95-4 2-(叔-丁氧基碳酰胺)-2-苯乙腈 | CAS号3303-55-7 L-苯丙氨酰-L-亮氨酸 | CAS号37553-65-4 B°C-N-甲基-L-苯丙氨酸 | CAS号37553-64-3 N-B°C-N-methyl-... | CAS号37462-62-7 叔丁氧羰酰基Β环己基丙氨酸二环己胺盐 | CAS号33507-63-0 P物质 | CAS号57462-42-7 [Nle11]-物质P. | CAS号37736-82-6 B°C-L-环己基丙氨酸 | CAS号3182-95-4 L-苯丙氨醇 | CAS号34290-59-0 b°C-phe-ser-ome | CAS号33014-68-5 叔丁氧羰基-L-苯丙酰-L-亮氨酸

N-Boc-L-苯丙氨醇置于potassium Hydrogensulfate,2,2,6,6-四甲基哌啶氧化物,Copper(II) Nitrate Trihydrate,氧气体系中,用 1,2-二氯乙烷 用作溶剂,以93%的收率获得boc-L-苯丙氨酸
参考文献:铜催化伯醇有氧氧化成羧酸
标题:铜催化伯醇有氧氧化成羧酸
摘要:在这里,开发了第一个以 Tempo 和 Khso 4作为助催化剂的铜催化伯醇有氧氧化成羧酸的反应.该反应在温和条件下表现出优异的底物范围和官能团相容性.即使是非常敏感的手性醇,手性氨基醇和含醇的类固醇骨架也可以被氧化以提供相应的羧酸或内酯而无需外消旋化.
Doi:10.1039/d3Cc00963G

专利信息

专利号:WO-2024151344-A9
优先权日:2022-11-18
标题:A device that enables the combinatorial synthesis of small molecule libraries
发明人：COPELAND Gregory; LIU JANE
权利人:BRT BIOTECHNOLOGIES INC
摘要:A device for the synthesis of small molecules on a substrate is provided. The device includes a synthesis plate with vias, and a microfluidic patterning plate with a series ot open-faced channels that can be aligned with the vias on the synthesis plate. The device may be used to synthesize combinatorial libraries of small molecules.

专利号:US-5817751-A
优先权日:1994-06-23
标 题 :Method for synthesis of diketopiperazine and diketomorpholine derivatives
发明人：SZARDENINGS ANNA KATRIN; CAMPBELL DAVID
权利人:AFFYMAX TECH NV
摘要:The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such methods to create libraries of diverse diketopiperazine derivatives. The present invention has application in the areas of chemical synthesis, the screening for new diketopiperazine derivatives having beneficial medical properties and the use of such screening to provide compositions and methods including diketopiperazine derivatives for treating disease.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-2018265547-A1
优先权日:2014-07-18
标 题 :Z-selective olefin metathesis of peptides
发明人：MANGOLD SHANE L; GRUBBS ROBERT H
权利人:CALIFORNIA INST OF TECHN
摘要:The invention relates generally to the synthesis of modified amino acids and modified peptides in the presence of cyclometalated catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.

专利号:US-9862745-B2
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds
发明人：AMMOSCATO VINCE; BISHOP JOHN E; CHIU FANG-TING; GEISER ACHIM; GOMEZ JEAN-MARC; HETT ROBERT; KOELLNER CHRISTOPH; KULKARNI VITHALANAND R; LO YOUNG; MUNK STEPHEN; PICKERSGILL I FRASER
权利人:MILLENNIUM PHARM INC; MILLENNIUM PHARM INC
摘要:The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.

专利号:US-4242256-A
优先权日:1977-03-15
标 题 :Synthesis of peptide analogues
发明人：SHARPE ROBERT; SZELKE MICHAEL
权利人:SHARPE ROBERT; SZELKE MICHAEL
摘要:Compounds being analogues of a dipeptide in which the nitrogen atom of the linking amide group of the dipeptide is replaced by trivalent group ##STR1## and in which, optionally, the carbonyl function of this linking group is replaced by the divalent group --CH 2 -- are of value in the synthesis of isosterically modified peptides.