CAS: 127892-62-0; 4-Chloro-3-Ethyl-1-Methyl-1H-Pyrazole-5-Carboxylic Acid

相似化合物

514800-80-7 124800-34-6 1126223-57-1

上下游产品

4-氯-3-乙基-1-甲基吡唑-5-甲酸乙酯 Ethyl 4-Chloro-3-Ethyl-1-Methyl-1H-Pyrazole-5-Carboxylate 124800-34-6
3-乙基-1-甲基-1H-吡唑-5-甲酸乙酯 Ethyl 3-Ethyl-1-Methyl-1H-Pyrazole-5-Carboxylate 128537-26-8

2,4-二氧代己酸乙酯置于氯化亚砜,Sodium Hydroxide体系中,用 乙醇,水,1,2-二氯乙烷 用作溶剂,化学反应 8.0H,反应生成4-氯-3-乙基-1-甲基吡唑-5-甲酸
参考文献:1H-吡唑-5-羧酰胺衍生物作为潜在杀真菌和杀虫剂的设计,合成和生物学评价
标题:1H-吡唑-5-羧酰胺衍生物作为潜在杀真菌和杀虫剂的设计,合成和生物学评价
摘要:摘要通过简便的方法设计和合成了一系列含有苯基噻唑部分的新型1H-吡唑-5-羧酰胺化合物,并通过1 H NMR,质谱和元素分析对其结构进行了表征.生物测定结果表明,大多数标题化合物显示强大的杀菌活性对小麦白粉病和抗杀虫活性蚜蚜.特别是,化合物9B具有ec 50为3.04毫克值/ L抵抗禾白粉菌,其中的杀真菌活性比商业杀真菌剂和的thifluzamide的azoxystrobinare更好; 化合物9L的lc 50蚜虫的3.81 Mg / L的值与商业杀虫剂tolfenpyrad相当.建议将含有苯基噻唑部分的1H-吡唑-5-羧酰胺化合物视为进一步设计农药的前体结构. 图形概要通过简便的方法设计和合成了一系列含有苯基噻唑部分的新型1H-吡唑-5-羧酰胺化合物,并通过1 H NMR,质谱和元素分析对其结构进行了表征.生物测定结果表明,大多数标题化合物显示强大的杀菌活性对小麦白粉病和抗杀虫活性蚜蚜.特别是,化合物9B具有ec
Doi:10.1007/s11696-017-0198-4

专利信息

专利号:CN-101307022-B
优先权日:2008-06-30
标题:Green Synthesis of 1-Methyl-3-Ethyl-4-Chloro-5-Pyrazolecarbonyl Chloride

专利号:WO-2025055006-A1
优先权日:2023-09-13
标 题 :Matrine derivative, preparation method therefor, and use thereof
发明人：ZHANG JIE; CHEN TINGZHUO; RONG BO; QIAN SHAN; TANG QINGQING; DU BO; WU YUXIANG; REN DAN; HE QIMING
权利人:CHENGDU NEWSUN CROP SCIENCE CO LTD
摘要:The present application relates to the field of organic synthesis. Disclosed are a matrine derivative, a preparation method therefor, and a use thereof. By taking sophora acid methyl ester as a raw material, a nucleophilic substitution or nucleophilic addition reaction is carried out under an alkaline condition, to obtain a series of new matrine derivatives in one step. The matrine has certain insecticidal activity, but the insecticidal effect is not ideal; however, the activity of the matrine is multiplied by modifying the structure of the matrine and is obviously superior to that of the matrine before structural modification; in addition, some compounds also have an inhibitory effect on the activity of SIRT enzymes.

专利号:CN-102267986-B
优先权日:2011-09-01
标 题 :A kind of pyrazole bisamide compound and its synthesis method and application