CAS: 127061-56-7; Epc-K(1)
- 英文名称Epc-K(1)
- 中文名称钾[(5R)-5-[(1S)-1,2-二羟基乙基]-2-羟基-4-氧代呋喃-3-基][(2R)-2,5,7,8-四甲基-2-[(4R,8R)-4,8,12-三甲基十三烷基]色满-6-基]磷酸氢酯
- IUPAC名称potassium (R)-5-((S)-1,2-dihydroxyethyl)-4-hydroxy-2-oxo-2,5-dihydrofuran-3-yl ((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl) phosphate
- CAS编号127061-56-7
- MFCD编号:MFCD00903186
- FDA UNII编号:61R4GJ48ER
- 分子式:C35H56KO10P分子量:706.89
- 产品CID: 432180
- 产品分类Inhibitors/Agonists → Cell Cycle → Casein Kinase
物理性质
MSDS等安全信息
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海关参考信息
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2902600000-乙苯
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专利信息
专利号:US-2009232915-A1
优先权日:2008-03-14
标 题 :Mixtures with a collagen synthesis boosting action
发明人：SCHMAUS GERHARD; FRANKE HELGE; LANGE SABINE
权利人:SYMRISE GMBH & CO KG
摘要:The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.
专利号:US-9314021-B2
优先权日:2004-11-03
标题 :Formulations containing insect repellent compounds
发明人：SCIALDONE MARK A
权利人:DU PONT
摘要:Dihydronepetalactone, a minor natural constituent of the essential oil of catmints ( Nepeta spp.) such as Nepeta cataria , has been identified as an effective insect repellent compound. Synthesis of dihydronepetalactone may be achieved by hydrogenation of nepetalactone, the major constituent of catmint essential oils. This compound, and compositions thereof, which also has fragrance properties, may be used commercially for its insect repellent properties.
专利号:WO-2006053688-A1
优先权日:2004-11-17
标 题:Cosmetic and dermatological preparations for the treatment of mature skin
发明人：DOERING THOMAS
权利人:HENKEL KGAA; DOERING THOMAS
摘要:The invention relates to topical cosmetic or dermatological compositions for the treatment of mature or intrinsically or extrinsically aged skin, in particular, for anti-wrinkle treatment, containing a combination of at least two selected peptides in a suitable cosmetic or dermatological vehicle, which have an effect at differing points of the process of collagen and/or fibronectin synthesis.
专利号:WO-2006042625-A2
优先权日:2004-10-15
标 题 :Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators
专利号:EP-1799311-A2
优先权日:2004-10-15
标 题:Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators
专利号:EP-2271614-A2
优先权日:2008-03-28
标 题:Method for the continuous synthesis of an n-acylated compound, and equipment for implementing said method
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Zingg JM, Azzi A, Meydani M. α-Tocopheryl Phosphate Induces VEGF Expression via CD36/PI3Kγ in THP-1 Monocytes. J Cell Biochem. 2017 Jul;118(7):1855-1867. doi: 10.1002/jcb.25871. Epub 2017 Mar 24.
745:98-107. doi: 10.1016/j.ejphar.2014.09.050. Epub 2014 Oct 15. 9(11):e111833. doi: 10.1371/journal.pone.0111833.
4: Oishi K, Hagiwara S, Koga S, Kawabe S, Uno T, Iwasaka H, Noguchi T. The vitamin E derivative, EPC-K1, suppresses inflammation during hepatic ischemia- reperfusion injury and exerts hepatoprotective effects in rats. J Surg Res. 2012 Jul;176(1):164-70. doi: 10.1016/j.jss.2011.03.080. Epub 2011 Apr 28. 33(6):485-90. doi: 10.1159/000327820. Epub 2011 May 3. 168(2):173-4. doi: 10.1016/j.jss.2010.06.027. Epub 2010 Sep 8. 34(4):734-8. doi: 10.1007/s11064-008-9811-9. Epub 2008 Aug 8. 293(6):R2218-24. doi: 10.1152/ajpregu.00295.2007. Epub 2007 Sep 26. 28(5-6):538-90. doi: 10.1016/j.mam.2007.07.001. Epub 2007 Aug 3. 26(6):610-6. doi: 10.1016/j.healun.2007.03.013. 9(4):310-314. doi: 10.1007/s10157-005-0374-7. 11(1):4-6. 58(3):111-8. doi: 10.18926/AMO/32111. 10(19):2401-10. doi: 10.2174/1381612043384015. 120(2):312-9. doi: 10.1016/j.jss.2003.12.004. 27(6):831-4. doi: 10.1248/bpb.27.831. 67(12):1046-52. doi: 10.1253/circj.67.1046. 145(6):489-93; discussion 493. doi: 10.1007/s00701-003-0036-z. 21 Suppl
合成参考文献
摘要:International Journal of Toxicology 21(Suppl. 3):51-116, 2002
摘要:Final Report 3/2014 Available from CIR
参考文献:10.1016/s0300-483x(99)00030-x
摘要:Wei T, Chen C, Hou J, Zhao B, Xin W, Mori A. The antioxidant EPC-K1 attenuates NO-induced mitochondrial dysfunction, lipid peroxidation and apoptosis in cerebellar granule cells. Toxicology. 1999 Jun 15;134(2-3):117–26. doi: 10.1016/s0300-483x(99)00030-x.
参考文献:10.1023/b:agen.0000029390.09354.f8
摘要:Ashino H, Shimamura M, Nakajima H, Dombou M, Kawanaka S, Oikawa T, Iwaguchi T, Kawashima S. Novel function of ascorbic acid as an angiostatic factor. Angiogenesis. 2003;6(4):259–69. doi: 10.1023/b:agen.0000029390.09354.f8.
参考文献:10.1002/hep.510300601
摘要:Kumamoto Y, Suematsu M, Shimazu M, Kato Y, Sano T, Makino N, Hirano KI, Naito M, Wakabayashi G, Ishimura Y, Kitajima M. Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver. Hepatology. 1999 Dec;30(6):1454–63. doi: 10.1002/hep.510300601.
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