CAS: 11017-56-4; 2H-Indeno[1,2-B]Furan-2-One,3-[[[(2R)-2,5-Dihydro-4-Methyl-5-Oxo-2-Furanyl]Oxy]Methylene]-3,3A,4,5,6,7,8,8B-Octahydro-5-Hydroxy-8,8-Dimethyl-,(3E,3Ar,5S,8Bs)-

专利信息

专利号:US-2023248849-A1
优先权日:2020-07-27
标 题:Contrast agents for detection of enzyme activities based on melanin synthesis
发明人：PAGEL MARK D
权利人:UNIV TEXAS
摘要:We disclose a composition, comprising a compound, comprising a melanin precursor that spontaneously synthesizes a melanin when in free form in vivo, and a peptide directly covalently bonded to or indirectly linked to the melanin precursor, wherein the direct covalent bond or indirect link of the peptide to the melanin precursor blocks spontaneous synthesis of the melanin in vivo in the absence of protease activity. We also disclose methods of tumor imaging, tumor detection, diagnosis, and treatment, including methods comprising administering, to a patient suffering from a tumor, the composition; and either surgically resecting the tumor or thermally ablating the tumor, wherein the surgical resection is guided at least in part by contrast imparted by, or the thermally ablating targets cells containing, the melanin, wherein the melanin is spontaneously synthesized in the tumor after administering the composition.

专利号:US-4259512-A
优先权日:1976-10-15
标 题 :Method of synthesis for a chemical precursor to strigol
发明人：DOLBY LLOYD J
权利人:STATE BOARD OF HIGHER EDUCATIO
摘要:Preparation of 5,5-Dimethyl-8-carboalkoxybicyclo [4.3.0]non-1-(6)-ene-2,7-dione by condensing dimethylpyruvic acid and 5-ono-6-heptenoic acid to produce a dibasic acid. Esterification of the acid produces a diester which is cyclized to produce the compound.

专利号:US-4002459-A
优先权日:1974-04-18
标题 :Germination factors
发明人：JOHNSON ALAN W; ROSEBERY GERALD
权利人:INT DEV RESEARCH CENTER
摘要:Active compounds, some of which are new, are described for the control of various parasitic weeds of the genus Striga and Orobanche. These compounds all include cyclic lactone structures and are related to the naturally occurring substance strigol. Methods of synthesis of the compounds are given, as well as compositions and methods for controlling the parasitic weeds.

专利号:CN-114369087-B
优先权日:2022-02-07
标 题:Synthesis and Application of Lactone Analogs with Indolin-2-one Skeleton

专利号:CN-110615784-A
优先权日:2019-10-25
标题:Synthesis and Application of Lactone Analogs with Flavonoid Skeleton

专利号:CN-110615784-B
优先权日:2019-10-25
标 题 :Synthesis and application of lactone analogue with flavone skeleton