CAS: 1079043-55-2; Deudextromethorphan

上下游产品

右美沙芬 Dextromethorphan 125-71-3

📜右美沙芬置于1-氯乙基氯甲酸酯,氢溴酸,Potassium Carbonate,溶剂黄146,Potassium Iodide,Sodium T-Butanolate体系中,用 水,N,N-二甲基甲酰胺,甲苯 用作溶剂,化学反应 20.17H,反应生成六氘代右美沙芬
参考文献: Industrial Process Of Mono-Alkylating A Piperidine Nitrogen In Piperidine Derivatives With Deuterated-Alkyl[fr] Procédé Industriel De Monoalkylation D'Un Azote De Pipéridine Dans Des Dérivés De La Pipéridine Avec Un Alkyle Deutéré
标题: Industrial Process Of Mono-Alkylating A Piperidine Nitrogen In Piperidine Derivatives With Deuterated-Alkyl[fr] Procédé Industriel De Monoalkylation D'Un Azote De Pipéridine Dans Des Dérivés De La Pipéridine Avec Un Alkyle Deutéré
摘要:本发明涉及一种用氘代低烷基对哌啶衍生物中的哌啶氮进行单烷基化的方法,包括用芳基保护基保护哌啶氮,使用氘代低烷基化试剂在中性或碱性条件下对哌啶氮进行低烷基化,然后去除芳基保护基.

专利信息

专利号:US-2023002411-A1
优先权日:2019-12-20
标 题:Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents
发明人：ARSENJANS PAVELS
权利人:LATVIAN INST ORGANIC SYNTHESIS
摘要:The present invention relates to a novel cancer curing deuterated selenopheno [h] chromene derivatives, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment of cancer by administration of such substances.

专利号:US-12291505-B2
优先权日:2016-07-04
标题 :Methods for the synthesis of deuterated dextromethorphan
发明人：JOHNSON MATT; ZHAO CUNXIANG; MENG WEIHUA; LU ZHIJUN; LI YAN
权利人:AVANIR PHARMACEUTICALS INC
摘要:The application describes methods for making a deuterated dextromethorphan of Formula (I), deuterated dextromethorphan produced by these methods, and pharmaceutically acceptable salts thereof.

专利号:US-2024124402-A1
优先权日:2016-07-04
标 题:Methods for the synthesis of deuterated dextromethorphan

专利号:US-2024067608-A1
优先权日:2016-07-04
标 题:Methods for the synthesis of deuterated dextromethorphan

专利号:EP-3478664-B1
优先权日:2016-07-04
标题 :Methods for the synthesis of deuterated dextromethorphan

专利号:US-2019241525-A1
优先权日:2016-07-04
标题:Methods for the synthesis of deuterated dextromethorphan