📜三氟化氯,Cobalt(II) Chloride 以 Neat (No Solvent) 用作溶剂,化学反应生成三氟化钴 参考文献:The Use Of Chlorine Trifluoride As A Fluorinating Agent 标题:The Use Of Chlorine Trifluoride As A Fluorinating Agent 摘要: Doi:10.1021/ja01126A526
专利信息
专利号:US-9896336-B2 优先权日:2008-06-11 标 题:Bromine-facilitated synthesis of fluoro-sulfur compounds 发明人:WINTER ROLF 权利人:AVANTBIO CORP 摘要:Described herein are methods for the bromine-facilitated synthesis of fluoro-sulfur compounds, that include SF 4 , SF 5 Cl, SF 5 Br and SF 6 . The methods described herein generally require lower temperature and pressure, produce higher yields, require less time, do not use corrosive or costly reactants and solvents that are commonly used in the synthesis of the fluoro-sulfur compounds, and do not produce deleterious waste products when compared to previously-used methods.
专利号:US-6225511-B1 优先权日:1990-10-26 标题 :Synthesis of fluorinated ethers 发明人:CHAMBERS OWEN ROSS; SIMPSON RODERIC NIGEL FRASER 权利人:RHONE POULENC CHEMICALS 摘要:Fluorinated ethers of the formula:wherein R is hydrogen, fluorine, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, R' is hydrogen, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, and R'' is fluorine, alkyl of 1 to 6 carbon atoms or fluoroalkyl of 1 to 6 carbon atoms are prepared by fluorinating a corresponding ether of formula:with a solid transition metal fluoride fluorinating agent such as cobaltic fluoride.
专利号:US-2011091370-A1 优先权日:2009-10-15 标 题 :Mechanochemical Synthesis of Carbon Fluorides and an Electrochemical Cell using the Synthesized Carbon Fluorides 发明人:BEHL WISHVENDER K; READ JEFFREY A 权利人:US GOV SEC ARMY 摘要:Carbon fluoride is synthesized by reactively or high intensity/energy milling at ambient room temperature carbon-containing material (such as graphite, carbon black, coke, or other carbon-based material) with an inorganic fluoride agent (such as cobalt trifluoride) other than fluorine gas. The following chemical reaction occurs: xC+CoF 3 →C x F+CoF 2 , wherein x equals 1 to 4. The C x F is separated from the CoF 2 and the CoF 3 by digesting the C x F, CoF 2 and the CoF 3 in hot water of at least approximately 90° C. causing the CoF 2 to dissolve; and then filtering the CoF 2 . The CoF 3 is unreacted and undergoes hydrolysis in the hot water to form Co(OH) 3 or Co 2 O 3 .3H 2 O, which is removed by washing with sulfuric acid. Alternatively, the C x F is separated from the CoF 2 and the CoF 3 by digesting the C x F, CoF 2 and the CoF 3 in heated sulfuric acid followed by filtration and washing with sulfuric acid and then with hot water. The synthesized carbon fluoride is used to form a cathode in electrochemical cells, such as lithium batteries.
专利号:US-12398116-B2 优先权日:2020-09-10 标题:Total synthesis of alectinib 发明人:ZHOU LIHUA 权利人:SUZHOU FUDE ZHAOFENG BIOCHEMICAL TECH CO LTD 摘要:The present invention relates to a process for preparing alectinib or a pharmaceutically acceptable salt thereof. The present invention also relates to intermediate compounds which are useful in such process and to the preparation of such intermediate compounds.
专利号:US-5026929-A 优先权日:1990-02-08 标题:Synthesis of highly fluorinated aromatic compounds 发明人:MARSELLA JOHN A; PEZ GUIDO P; COUGHLIN ANNE M 权利人:AIR PROD & CHEM 摘要:A process is disclosed for making a highly fluorinated aromatic compound by contacting a perfluorocycloalkane, such as perfluorodecahydronaphthalene, with a complex of a metal from Groups IA and IIA of the Periodic Table and an organic electron acceptor. The reaction is carried out in an organic solvent and under reducing conditions which are relatively moderate. Best results are obtained using a perfluorocycloalkane having 2-4 condensed rings and a complex of either sodium or lithium and benzophenone thereby making a perfluorinated condensed ring aromatic compound such as perfluoronaphthalene or perfluorophenanthrene.
专利号:US-2019359485-A1 优先权日:2008-06-11 标 题:Bromine-Facilitated Synthesis of Fluoro-Sulfur Compounds
摘要:Schiltz, P.; Gao, M.; Gosmini, C., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 309. 摘要:Kordnezhadian, R.; De Borggraeve, W. M.; Ismalaj, E., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 2. 摘要:Ruskin, J.; Lectka, T., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2. 参考文献:10.1007/s00232-003-0614-2 摘要:Castelli L, Tanzi F, Taglietti V, Magistretti J. Cu 2+ , Co 2+ , and Mn 2+ Modify the Gating Kinetics of High-Voltage-Activated Ca 2+ Channels in Rat Palaeocortical Neurons. Journal of Membrane Biology. 2003 Oct 01;195(3):121–36. doi: 10.1007/s00232-003-0614-2.