CAS: 10009-70-8; (R)-2-Bromopropanoic Acid

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上下游产品

L-alanin D-Alanine (2R)-methyl 2-bromopropionate 2-Bromopropionic acid (2S,2'S)-2,2'-Iminobis(propionsaeure) N-(2-bromo-propionyl)-alanineN-(2-bromo-propionyl)-alanine (S),(S)-°Ctopine L-Lactic acid

合成工艺路线路线简述

  • 合成目标产物 (R)-(+)-2-Bromopropionic Acid 主要起始原料 (S)-2-((Methylsulfonyl)Oxy)Propanoic Acid
  • (文献来源)合成步骤主要原料 (S)-2-((Methylsulfonyl)Oxy)Propanoic Acid
📜L-丙氨酸置于nitrosyl Bromide体系中,化学反应生成(R)-(+)-2-溴丙酸
参考文献:Fischer,E.,Chemische Berichte,1907,Vol. 40,P. 491
标题:Fischer,E.,Chemische Berichte,1907,Vol. 40,P. 491

海关参考信息

专利信息


专利号:US-8338621-B2
优先权日:2005-12-21
标题:Process for the preparation of 2-oxo-1-pyrrolidine derivatives
发明人:SURTEES JOHN; BOUVY DIDIER; THOMAS ANTOINE; COMBRET YVES; FRANK MICHAEL; SCHMIDT GUNTHER; DUCHENE GUY
权利人:SURTEES JOHN; BOUVY DIDIER; THOMAS ANTOINE; COMBRET YVES; FRANK MICHAEL; SCHMIDT GUNTHER; DUCHENE GUY; UCB SA
摘要:The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) n n n n n n n n n n Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.

专利号:US-10370409-B2
优先权日:2011-10-25
标题 :Synthesis of libraries of peptide tertiary amides
发明人:KODADEK THOMAS; GAO YU
权利人:SCRIPPS RESEARCH INST
摘要:The present disclosure is directed to a novel class of peptide-like oligomers called peptide tertiary amides (PTAs) and a combinatorial library of PTAs along with synthetic routes for the preparation of large combinatorial libraries of these compounds. The peptide tertiary amides provide an exceptional source of high affinity and selective protein ligands that are useful as tools for biological research and as drug leads, among others.

专利号:US-2014315831-A1
优先权日:2011-10-25
标 题:Synthesis of Libraries of Peptide Tertiary Amides

专利号:WO-2013063296-A1
优先权日:2011-10-25
标题 :Synthesis of libraries of peptide tertiary amides

专利号:US-9815842-B2
优先权日:2014-05-28
标题 :Pyrazolo pyrimidine derivatives and their use as MALT1 inhibitors
发明人:SOLDERMANN CAROLE PISSOT; QUANCARD JEAN; SCHLAPBACH ACHIM; SIMIC OLIVER; TINTELNOT-BLOMLEY MARINA; ZOLLER THOMAS
权利人:SOLDERMANN CAROLE PISSOT; QUANCARD JEAN; SCHLAPBACH ACHIM; SIMIC OLIVER; TINTELNOT-BLOMLEY MARINA; ZOLLER THOMAS; NOVARTIS AG
摘要:The present invention describes new pyrazolo-pyrimidine derivatives which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.

专利号:EP-2771478-A1
优先权日:2011-10-25
标 题:Synthesis of libraries of peptide tertiary amides

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Mourad, A. K.; Czekelius, C., Science of Synthesis Knowledge Updates, (2011) 3, 86.
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