CAS: 770-10-5; Benzyltrichlorosilane

相似化合物

1833-31-4 104013-25-4 1261861-19-1

上下游产品

benzyl chloride benzylmagnesium chloride (chloromethyl)trichlorosilane benzenebenzyltrimethylsilane (be-α-Cl)SiCl3 benzyl triethoxysilane 1,1,3,3-tetraethoxy-1,3-dibenzyl-disiloxane

📜氯化苄置于六甲基磷酰三胺,Nickelocene 四氯化硅,1,1,2-三氯-1,2,2-三甲基二硅烷,1,2-二甲基-1,1,2,2-四氯二硅烷体系中,化学反应 24.0H,以40%的收率获得产物苄基三氯硅烷
参考文献:一步式区域特异性合成烯丙基硅烷-扩展至苄基硅烷
标题:一步式区域特异性合成烯丙基硅烷-扩展至苄基硅烷
摘要:烯丙基三氯硅烷是在工业甲基氯二硅烷馏分存在下,根据烯丙基氯与sicl 4和nicp 2 / Hmpa(催化剂)的反应,按照一步区域特异性方法制备的.类似地获得4个苄基三卤硅烷.
DOI:10.1016/s0040-4039(00)92798-9

专利信息

专利号:US-7344863-B2
优先权日:1998-03-13
标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules
发明人：LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT
权利人:INVITROGEN CORP
摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.

专利号:WO-9805658-A1
优先权日:1996-08-07
标 题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1h-imidazole and analogs thereof
发明人：RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
权利人:ALTEON INC
摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilizes a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

专利号:US-6451543-B1
优先权日:1998-08-31
标题:Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
发明人：KOCHENDOERFER GERD G; HUNTER CHRISTIE L; KENT STEPHEN B H; BOTTI PAOLO
权利人:GRYPHON SCIENCES
摘要:The present invention relates to methods and compositions for lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides that are incorporated in a lipid matrix. The invention is exemplified in production of a prefolded membrane polypeptide embedded within a lipid matrix via stepwise chemoselective chemical ligation of unprotected peptide segments, where at least one peptide segment is embedded in a lipid matrix. Any chemoselective reaction chemistry amenable for ligation of unprotected peptide segments can be employed. Suitable lipid matrices include liposomes, micelles, cell membrane patches and optically isotropic cubic lipidic phase matrices. Prefolded synthetic and semi-synthetic membrane polypeptides synthesized according to the methods and compositions of the invention also permit site-specific incorporation of one or more detectable moieties, such as a chromophore, which can be conveniently introduced during synthesis. The methods and compositions of the invention have multiple uses. For example, they can be used to assay ligand binding to membrane polypeptides and domains comprising a receptor, and thus are extremely useful for structure/function studies, drug screening/selection/design, and diagnostics and the like, including high-throughput applications. The methods and compositions of the invention are particularly suited for FRET analyses of previously inaccessible membrane polypeptides.

专利号:US-6376649-B1
优先权日:1998-12-18
标题 :Methods for the synthesis of α- hydroxy-β-amino acid and amide derivatives
发明人：SEMPLE JOSEPH E; LEVY ODILE E
权利人:CORVAS INT INC
摘要:Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives and alpha-ketoamide derivatives and novel derivatives made by these methods are provided. These methods involve reacting a N-terminally blocked (protected) aminoaldehyde with an isonitrile and a carboxylic acid to give an amino-alpha-acyloxy carboxamide. The acyloxy group may be removed to give the derivative. Alternatively the protecting group is removed and acyl shift occurs to give the derivative. These derivatives are useful in the synthesis of compounds such as peptidyl alpha-ketoamides and alpha-hydroxy-beta-carboxylic acid and amide derivatives. Certain of these compounds have been reported to have activity as inhibitors of proteases, such as serine proteases and cysteine proteases.

专利号:US-5856511-A
优先权日:1996-08-07
标题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole and analogs thereof
发明人：RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
权利人:ALTEON INC
摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilized a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

专利号:US-2007049757-A1
优先权日:2005-08-26
标题:Methods for the synthesis of substituted amino uracils
发明人：RIEGER JAYSON M; THOMPSON ROBERT
权利人:RIEGER JAYSON M; THOMPSON ROBERT
摘要:The invention provides novel methods of preparing substituted amino uracil compounds that can be employed as useful intermediates in the synthesis of various xanthines. Highly regioselective unsymmetrical amino uracils can be obtained using these methods which is a particular advantage over other existing methods.