CAS: 67-73-2; Fluocinolone Acetonide

上下游产品

CAS号3932-49-8 21-O-acetyl 1,2... | CAS号64-17-5 乙醇 | CAS号1217194-25-6 flu°Cinolone ac... | CAS号356-12-7 醋酸氟轻松 | CAS号1269666-10-5 flu°Cinolone ac... | CAS号106931-78-6 氟轻松丙酮-21-羧酸 | CAS号356-12-7 醋酸氟轻松 | CAS号13242-30-3 氟轻松酮缩醛21醛水合物

Delta皮质素烯乙酸酯置于吡啶,Potassium Permanganate,甲酸,高氯酸,乙酸异丙烯酯,N,N-二甲基乙酰胺,氢氟酸,Potassium Acetate,对甲苯磺酸,Sodium Hydroxide体系中,用 甲醇,二氯甲烷,水,N,N-二甲基甲酰胺,丙酮,乙腈 作为反应溶剂,化学反应 35.0H,反应生成 醋酸氟轻松
参考文献:氟轻松的改进合成及6α,9α-氟化反应工艺研究
标题:氟轻松的改进合成及6α,9α-氟化反应工艺研究
摘要:从 21-乙酰氧基-17α-羟基-4,9(11)-二烯-3,20-二酮 (1A) 开发了一种高效,改进的氟轻松与生物发酵相结合的合成路线.研究了 6α 和 9α 氟化步骤的过程,观测到 6α 氟化的立体选择性高度依赖于底物.在对氟化试剂和活化试剂进行广泛筛选后,6α-F 以 85% 的收率和 98.9% 的立体选择性引入.代替 Hf 气体,在 9α 氟化步骤中应用 Hf 水溶液,以 89% 的收率提供所需的产物.从 1A 开始,氟轻松分 9 个步骤制备,总产率为 38.5%.
DOI:10.1246/cl.170923

专利信息

专利号:WO-2025125181-A1
优先权日:2023-12-14
标题:Green hydrogen, synthesis gas with a reduced nitrogen content, and flue gas for the synthesis of ammonia and urea
发明人：GORVAL EVGENI
权利人:THYSSENKRUPP UHDE GMBH; THYSSENKRUPP AG
摘要:The invention relates to the synthesis of urea from ammonia and carbon dioxide, wherein the hydrogen required for ammonia synthesis is obtained both by steam reforming of feed natural gas (grey hydrogen) and by electrolysis of water using electricity from renewable energy sources (green hydrogen). As the proportion of green hydrogen increases, the amount of carbon dioxide formed in the synthesis gas during steam reforming is no longer sufficient for the synthesis of urea. Therefore, flue gas, which is formed during the combustion of a fuel gas composed of fuel natural gas and combustion air and which also contains carbon dioxide, is additionally used. The oxygen formed during the electrolysis of water is introduced into the flue gas, and the modified flue gas is fed to a secondary reformer; and/or the fuel natural gas is combusted together with combustion air and the oxygen formed during electrolysis. Excess nitrogen is preferably separated from the synthesis gas before it is used for the synthesis of ammonia.

专利号:EP-4353356-A1
优先权日:2022-10-14
标题:Bifunctional catalyst formulation for synthesis of dimethylether (dme) from waste carbon dioxide and hydrogen by one-step and the synthesis method thereof
发明人：SEKER EROL; ZAHIDOVA AYSEL; MUTLU VAHIDE NURAN; DELIISMAIL OZGUN; SARRAFI SAHIN; TUNCER BASAK
权利人:SOCAR TURKEY ARASTIRMA GELISTIRME VE INOVASYON A S; IZMIR YUKSEK TEKNOLOJI ENSTITUSU REKTORLUGU
摘要:This invention relates to bifunctional catalyst formulation for synthesis of dimethyl-ether (DME) from waste carbon dioxide (CO₂) and hydrogen (H₂) and the preparation method of this catalyst formulation. In the preparation method, aluminum oxide-silicon dioxide-copper oxide (Al₂O₃-SiO₂-CuO) catalyst mixture formulation is obtained by using the sol-gel method. The catalysts that are the subject of the invention are bifunctional and perform the synthesis of DME from CO₂ and H₂ in a single-step without forming unwanted byproduct of CH₄, and thus, the synthesis of DME can be done much simply and economically. In addition to this, the sol-gel method in the current invention yields the controlled crystallite size of the active component in the catalysts; thus, the active site loss problem due to uncontrolled growth of crystal sizes that occurs in traditional preparation methods is prevented. The catalyst mixture formulation weight percentages are 10%-90% Al2O₃, 10%-90% SiO₂ and 10%-90% CuO.

专利号:WO-2023073242-A1
优先权日:2021-11-01
标题:Process and apparatus for synthesis of organic carbon compounds
发明人：BECKER SEBASTIAN; NIEHOFF GUERRA ALEJANDRO; SCHACHT OLAF; HAID MICHAEL OLIVER
权利人:REFUEL GREEN CONSULTING & TECH GMBH
摘要:The invention relates to a process for synthesis of organic carbon compounds from feed gases containing carbon dioxide (CO2) and optionally hydrogen (H2) and also optionally short-chain hydrocarbons (CxHy). The invention aims to raise energetic efficiency significantly while achieving high degrees of chemical conversion. This is achieved by charging the reaction space (4) of the DBD reactor (1) with a liquid and a catalyst, establishing a temperature and pressure range in the reaction space (4), introducing the feed gases into the reaction space (4) of the DBD reactor (1), to form ascending gas bubbles in the reaction space (4), forming a non-thermal plasma in the ascending gas bubbles by applying a high AC voltage or a pulsed high voltage between the electrode/cathode (5) and a counter-electrode/anode (11) surrounding the outer wall (2), converting the constituents of the supplied feed gases into reaction products and reaction intermediates by endothermic reactions in the gas/plasma bubbles, preparing organic carbon compounds in exothermic reactions by means of one or more catalysts in the liquid phase after the diffusion of the reaction products/intermediates into the liquid phase, by utilizing the liquid in the electrical discharge space of the DBD reactor additionally for exothermic thermocatalytic synthesis reactions in the liquid phase, including all the phase interfaces, using a catalyst, and withdrawing/discharging the reaction products prepared, such as hydrocarbons, in a product stream (12) from the DBD reactor.

专利号:US-2025197362-A1
优先权日:2022-03-15
标 题:Process for the synthesis of melamine
发明人：GAMBA SIMONE; FILIPPI ERMANNO
权利人:CASALE SA
摘要:A process for the high-pressure non-catalytic synthesis of melamine from urea wherein various heat inputs of the process are provided electrically, the process comprises reacting urea to form melamine in a synthesis reactor provided with electrical heating elements, the process further comprises heating the melamine melt electrically during transport and/or using electrically produced heat to remove water from melamine crystals.

专利号:US-2012178710-A1
优先权日:2009-07-01
标题 :Synthesis of cyclic diguanosine monophosphate and thiophosphate analogs thereof
发明人：JONES ROGER A; GAFFNEY BARBARA L
权利人:JONES ROGER A; GAFFNEY BARBARA L; UNIV RUTGERS
摘要:The invention provides methods for the synthesis of cyclic dinucleotides and thiophosphate analogs thereof as well as a new family of analogs of cyclic diguanosine monophosphate that includes a series of seven phosphorothioate derivatives that includes diastereomers of mono-, di-, and trithiophosphates.

专利号:US-12391691-B2
优先权日:2018-11-16
标题:Synthesis of key intermediate of KRAS G12C inhibitor compound
发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as