CAS: 24424-95-1; Di-Tert-Butyl Tricarbonate

该化合物是有机合成中通常用作试剂的有机化合物,特别是用于保护酒精和氨;其特征特征为散装叔丁基化合物,具有不动性障碍,成为选择性保护剂;该化合物一般无色可粉黄黄色液体或固体,视温度和纯度而定;在正常条件下相对稳定,但在接触湿度或热量时可分解,释放二氧化碳;二乙基三碳酸酯在二氯甲烷和乙基乙酸酯等有机溶剂中可溶解,但在水中不可溶解;其活性允许形成稳定的碳酸酯酯,可在温和的条件下有选择地去除,使其在多步有机合成中具有价值;在处理该化合物时,应采取安全防范措施,因为它可能会引起皮肤和眼睛的刺激,并应保持适当的储存条件以防止降解.

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        专利信息


        专利号:US-4515920-A
        优先权日:1984-04-30
        标题 :Synthesis of peptides and proteins
        发明人:ERICKSON BRUCE W
        权利人:UNIV ROCKEFELLER
        摘要:Solid phase synthesis of peptides and proteins have been improved by the use of a trifunctional segment, one functional group of which is bound to a solid support, the other two functional groups being available as substrates upon which identical proteins are synthesized.

        专利号:US-9650355-B2
        优先权日:2013-01-31
        标 题 :Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure
        发明人:HAM JUNGYEOB; KIM TAE JUNG; KWON HAK CHEOL; JEONG KYU HYUK; SONG JUNGHO; CHUNG BONG CHUL
        权利人:KOREA INST SCI & TECH
        摘要:The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constructed first and an aryl group may be introduced at the final stage. Through this, various kinds of derivatives that could not be prepared from the existing methods can be synthesized effectively. Further, the synthesis method according to the present disclosure is appropriate for large-scale production.

        专利号:EP-1567195-B1
        优先权日:2002-11-26
        标题 :Dendrimer conjugates for selective solubilisation of protein aggregates
        发明人:HEEGAARD PETER; BOAS ULRIK
        权利人:UPFRONT CHROMATOGRAPHY AS
        摘要:Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates ar effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.

        专利号:US-2010047841-A1
        优先权日:2007-02-27
        标 题 :Synthesis of desacetoxytubulysin h and analogs thereof
        发明人:WIPF PETER; WANG ZHIYONG
        权利人:UNIV PITTSBURGH
        摘要:Compounds of formula I, XVI and XXI possess potent cell growth inhibitory activity. These compounds are described have therapeutic utility, particularly in the treatment of cancer as well as conditions and disorders related to uncontrolled cell growth: n n n n n n n n n n wherein the variables R 1 , R 2 , R 3 , R 4 , R 5 , X, Y and Z are described herein.

        专利号:WO-2008106080-A2
        优先权日:2007-02-27
        标 题 :Synthesis of desacetoxytubulysin h and analogs thereof

        专利号:CN-112521285-B
        优先权日:2020-12-03
        标题 :Synthesis process of di-tert-butyl dicarbonate

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        合成参考文献


        摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 193.
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