CAS: 23444-65-7; Alkannin

该化合物是天然生成的环丙酮化合物,主要产自Alkana锡托工厂(俗称alkanet)的根,其特点是深红至紫色,在各种应用中,包括在化妆品和食品产品中,它是一种有价值的染色物;Alkannin展示了抗氧化物特性,并研究过其潜在的治疗作用,包括防炎和抗微生物活动;该化合物溶解于有机溶剂,但溶解性有限;其化学结构具有环环环的环状,具有氢氧基和碳基,有助于其再活性和生物活动;Alkanninin经常用于传统医学,并因潜在的健康利益而引起现代药理学的兴趣;由于其天然来源和生物活性特性,它被认为是在天然产品化学和药用药剂领域进一步研究的有希望对象.

结构式图片

合成工艺路线路线简述

    📜Shikonin,Alkannin 在 苯体系中,获得 Alkannin
    参考文献:Brokmann,Justus Liebigs Annalen Der Chemie,1936,Vol. 521,P. 1,2,11,19,34
    标题:Brokmann,Justus Liebigs Annalen Der Chemie,1936,Vol. 521,P. 1,2,11,19,34

    海关参考信息

    专利信息


    专利号:WO-2023203374-A1
    优先权日:2022-04-20
    标 题 :[1,2]selenazolo[2,3-a]pyridin-8-ium inhibitors of pyruvate kinase isoform m2
    发明人:ARSENJANS PAVELS; DIMITRIJEVS PAVELS; MAKRECKA-KUKA MARINA
    权利人:LATVIAN INST ORGANIC SYNTHESIS
    摘要:The present invention relates to a novel isoselenazolopyridinium salts as anticancer agents by inhibiting pyruvate kinase isoform M2 (PKM2) activity, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment of various diseases and disorders by administration of such substances.

    专利号:US-9987208-B2
    优先权日:2013-04-04
    标题 :Elastin synthesis/regeneration promoting agent
    发明人:NISHIZAKI TOMOYUKI; TANAKA AKITO
    权利人:NISHIZAKI BIOINFORMATION RES INSTITUTE
    摘要:8-[2-(2-Pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) has an action to promote synthesis and regeneration of elastin, and is useful as an agent for the prophylaxis or improvement of wrinkles, and an anti-aging drug.

    专利号:US-11517541-B2
    优先权日:2017-04-20
    标 题:Applications of spermidine and its derivatives
    发明人:ZHU WEI; PAN WUGUANG
    权利人:GENEHEAL BIOTECHNOLOGY CO LTD
    摘要:Disclosed are applications of spermidine or its pharmaceutically acceptable derivatives. The inventors performed calculation and analysis using software based on existing data relating to protein and small-molecule structures, and screened out compounds which can effectively interfere with the activity of PAWS and thus reduce SAICAR synthesis, thereby achieving the goal of treating or improving tumors. It is expected to produce better effect in the treatment or improvement of tumors.

    专利号:KR-102686376-B1
    优先权日:2022-09-01
    标 题 :Carbon quantum dots based on by-products of gromwell root and a method for synthesis of carbon quantum dots based on by-products of gromwell root

    专利号:CN-101407783-A
    优先权日:2008-11-26
    标 题 :A method of using rare earth elements to promote the synthesis of shikonin in yunnanensis yunnanensis cells

    专利号:CN-102851347-A
    优先权日:2012-07-13
    标题 :Novel use of hydrogen sulfide to promote the synthesis of secondary metabolites

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s00894-011-1170-9
    摘要:Jin R, Bai Y. Theoretical investigation of the radical scavenging activity of shikonin and acylshikonin derivatives. Journal of Molecular Modeling. 2011 Jul 15;18(4):1401–8. doi: 10.1007/s00894-011-1170-9.
    参考文献:10.1155/2011/165852
    摘要:Haghbeen K, Pourmolaei S, Mareftjo MJ, Mousavi A, Akbari Noghabi K, Hosseini Shirazi F, Meshkat A. Detailed Investigations on the Solid Cell Culture and Antimicrobial Activities of the Iranian Arnebia euchroma. BioMed Research International. 2011 Jan;2011(1). doi: 10.1155/2011/165852.
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