CAS: 17609-47-1; (S)-Ethyl 2-Amino-3-Methylbutanoate Hydrochloride

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Cyclo(-L-Val-L-Ala-)置于盐酸,正丁基锂体系中,用 二氯甲烷 用作溶剂,化学反应 63.83H,反应生成L-缬氨酸乙酯盐酸盐
参考文献:Weihrauch,Thomas; Leibfritz,Dieter,Liebigs Annalen Der Chemie,1985,# 9,P. 1917-1921
标题:Weihrauch,Thomas; Leibfritz,Dieter,Liebigs Annalen Der Chemie,1985,# 9,P. 1917-1921

专利信息

专利号:US-9328061-B2
优先权日:2012-03-01
标题:Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols
发明人：HOVEYDA AMIR H; SILVERIO DANIEL L; PILYUGINA TATIANA; TORKER SEBASTIAN; ROBBINS DANIEL
权利人:TRUSTEES BOSTON COLLEGE
摘要:The present invention provides organic molecules and methods thereof for reactions between organoboron reagents and double bonds, such as imines or carbonyls, to stereoselectively provide chiral products including amines and alcohols, entities useful for the preparation of biologically active molecules.

专利号:US-6495693-B2
优先权日:1996-11-22
标题:N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; FOLMER BEVERLY K; JOHN VARGHESE; LATIMER LEE H; NISSEN JEFFREY S; PORTER WARREN J; THORSETT EUGENE D; WU JING
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-2015057451-A1
优先权日:2012-03-01
标 题 :Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols

专利号:WO-2013131043-A1
优先权日:2012-03-01
标 题:Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols

专利号:US-6096782-A
优先权日:1996-11-22
标 题:N-(aryl/heteroaryl) amino acid derivatives pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds

专利号:JP-2001503782-A
优先权日:1996-11-22
标题 :Method and compound for inhibiting release of beta-amyloid peptide and / or its synthesis