CAS: 16858-02-9; N1,N1,N2,N2-Tetrakis(Pyridin-2-Ylmethyl)Ethane-1,2-Diamine

相似化合物

189440-33-3 80384-94-7 136768-57-5

上下游产品

N,N'-二-2-吡啶甲基乙二胺 N,N'-Bis(2-Pyridylmethyl)Ethylenediamine 4608-34-8

📜N,N'-二(2-吡啶亚甲基)乙二胺置于sodium Hydroxide,Sodium Tetrahydroborate,四乙基溴化铵体系中,用 乙醇,二氯甲烷,水 用作溶剂,化学反应 243.0H,反应生成N,N,N,N-四-(2-吡啶基甲基)乙二胺
参考文献:Chromium(III) Complexes Of The Hexadentate Ligand N,N,N',N'-Tetrakis(2-Pyridylmethyl)Ethane-1,2-Diamine. Synthesis,Structure And Reactivity.
标题:Chromium(III) Complexes Of The Hexadentate Ligand N,N,N',N'-Tetrakis(2-Pyridylmethyl)Ethane-1,2-Diamine. Synthesis,Structure And Reactivity.
摘要:Chromium(III) Complexes Of N,N,N',N'-Tetrakis(2-Pyridylmethyl)Ethan-1,2-Diamine,Tpen,Have Been Synthesised By Air Oxidation Of Chromium(II) Acetate And The Ligand In A Methanol-Water Mixture. Addition Of Perchlorate Precipitates [cr(Tpen)(ococh3)](Clo4)(2). H2O,Which Has Been Used As The Starting Material For The Synthesis Of A Number Of Complexes Including [cr(Tpen)](Clo4)(3),[cr(Tpen)(Oh)](Clo4)(2) And Cis-[cr(Tpen)(Oh)(2)]Clo4. 3H(2)O. These Compounds Have All Been Characterised By Single-Crystal Structure Determinations. The Four Complexes Are All Monomeric And Contain Six-Coordinate Chromium(III) Cations. In [cr(Tpen)](3+) All Six Nitrogens Of The Potentially Hexadentate Tpen Ligand Are Coordinated To Chromium,In [cr(Tpen)(ococh3)](2+) And [cr(Tpen)(Oh)](2+) Five Nitrogen Atoms Are Coordinated And In Cis-[cr(Tpen)(Oh)(2)](+) Only Four Nitrogen Atoms Are Coordinated. The Remaining Coordination Sites In The Last Three Cations Are occupied By Oxygen Atoms Of The Acetate And The Hydroxide Ligands. In Neutral Solution The Divalent Base [cr(Tpen)(Oh)](2+) Is Relatively Stable,But Acidification Leads To A Fast Equilibration Reaction Between [cr(Tpen)(Oh2)](3+) And [cr(Tpen)](3+),Which Has Been Characterized By Stopped-Flow Measurements. In Basic Aqueous Solution [cr(Tpen)(Oh)](2+) Reacts Slowly To Give Cis-[cr(Tpen)(Oh)(2)](+). Acidification Of Cis-[cr(Tpen)(Oh)(2)](+) Solutions Leads To The Same Hexaamine/pentaamine Equilibrium Mixture But By A Considerably Slower Process. Part Of This Significant Reactivity Difference May Be Attributed To The Conformation Of The Coordinated Part Of The Ligand,Which Is Similar In The Hexaamine And Pentaamine Complexes,And Markedly Different In The Tetraamine Complex.
Doi:10.3891/acta.Chem.Scand.53-1083

专利信息

专利号:US-2023002805-A1
优先权日:2021-06-25
标 题 :Use of organic cationic compounds to accelerate nucleic acid hybridization, synthesis, and amplification
发明人：RABBANI ELAZAR; COLEMAN JACK
权利人:ENZO BIOCHEM INC
摘要:The invention provides methods for accelerated synthesis of nucleic acids, and related compositions which involve the use of organic amines in the nucleic acid synthesis reaction mixture. The invention also provides methods for reducing processing steps associated with nucleic acid synthesis. The invention further provides methods for screening compounds that have positive benefits on the synthesis of nucleic acids.

专利号:US-2019323050-A1
优先权日:2016-12-21
标题 :Modulation of Enzymatic Polynucleotide Synthesis Using Chelated Divalent Cations
发明人：GRISWOLD JR KETTNER JOHN FREDERICK; LEE HOWON; CHURCH GEORGE M
权利人:HARVARD COLLEGE
摘要:Methods and apparatus of modulating polynucleotide synthesis are provided. The methods include delivering reagents comprising enzymes, nucleotides and ions to oligonucleotide primers wherein the reagents catalyze incorporation of the nucleotides to 3′ ends of the oligonucleotide primers, and modulating incorporation of the nucleotides to the 3′ ends of the oligonucleotide primers. Polynucleotide synthesis is modulated by modulating presence or absence of catalytic cation cofactors to provide sequence defined synthesis of polynucleotides. In certain embodiments, the polynucleotides encode information.

专利号:US-12053529-B2
优先权日:2018-08-01
标题:Amino-reactive positively charged ATRP initiators that maintain their positive charge during synthesis of biomacro-initiators
发明人：RUSSELL ALAN J; MURATA HIRONOBU
权利人:UNIV CARNEGIE MELLON
摘要:Provided herein are materials and methods that include utilizing atom transfer radical polymerization (ATRP) initiator molecules that maintain a positive charge during biomacro-initiator synthesis.

专利号:US-9777082-B2
优先权日:2011-10-05
标题 :Synthesis of hyperbranched polyacrylates by emulsion polymerizsation of inimers
发明人：PUGH COLEEN; GARCIA GUILLERMINA
权利人:UNIV AKRON
摘要:A method for the production of hyperbranched polyacrylates includes the step of reacting acrylic inimers through controlled living polymerization in aqueous conditions. The inimers may have the formula: n nWherein X is a halogen, a thiocarbonylthio or nitroxide group, and R is hydrogen, methyl, dodecyl, and groups containing mesogenin substituents, fluorocarbon substituents, siloxane substituents and oxyethylene substituents. In particular, the aqueous condition is emulsion or miniemulsion. The polymerization may be reverse ATRP, SN&RI and AGET polymerization or RAFT polymerization (with thiocarbonylthio X groups) or nitroxide mediated polyeization (with nitroxide X groups).

专利号:US-6733828-B2
优先权日:2002-01-29
标 题 :Method of fabricating nanostructured materials
发明人：CHAO KUEI-JUNG; YANG CHIA-MIN
摘要:A method of confined synthesis of nanostructured material inside a mesoporous material. The method includes the step of providing mesoporous material having uniform and ordered mesopores. Next, a monolayer of charged functional group is attached on the pore surface of mesoporous host material by reacting with functional molecule. A oppositely-charged molecule is incorporated into the confined space of mesoporous material by either ion exchange or incipient wetness impregnation. Finally, the incorporated molecule is reduced or oxidized or further reacted with secondarily-incorporated molecule to form nanostructured material in mesoporous material.

专利号:US-2009325858-A1
优先权日:2003-03-21
标 题:Reduction of Zinc-Induced Neurotoxic Injury By Blockade of Nitric Oxide Synthesis
发明人：FREDERICKSON CHRISTOPHER J
权利人:ANDRO DIAGNOSTICS INC
摘要:The present invention provides methods of inhibiting release of zinc from neurons and of preventing zinc-mediated brain injury. Also provided are methods of improving cerebral blood flow while preventing zinc-mediated brain injury. Inhibitors of or activators of nitric oxide synthases modulate nitric oxide synthesis to reduce nitric oxide-induced release of neurotoxic amounts of zinc, thereby reducing zinc-mediated neuronal injury after brain trauma.