CAS: 1583-67-1; 3-Fluorophthalic Acid

上下游产品

CAS号443-82-3 3-氟-1,2-二甲苯 | CAS号321-38-0 1-氟萘 | CAS号652-39-1 3-氟邻苯二甲酸酐 | CAS号87-59-2 2,3-二甲基苯胺 | CAS号455-38-9 间氟苯甲酸 | CAS号2211-82-7 7-氟异苯并呋喃-1(3H)-酮 | CAS号652-39-1 3-氟邻苯二甲酸酐 | CAS号160485-42-7 [3-fluoro-2-(hy... | CAS号61864-48-0 4-fluoro-2-meth...

3-硝基邻苯二甲酸酐置于potassium Fluoride,氯化亚砜体系中,用 环丁砜 用作溶剂,化学反应 4.0H,以0.66 G的收率获得3-氟邻苯二甲酸
参考文献:一种3-氟邻苯二甲酸的合成方法
标题:一种3-氟邻苯二甲酸的合成方法
摘要:本发明公开了一种3‑氟邻苯二甲酸的合成方法,将原料3‑硝基邻苯二甲酸溶解通过乙酰氯溶剂进行脱水,脱水后通过氟化钾进行脱硝氟代,再加入二氯亚砜除去氟代过程中产生的副产物,提纯后得到目标化合物3‑氟邻苯二甲酸.本发明以3‑硝基邻苯二甲酸作为合成3‑氟邻苯二甲酸的原料,原料廉价易得,工艺简单,收率高;通过调节ph的方法,将产物从环丁砜溶剂中很好的分离出来,解决了溶剂沸点高不易蒸发出来的难点;采用乙酰氯作为脱水溶剂,不仅取代了管制药品乙酸酐,而且减少了乙酸酐脱水过程中带来的副产物乙酸,反应条件温和且后处理简单方便.

专利信息

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.

专利号:US-11884714-B2
优先权日:2019-03-01
标 题:Cyclic peptide analogs of melanocortin and amanitin and methods of making such
发明人：PERRIN DAVID; TODOROVIC MIHAJLO; BÉNARD FRANÇOIS; ZHANG CHENGCHENG
权利人:UNIV BRITISH COLUMBIA; PROVINCIAL HEALTH SERVICES AUTHORITY
摘要:The invention described herein is based in part on the discovery of a protein/peptide crosslink, which introduces fluorescent properties, and which has been applied to synthesize analogues of melanocortin and amanitin as choice peptides to be explored in the context of isoindole peptides. Without limitation, it is expected that those trained in the art of peptide synthesis and stapling would appreciate the consequences of this invention such that other peptides of varied length can be similarly constrained by isoindole staples as featured herein.

专利号:US-5663449-A
优先权日:1989-05-19
标 题 :Intermediate compounds in the synthesis of heteroarylpiperidines, pyrrolidines and piperazines

专利号:US-5637710-A
优先权日:1989-05-19
标题:Intermediate compounds in the synthesis of heteroarylpiperidines and piperazines

专利号:US-6770586-B2
优先权日:2000-04-24
标题 :Solid catalyst component and catalyst for olefins polymerization
发明人：TASHINO KUNIHIKO; SUZUKI YUKIHIRO; NISHIYAMA ISA; OGAWA HAYASHI; YOSHIDA TAKUMA; HOSAKA MOTOKI; SATO MAKI
权利人:TOHO TITANIUM CO LTD
摘要:Solid catalyst components and catalysts which contain (a) magnesium compound, (b) titanium tetrachloride, and (c) a phthalic acid diester or its derivative are useful in the synthesis of olefin polymers in high yields. Particularly, propylene polymers can be obtain in very high yields while retaining high stereoregularity.