CAS: 139911-29-8; 2-Methyl-4-Fluorophenylboronic Acid

上下游产品

CAS号5419-55-6 硼酸三异丙酯 | CAS号452-63-1 2-溴-5-氟甲苯 | CAS号7732-18-5 水 | CAS号121-43-7 硼酸三甲酯 | CAS号106-93-4 1,2-二溴乙烷 | CAS号343-43-1 2-氟芴 | CAS号673456-16-1 2-溴甲基-4-氟苯硼酸新戊二醇酯

硼酸三异丙酯,2-溴-5-氟甲苯置于正丁基锂体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 2.0H,以61.5%的收率获得4-氟-2-甲基苯硼酸
参考文献: Process For Preparation Of Tavaborole[fr] Procédé De Préparation De Tavaborole
标题: Process For Preparation Of Tavaborole[fr] Procédé De Préparation De Tavaborole
摘要:本发明涉及一种制备高纯度塔伐硼酮的方法.本发明涉及一种评估塔伐硼酮纯度的方法.

专利信息

专利号:US-12428425-B2
优先权日:2020-05-04
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; PANTELEEV JANE; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.