CAS: 13931-83-4; Chloronickel

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      专利号:WO-2022036662-A1
      优先权日:2020-08-21
      标题:Method for enzymatic synthesis of 3-hydroxybutyrate
      发明人:FAN WENCHAO; GAO SHULIANG; WANG JINGANG; LIANG YAN; YANG HAIFENG; REN LIANG; Yuan shenglun
      权利人:ZHEJIANG HUARUI BIOTECHNOLOGY CO LTD
      摘要:Provided is a method for the enzymatic synthesis of 3-hydroxybutyrate. According to the method, acetoacetate is taken as a substrate, and a reduction reaction is catalyzed with an alcohol dehydrogenase of SEQ ID No:1 or a mutant thereof of SEQ ID Nos:3-27, to obtain 3-hydroxybutyrate.

      专利号:WO-2023198025-A1
      优先权日:2022-04-11
      标题:Synthesis method and synthesis device for organic nitrogen-containing compound
      发明人:LI GUANGQIN; Liao Peisen; XIAN JIAHUI; LI SUISHENG; ZHANG YAWEI
      权利人:UNIV SUN YAT SEN
      摘要:The present invention relates to the field of organic synthesis, specifically to a synthesis method and synthesis device for an organic nitrogen-containing compound. Provided in the present invention is a synthesis method for an organic nitrogen-containing compound. In the method provided in the present invention, a porous carbon material is used as a catalyst, organic nitrogen-containing compounds such as an oxime, an amine, a nitrile and an amino acid are synthesized by means of an electro-catalysis method, byproducts are unlikely to generate, and the method is safe and environmentally friendly. Experiments show that organic nitrogen-containing compounds such as an amino acid, an oxime, an amine and a nitrile are successfully synthesized by using the method of the present invention, and the method has good Faraday efficiency and yield. In the present application, the synthesis of the above organic nitrogen-containing compounds can be realized by using nitrogen oxide waste gas or waste water as a raw material; and by converting the nitrogen oxide waste gas or waste water, the utilization of waste is realized, and the benefits are maximized. Further provided in the present invention is a synthesis device for an organic nitrogen-containing compound, which device is used for solving the defects of high energy consumption, long consumption time, and complex product separation and purification of existing synthesis methods.

      专利号:WO-2024116112-A1
      优先权日:2022-12-01
      标题 :Direct synthesis of l10 feni and other metal alloys from metal-cyano/nitrosyl complexes
      发明人:CAPOBIANCHI ALDO; VARVARO GASPARE; IMPERATORI PATRIZIA
      权利人:CONSIGLIO NAZIONALE RICERCHE
      摘要:An effective and easily scaled-up chemical synthesis route to obtain L1 0 Iron-Nickel alloy from cyano/nitrosyl-metal complex precursor salts, for sustainable permanent magnets free of crittical rare-earth elements, with a (BH) max ranging in between that 5 of hexaferrites (up tO ~45 kJ/m 3 ) and rare-earth-based permanent magnets (up to ~500 kJ/m 3 ).

      专利号:WO-2022173135-A1
      优先权日:2021-02-10
      标题:Recombinant microorganism with improved production capacity of heme, coproporphyrin â…², uroporphyrin â…², zinc-coproporphyrin â…², zinc-uroporphyrin â…², and biliverdin, and method for production of heme, coproporphyrin â…², uroporphyrin â…², zinc-coproporphyrin â…², zinc-uroporphyrin â…², and biliverdin by using same
      发明人:HAN SUNG OK; KO YOUNG JIN
      权利人:UNIV KOREA RES & BUS FOUND
      摘要:The present invention relates to a recombinant microorganism with improved production capability of heme, coproporphyrin â…¢, uroporphyrin â…¢, zinc-coproporphyrin â…¢ (Zn-coproporphyrin â…¢), zinc-uroporphyrin â…¢ (Zn-uroporphyrin â…¢), and biliverdin, a preparation method therefor, and a method for production of heme, coproporphyrin â…¢, uroporphyrin â…¢, zinc-coproporphyrin â…¢, zinc-uroporphyrin â…¢, and biliverdin by using same. In the present invention, a synergistic effect of the introduction of genes related to the C4 and C5 pathways for synthesis of 5-aminolevulinic acid (ALA), genes related to the coproporphyrin â…¢-dependent pathway, and transcriptional regulatory factors was first evidenced through the improved porphyrin productivity effect of the recombinant microorganism. In addition, in contrast to the conventional recombinant microorganisms which are induced for extracellular production by introducing an extracellular secretion protein thereinto, the present invention first identified that the extracellular secretion of heme can be remarkably increased through the strategy of modifying microorganism cell walls. The recombinant microorganism according to the present invention is provided with enhanced production capability of porphyrin-based materials through the aforementioned metabolism engineering strategy and exhibits high productivity therefor. Thus, heme, coproporphyrin â…¢, uroporphyrin â…¢, zinc-coproporphyrin â…¢, zinc-uroporphyrin â…¢, and biliverdin, which are all high value-added materials, can be economically and efficiently produced by using the recombinant microorganism of the present invention.

      专利号:WO-2024255690-A1
      优先权日:2023-06-13
      标 题 :Genetically engineered bacterium for producing d-pantothenic acid, construction method therefor and use thereof
      发明人:ZHANG BO; HE ZHOULIN; LIU ZHIQIANG; Tang Mengna; XIAO YUNYING; SHEN PAN; ZHENG YUGUO
      权利人:UNIV ZHEJIANG TECHNOLOGY
      摘要:A genetically engineered bacterium that produces D-pantothenic acid and a construction method therefor, and the use of the engineered bacterium in the preparation of D-pantothenic acid by means of microbial fermentation. In the present invention, mainly by means of: (1) increasing the copy number of key genes in the pantoic acid synthesis pathway in Escherichia coli organisms to further make carbon flux flow to the synthesis of D-pantothenic acid, and (2) in order to keep enhancing the flow of carbon flux to the synthesis of D-pantothenic acid, negatively regulating a transcription factor by means of weakening the nitrogen limitation and activating glycolytic front-end genes to pull the carbon flow so as to save phosphoenolpyruvic acid and reduce the central carbon flow that enters TCA, an engineered strain for producing D-pantothenic acid with no plasmid or antibiotic addition is obtained. Finally, the titer of D-pantothenic acid in the shake flask is increased by 87.2% compared to that of the starting strain, and reaches 5.43 g/L. After fermentation in a 5-L fermentation tank for 84 hours, the yield of D-pantothenic acid can reach 94.2 g/L.

      专利号:US-11920171-B1
      优先权日:2016-05-06
      标题:Synthesis and oxidation of methane
      发明人:MANSOORABADI STEVEN
      权利人:UNIV AUBURN
      摘要:The present disclosure describes genes and proteins of the coenzyme F430 synthetic pathway. The genes and proteins in the pathway find uses as isolated nucleic acids, transformation vectors, a transformation media, genetically modified cells, methods of modulating methanogenesis, methods of modulating methane oxidation, methods of making a tetrapyrrole compound, methods of oxidizing methane, methods of biogenic methane synthesis is provided, methods of assaying an organism for potential methanogenic or methanotrophic activity, and isolated proteins.

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      合成参考文献


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