CAS: 82-07-5; Xanthene-9-Carboxylic Acid

该化合物是一种多用途有机化合物,其特性是Xanthene核心在9点方位上与一个箱式酸组一起发挥作用,这种结构具有独特的光物理和化学特性,在荧光染色,分子探测器和有机合成中间体等应用中具有价值,其硬性多环框架增强了稳定性,而碳箱酸混合物允许进一步衍生或融化.该化合物特别有助于开发对PH敏感的荧光材料,并成为高级功能分子的构件.高纯度可用于满足严格的研究和工业要求,确保敏感应用的再生性.

英文名称Xanthene-9-Carboxylic Acid
中文名称呫吨-9-甲酸
IUPAC名称9H-xanthene-9-carboxylic acid
其它别名Xanthanoic Acid; Xanthene-9-Carboxylic Acid, ; Xanthene- 9- Carboxylic Acid; 9-Xanthenylcarboxylic Acid; Xanthine-9-Carboxylic Acid; Unii-63A81F6A8V; 9-Xanthenecarboxylic Ac
CAS编号82-07-5
MFCD编号:MFCD00005059
EINECS号:201-394-9
FDA UNII编号:63A81F6A8V
分子式:C14H10O3
分子量:226.23
产品CID: 2365412
产品分类化学试剂 → 有机试剂 → 三环化合物

相似结构搜索
产品信息参考;;;;
InChIKey: VSBFNCXKYIEYIS-UHFFFAOYSA-N
InChI=1S/C14H10O3/c15-14(16)13-9-5-1-3-7-11(9)17-12-8-4-2-6-10(12)13/h1-8,13H,(H,15,16)…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
严重眼刺激类别2A
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P264-P271-P280-P302+P352-P305+P351+P338
UN编号2811
危险品标志Xi
安全声明26-36-37/39-37
危险类别码36/37/38
WGK Germany3.0

欧盟法规

ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

合成目标产物 Xanthene-9-Carboxylic Acid 主要起始原料 Xanthene-9-Carbonitrile
85554-24-1 = 82-07-5 [标题:Reaction Conditions
标题:9-Xanthenecarboxylic Acid
参考文献:Romania]

5813-90-1 = 82-07-5
反应条件:1.1 Reagents: Isoamyl Nitrite Solvents: Acetic Acid; 24 H,Rt -> 80 °C
标题:Amyl Nitrite-Mediated Conversion Of Aromatic And Heteroaromatic Primary Amides To Carboxylic Acids
作者:Potter,Garrett T.; Et Al
参考文献:Tetrahedron Letters 日期:2015 卷标:56(37) 页码:5153-5156]

90-46-0 = 82-07-5 [标题:Reaction Conditions
标题:9-Xanthenecarboxylic Acid
参考文献:Romania]

90-47-1 = 82-07-5
反应条件:1.1 Reagents: (Dimethyl Sulfide)Trihydroboron Solvents: Tetrahydrofuran; 1 H,75 - 80 °C1.2 Reagents: Hydrochloric Acid,Sodium Chloride Solvents: Water2.1 Reagents: Butyllithium,N,N,N′,N′-Tetramethylethylenediamine Solvents: Tetrahydrofuran,Hexane; -78 °C; 10 Min,-78 °C2.2 -78 °C; -78 °C -> Rt; 20 Min,Rt
标题:High-Fidelity Dimerization Of Xanthenyl Radicals And Dynamic Qualities Of A Congested Ethane: Diethyl Dixanthenyl-9,9'-Dicarboxylate
作者:Hogan,David T.; Et Al
参考文献:European Journal Of Organic Chemistry 日期:2022 卷标:2022(1)]

92-83-1 = 82-07-5
反应条件:1.1 Reagents: Butyllithium,N,N,N′,N′-Tetramethylethylenediamine Solvents: Tetrahydrofuran,Hexane; -78 °C; 10 Min,-78 °C1.2 -78 °C; -78 °C -> Rt; 20 Min,Rt
标题:High-Fidelity Dimerization Of Xanthenyl Radicals And Dynamic Qualities Of A Congested Ethane: Diethyl Dixanthenyl-9,9'-Dicarboxylate
作者:Hogan,David T.; Et Al
参考文献:European Journal Of Organic Chemistry 日期:2022 卷标:2022(1)]

92-83-1 = 82-07-5
反应条件:1.1 Reagents: Potassium Carbonate,N,N′-Methanetetraylbis[benzenamine] Solvents: Dimethyl Sulfoxide
标题:The Carboxylation Of Active Methylene Compounds With Diphenylcarbodiimide And Potassium Carbonate
作者:Chiba,Koji; Et Al
参考文献:Chemistry Letters 日期:1990 卷标:(1) 页码:39-42]

= 82-07-5
反应条件:1.1 Reagents: Tert-Butyl Nitrite Solvents: Water; 35 Min,29 °C
标题:Tert-Butyl Nitrite-Mediated Synthesis Of N-Nitrosoamides,Carboxylic Acids,Benzocoumarins,And Isocoumarins From Amides
作者:Yedage,Subhash L.; Et Al
参考文献:Journal Of Organic Chemistry 日期:2017 卷标:82(11) 页码:5769-5781

氧杂蒽置于正丁基锂,乙醚体系中,化学反应生成呫吨-9-甲酸
参考文献:Antispasmodics. Ii. Basic Esters Of Some Polynuclear Carboxylic Acids1
标题:Antispasmodics. Ii. Basic Esters Of Some Polynuclear Carboxylic Acids1
摘要:
DOI:10.1021/ja01248A038

海关参考信息

2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
2915110000-甲酸
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2008125587-A1
优先权日:2006-05-25
标题 :Synthesis of triazole compounds that modulate HSP90 activity
发明人：CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
权利人:CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
摘要:The present invention provides novel methods of preparing triazole compounds which inhibit the activity of Hsp90. One embodiment of the invention is directed to methods for preparing a triazole compound represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising the steps of: a) reacting an amide represented by the following Structural Formula: n n n n n n n n n n with a thionation reagent to form a thioamide; b) reacting the thioamide of step a) with hydrazine to form a hydrazonamide; c) reacting the hydrazonamide of step b) with a carbonylation or a thiocarbonylation reagent. n In one embodiment, the present invention is a method of synthesis of a compound of formula (IA) n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising reacting a compound of formula (IIA) n n n n n n n n n n with an oxidizing agent, thereby producing a compound of formula (IA). n The present invention is also directed to a method of preparing a compound or a tautomer thereof represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof. The method comprises the step of reacting a first starting compound represented by the following Structural Formula: n n n n n n n n n n in the presence of a mercuric salt, with a second starting compound represented by the following Structural Formula:

专利号:WO-2012002913-A1
优先权日:2010-07-02
标题:Process of forming a cyclic imide
发明人：HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
权利人:UNIV NANYANG TECH; HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
摘要:A process is provided for the synthesis of a cyclic imide. A primary amine and a diol compound are contacted in the presence of a Ruthenium (II) complex. The Ruthenium (II) catalyst includes at least one of an alicyclic ligand, an aromatic ligand, an arylalicyclic ligand, an arylaliphatic ligand and a phosphine ligand.

专利号:WO-9958688-A2
优先权日:1998-05-08
标题 :Nucleic acid molecules which code for enzymes derived from wheat and which are involved in the synthesis of starch

专利号:WO-9958690-A2
优先权日:1998-05-08
标题 :Nucleic acid molecules which code for enzymes derived from wheat and which are involved in the synthesis of starch

专利号:EP-1200615-B8
优先权日:1999-08-11
标题:Nucleic acid molecules derived from plants which code for enzymes which are involved in the synthesis of starch

专利号:WO-2009075890-A2
优先权日:2007-12-12
标题 :Method for synthesis of triazole compounds that modulate hsp90 activity