CAS: 556-24-1; Methyl Isovalerate

该化合物是化学配方C6H12O2的酯,其特点是水果味,通常与口味和香味相关,由异丙烯酸和甲醇通过酯化过程产生的反应形成.该化合物通常是室内温度无色液体,在水溶液中可溶于有机溶剂,但水溶液中可溶性有限.甲基异丙烯酸盐通常在食品工业中用作调味剂,在化妆品工业中用作香味.此外,它在各种化学中间体的生产中也有应用.其沸点和其他物理特性可能因环境条件而不同,但一般具有低毒性,适合消费品使用.然而,与许多酯一样,应当谨慎处理,以避免吸入或皮肤接触.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号924-50-5 3,3-二甲基丙烯酸甲酯 | CAS号201230-82-2 carbon monoxide | CAS号67-56-1 甲醇 | CAS号503-74-2 异戊酸 | CAS号108-24-7 乙酸酐 | CAS号108-10-1 甲基异丁基甲酮 | CAS号623-43-8 巴豆酸甲酯 | CAS号814-78-8 3-甲基-3-丁烯-2-酮 | CAS号60136-25-6 5-异丙基-2'-脱氧尿苷 | CAS号17432-95-0 5-isopropyluracil | CAS号541-46-8 异戊酰胺 | CAS号626-33-5 2-甲基-4-庚酮 | CAS号123-51-3 异戊醇 | CAS号14273-86-0 5-氯戊酸甲酯 | CAS号82504-50-5 chloromethyl is... | CAS号819-34-1 methyl 3-chloro...

合成工艺路线路线简述

    2-甲基-1-丁烯-3-酮置于platinum(Iv) Oxide,乙醚,溴体系中,化学反应生成 异戊酸甲酯
    参考文献:Wagner,Journal Of The American Chemical Society,1949,Vol. 71,P. 3216
    标题:Wagner,Journal Of The American Chemical Society,1949,Vol. 71,P. 3216

    海关参考信息

    专利信息


    专利号:US-2024217995-A1
    优先权日:2021-04-23
    标 题 :Compositions for chemical synthesis of peptides
    发明人:SEIFERT COLE
    权利人:SEDERMA SA
    摘要:The disclosure relates to compositions that can serve as anchors for the chemical synthesis of peptides. Anchor molecules can include GAP constituents, linker constituents, amino acid constituents, and/or stopper constituents. Anchor molecules can also include anchor peptides, wherein an anchor peptide can be removably coupled with an amino acid of a given sequence and act as a GAP anchor by achieving solubility control over the target peptide as it is synthesized via the addition of one or more other amino acids: the anchor peptide can then be removed from the target peptide. A novel method of peptide synthesis that utilizes novel anchor molecules and/or anchor peptides is also presented.

    专利号:US-9012625-B2
    优先权日:2009-04-07
    标 题 :Method for the synthesis of a trisaccharide
    发明人:DÉKANY GYULA; Ã?GOSTON KÃ?ROLY; BAJZA ISTVAN; BOUTET JULIEN; BØJSTRUP MARIE; FANEFJORD METTE; PÉREZ FIGUEROA IGNACIO; HEDEROS MARKUS; HORVATH FERENC; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; OLSSON JOHAN; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS
    权利人:DÉKANY GYULA; Ã?GOSTON KÃ?ROLY; BAJZA ISTVAN; BOUTET JULIEN; BØJSTRUP MARIE; FANEFJORD METTE; PÉREZ FIGUEROA IGNACIO; HEDEROS MARKUS; HORVATH FERENC; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; OLSSON JOHAN; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS; GLYCOM AS
    摘要:The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates.

    专利号:US-4250330-A
    优先权日:1977-04-13
    标题:Process for the recovery of the solvent and of the by-produced methylacetate in the synthesis of terephthalic acid
    发明人:COSTANTINI GIUSEPPE; PAOLI PIETRO; SERAFINI MAURO
    权利人:MONTEDISON SPA
    摘要:The invention refers to an improved process for the recovery of the solvent and of the by-produced methylacetate in the synthesis of terephthalic acid, said synthesis being usually consisting of an oxidation of paraxylene with air, in the presence of a catalyst system composed by cobalt, manganese and bromine, in a solvent consisting of acetic acid, according to the equation (1): n n C.sub.6 H.sub.4 (CH.sub.3).sub.2 +3 O.sub.2 →C.sub.6 H.sub.4 n n (COOH) 2 =2 H 2 O (1) n More particularly, the improved process of this invention comprises the oxidation of para-xylene in acetic acid solution and in the presence of a catalytic system based on manganese, bromine and cobalt, whereby water is formed and methylacetate is by-produced during the oxidation, whereby solid terephthalic acid is separated from the mother liquor and whereby one withdraws from the oxidation zone a liquid which is obtained by condensing the vapors released during the oxidation and which are mainly consisting of acetic acid and water, the improvement consisting of the fact that: n (a) the liquid obtained by condensing the released vapors and said mother liquor are fed both to an azeotropic distillation system in which the azeotropic agent is isobutyl-acetate; n (b) the light ends of the azeotropic distillation, richer in water, are condensed and demixed into two phases, wherein the aqueous phase, which is lower and contains isobutyl-acetate and methyl-acetate, is conveyed to a stripping, whereby isobutyl-acetate and methyl-acetate are recovered, and wherein the organic phase is recycled to the azeotropic distillation.

    专利号:US-RE37449-E
    优先权日:1987-02-06
    标题:Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
    发明人:KUTNEY JAMES P; CHOI LEWIS S L; NAKANO JUN; TSUKAMOTO HIROKI; BOULET CAMILLE A; MCHUGH MICHAEL
    权利人:UNIV BRITISH COLUMBIA
    摘要:The present invention relates to the synthesis of dimer alkaloid compounds, particularly those of the Catharantus (Vinca) family, from an indole unit, such as cantharanthine, and a dihydroindole unit, such as vindoline. A multi-step process is disclosed including the steps of (1) of 1,4-reduction of a first dimeric iminium intermediate to an enamine compound by reaction with a 1,4-dihydropyridine compound; (2) oxidative transformation of the resulting enamine to a second iminium intermediate under controlled aeration; (3) reduction of the second iminium intermediate to form the target dimer alkaloid compounds. The entire process can be conducted in a one-pot operation to obtain the target compounds without isolation of the intermediates.

    专利号:US-6177564-B1
    优先权日:1998-09-11
    标题:Process for the synthesis of N-benzyl-3-(4-fluorophenyl)-1-4-oxazin-2-one
    发明人:NELSON TODD D; BHUPATHY MAHADEVAN
    权利人:MERCK & CO INC
    摘要:The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of the formula:This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.

    专利号:US-9994508-B2
    优先权日:2012-12-11
    标 题:Versatile and functionalised intermediates for the synthesis of vitamin D and novel vitamin D derivatives
    发明人:LOPEZ PEREZ BORJA; SIGUEIRO PONTE RITA; MAESTRO SAAVEDRA MIGUEL A; MOURINO MOSQUERA ANTONIO
    权利人:ENDOTHERM GMBH
    摘要:Novel intermediates for the complete synthesis of vitamin D are provided that allow a great versatility of functional groups in the final vitamin derivatives. Vitamin derivatives that are epimeric in position 3 and vitamin derivatives with a wide range of functionalities in position 18, including compounds with isotopic labelling are provided.
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    合成参考文献


    摘要:Industrial Medicine and Surgery., 41(31), 1972
    摘要:Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(84), 1982
    摘要:Gigiena i Sanitariya. For English translation, see HYSAAV., 51(5)(61), 1986
    摘要:Bao, Z.; Wang, J., Science of Synthesis: Knowledge Updates, (2023) 2, 22.
    参考文献:10.1007/s10265-006-0019-2
    摘要:Azuma H, Kono M. Estragole (4-allylanisole) is the primary compound in volatiles emitted from the male and female cones of Cycas revoluta. J Plant Res. 2006 Nov;119(6):671–6. doi: 10.1007/s10265-006-0019-2.
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