CAS: 18677-48-0; 3,5-Dimethoxypyridine

相似化合物

109345-94-0 7295-76-3 88111-63-1

上下游产品

CAS号124-41-4 甲醇钠 | CAS号84476-99-3 2,5-二氟吡啶 | CAS号71902-33-5 3,5-二氟嘧啶 | CAS号2457-47-8 3,5-二氯吡啶 | CAS号865-33-8 甲醇钾 | CAS号625-92-3 3,5-二溴吡啶 | CAS号18344-57-5 3,5-dimethoxy-2... | CAS号204862-70-4 3,5-二甲氧基吡啶-4-甲醛

📜3,5-二氯吡啶置于sodium Methylate体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 2.0H,以59%的收率获得3,5-二甲氧基吡啶
参考文献:一些卤代吡啶与甲醇盐和甲硫醇盐离子在二甲基甲酰胺中的反应
标题:一些卤代吡啶与甲醇盐和甲硫醇盐离子在二甲基甲酰胺中的反应
摘要:2,6-和2,5-二溴吡啶和2,3-和3,5-二氯吡啶与异丙硫醇钠和甲硫醇钠的反应根据实验条件提供单取代或双取代的产物.相同的吡啶与甲醇钠反应,得到非常好收率的单取代产物.仅在2,6-二溴-和3,5-二氯吡啶中容易发生双取代.还描述了从卤代甲氧基吡啶或卤代硫代甲氧基吡啶开始的一些甲氧基硫代甲氧基吡啶的合成.双(烷硫基)吡啶可被hmpa中的钠裂解,得到双(巯基)吡啶.
Doi:10.1016/s0040-4020(01)96539-1

专利信息

专利号:US-8835466-B2
优先权日:2006-04-20
标 题 :Synthesis and uses of pyroglutamic acid derivatives
发明人：Ã?LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATÃ?A MARTÃ?N MA PAZ; SERNA PEREDA SONIA
权利人:Ã?LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATÃ?A MARTÃ?N MA PAZ; SERNA PEREDA SONIA; PRODIMED SA
摘要:Novel pyroglutamic acid derivatives (I), wherein R 1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R 2 , R 3 and R 4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumors, bacterial, fungal or viral infections, or autoimmune diseases.

专利号:US-2007249678-A1
优先权日:2006-04-20
标 题:Synthesis and uses of pyroglutamic acid derivatives

专利号:US-2009163555-A1
优先权日:2006-04-20
标 题:Synthesis and uses of pyroglutamic acid derivatives

专利号:US-7671206-B2
优先权日:2006-04-20
标题 :Synthesis and uses of pyroglutamic acid derivatives