CAS: 137076-54-1; 2-(4,7,10-Tris(2-(Tert-Butoxy)-2-Oxoethyl)-1,4,7,10-Tetraazacyclododecan-1-yl)Acetic Acid

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913542-71-9 122555-91-3 162148-48-3

上下游产品

CAS号192635-89-5 1,4,7,10-Tetraa... | CAS号825625-07-8 1,4,7,10-Tetraa... | CAS号79-08-3 溴乙酸 | CAS号122555-91-3 DO3A叔丁酯 | CAS号5292-43-3 溴乙酸叔丁酯 | CAS号1412494-55-3 tri-tert-butyl ... | CAS号294-90-6 轮环藤宁 | CAS号67-56-1 甲醇 | CAS号60239-18-1 轮环藤宁四乙酸 | CAS号75-65-0 叔丁醇 | CAS号865470-67-3 1,4,7,10-四氮杂环十二...

氯乙酸叔丁酯置于palladium 10% On Activated Carbon,氢气,碳酸氢钠,Potassium Carbonate体系中,用 甲醇,乙腈 用作溶剂,化学反应 46.0H,反应生成1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸三叔丁酯
参考文献:Development Of A Dual Functional Luminescent Sensor For Zinc Ion Based On A Peptidic Architecture
标题:Development Of A Dual Functional Luminescent Sensor For Zinc Ion Based On A Peptidic Architecture
摘要:A Synthetic Peptide Bearing A Lanthanide Complex,Tbotz Exhibits A Decrease Of Chromophore Fluorescence And A Concomitant Luminescence Enhancement Due To Sensitized Tb3+ Upon Zn2+ Binding. Thus,Tbotz Can Be A Valuable Tool For Ratiometric Sensing Of Zn2+ As Well As For Time-Resolved Fluorescence Detection With A Single Molecule. (C) 2012 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2012.10.061

专利信息

专利号:US-7851621-B2
优先权日:2005-06-30
标 题:Synthesis of deoxybiotinyl hexamethylenediamine-dota
发明人：MARZI MAURO; DI MARZO MARIA
权利人:SIGMA TAU IND FARMACEUTI
摘要:A process for the synthesis of deoxybiotinyl hexamethylenediamine0-DOTA is herein described. Said process comprises reacting biotinyl hexamithylenediamine with tri-t-butyl DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as a base.

专利号:WO-2025088147-A1
优先权日:2023-10-27
标题 :Theranostic psma-targeting ligands for the diagnosis and treatment of psma-expressing cancers and their solid phase synthesis
发明人：Schäfer Martin; BAUDER-WUEST ULRIKE; ROSCHER MAREIKE; REMDE YVONNE; BENEÅ OVÃ?-SCHÄFER MARTINA; BARINKA CYRIL; KUTILOVÃ? ZSÓFIA; MOTLOVÃ? LUCIA
权利人:DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS
摘要:The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and radiopharmaceuticals for the treatment of various disease states of PSMA-expressing cancers, especially prostate cancer, and metastases thereof. Further the present invention provides synthetic procedures for the synthesis of such PSMA-targeting ligands.

专利号:US-2024025866-A1
优先权日:2020-11-19
标 题:Synthesis of prostate specific membrane antigen (psma) ligands

专利号:CN-116438165-A
优先权日:2020-11-19
标 题:Synthesis of Prostate Specific Membrane Antigen (PSMA) ligands

专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人：SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

专利号:EP-1899354-B1
优先权日:2005-06-30
标题 :Synthesis of deoxybiotinyl hexamethylenediamine-dota