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1-chloromethoxy-3-methyl-butane i-Amyl alcohol benzyl chloride sodium isopentoxideDiphenylmethane isoamyl benzoate benzaldehyde isopentyl nitrite 📜以 四氢呋喃,甲苯 用作溶剂,化学反应 6.0H,以46 Mg的收率获得[(3-甲基丁氧基)甲基]苯
参考文献:通过钛环丁烷的质子分解进行位点特异性烯烃氢甲基化
标题:通过钛环丁烷的质子分解进行位点特异性烯烃氢甲基化
摘要:甲基在生物活性分子中普遍存在.因此,将这种烷基片段引入多官能结构的新策略引起了人们的极大兴趣.考虑到这一目标,报告了一种烯烃马尔可夫尼科夫氢甲基化的直接方法.该方法利用了cp 2 Ti(μ-Cl)(μ-Ch 2 )Alme 2 (Tebbe试剂)中的钛亚甲基与未活化的烯烃之间的简并复分解反应.所得环丁烷钛的原位质子解作用以化学,区域和位点选择性方式实现氢甲基化.该方法的广泛实用性在一系列含有侧醇,醚,酰胺,氨基甲酸酯和碱性胺的单取代和二取代烯烃中得到了证明.
Doi:10.1002/anie.202103278
海关参考信息
- 2902300000-甲苯
2905121000-正丙醇
2905130000-正丁醇
2906210000-苄醇 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
- 详情请参考:📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9809566-B2
优先权日:2012-09-06
标题:Organocatalytic process for asymmetric synthesis of decanolides
发明人:RAWAT VARUN; DEY SOUMEN; SHELKE ANIL MARUTI; SURYAVANSHI GURUNATH MALLAPPA; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention discloses organocatalytic process for asymmetric synthesis of highly enantioselective decanolide compounds in high yield with >99% ee. Further, the present invention disclose cost effective, improved organocatalytic process for asymmetric synthesis of highly enantioselective decanolides compounds from non-chiral, cheap, easily available raw materials.
专利号:US-10336784-B2
优先权日:2016-03-08
标 题 :Methods for modular synthesis of N-glycans and arrays thereof
发明人:WONG CHI-HUEY; WU CHUNG-YI; SHIVATARE SACHIN S
权利人:ACADEMIA SINICA
摘要:The present disclosure relates to novel modular methods for generating a diversity of N-glycans of high mannose, hybrid and complex types. The present disclosure also relates to exemplary arrays of the synthesized N-glycans spotted onto aluminium oxide coated slides. These arrays can be used to detect and analyze binding interactions between the synthesized N-glycans and glycan binding molecules, such as HIV-1 neutralizing antibodies. The present disclosure also relates to methods for identifying agents that bind to various types of molecules on the arrays and to defining the structural elements of the molecules on the arrays that bind to those agents. The arrays and methods provided herein may be used for general epitope identification, drug discovery and as analytical tools. The present disclosure also provides useful glycans and epitope determinants that are useful in detecting, diagnosing, recurrence monitoring and preventing pathological diseases such as HIV.
专利号:BR-112018073219-B1
优先权日:2016-07-21
标 题 :COMPOUND OF FORMULA I, PHARMACEUTICAL COMPOSITION, PROCESS FOR THE SYNTHESIS OF THESE COMPOUNDS AND USE OF THE SAME
专利号:CA-3109107-A1
优先权日:2018-08-13
标题 :Preparation of intermediate useful for synthesis of a diphenylmethane derivative for use as a sglt inhibitor
专利号:JP-H07508015-A
优先权日:1992-06-30
标题 :Synthesis of 1,4,7-triazacyclononane derivatives
专利号:RU-2017131026-A
优先权日:2015-03-13
标 题:METHOD OF SYNTHESIS OF NEW COMPOUNDS OBTAINED FROM 3-HYDROXYCLICENTO ACOXY ACID