CAS: 110549-07-0; (R)-1,2-Epoxyheptane

上下游产品

n-butyl magnesium bromide (R)-(-)-epichlorohydrin (2R)-heptane-1,2-diol (R)-1-chloro-2-heptanol (3S,5R)-3-(4'-Heptyl-biphenyl-4-yl)-5-pentyl-dihydro-furan-2-one (3R,5R)-3-(4'-Heptyl-biphenyl-4-yl)-5-pentyl-dihydro-furan-2-one (R)-1-Phenylsulfanyl-heptan-2-ol (R)-3-[2-(4'-Heptyl-biphenyl-4-yl)-ethyl]-5-pentyl-dihydro-furan-2-one

1-庚烯置于(1R,2R)-(-)-N,N'-Bis(3,5-Di-Tert-Butylsalicydene)-1,2-Cyclohexanediaminocobalt(II),溶剂黄146,间氯过氧苯甲酸体系中,用 二氯甲烷,水 用作溶剂,化学反应 35.0H,反应生成(R)-(+)-1,2-环氧庚烷
参考文献:从半绿藻毒素,半绿藻酸和二聚萘并吡喃酮的全合成及其在伯基特 B 细胞淋巴瘤中的生物活性
标题:从半绿藻毒素,半绿藻酸和二聚萘并吡喃酮的全合成及其在伯基特 B 细胞淋巴瘤中的生物活性
摘要:合成了各种萘并吡喃酮并测试了它们的细胞毒性和细胞凋亡活性.该合成使用两种结构单元进行,这两种结构单元由对映体纯的环氧乙烷和乙酰乙酸甲酯制备,然后彼此反应形成萘并吡喃酮.合成了单体和二聚萘并吡喃酮,然后进行了构效关系研究.
Doi:10.1002/chem.202400559

专利信息

专利号:US-4707554-A
优先权日:1984-12-07
标 题 :Method of obtaining derivatives of 4β-/1'-alken-1'-yl/-2ξ,5α-dαβ-4,5,6,6α.beta.
发明人：ACHMATOWICZ BARBARA; DANIEWSKI ANDRZEJ R; MARCZAK STANISLAW; PANKOWSKI JACEK; WICHA JERZY
权利人:POLSKA AKADEMIA NAUK INSTYTUT
摘要:A new method has been disclosed for obtaining derivatives of 4β-/1'-alken-1'-yl/-2ξ,5â•?-dihydroxy-3,3aβ,4,5,6,6aβ-hexahydro-2H-cyclopenta [b] furane useful in the synthesis of prostaglandins or their analogs, and a method for obtaining new sulphonyl initial compounds of the general formula 4, in which Z denotes a hydrogen atom or a protective group, Y denotes a group of the formula â•?CHOZ 1 , in which Z 1 has the meaning stated for Z, whereby protective groups Z and Z 1 may be the same or different, and Ar denotes optionally a substituted aryl group. n In the method according to the invention the new sulphonyl derivative of the general formula 4 is alkylated with an electrophilic agent comprising: carbonyl derivatives, oxiranes and halohydrins or their derivatives; the alkylation product is transformed into derivatives of 4β-/1'-alken-1'-yl/-2ξ,5α-dihydroxy-3,3aβ,4,5,6,6a.beta.-hexahydro-2H-cyclopenta[b] furane in reactions which ensure obtaining a double bond C 13 -C 14 . n New sulphonyl initial compounds of the general formula 4 are obtained from lactone of the general formula 11, in which Z has the above stated meaning and L° denotes a leaving group, which is transformed into a sulphide; the obtained lactone-sulphide is reduced to lactol, and thereafter lactol-sulphide is oxidized to te sulphonyl derivative.

专利号:US-6177087-B1
优先权日:1994-06-24
标 题:Non-antigenic amine derived polymers and polymer conjugates
发明人：GREENWALD RICHARD B; MARTINEZ ANTHONY; PENDRI ANNAPURNA
权利人:ENZON INC
摘要:Substantially non-antigenic polymers containing pI and/or pH optimum modulating moieties are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed.

专利号:US-8946466-B2
优先权日:2010-05-18
标 题 :Method for producing polyether carbonate polyols
发明人：Gürtler Christoph; Hofmann Jörg; WOLF AUREL; GRASSER STEFAN
权利人:Gürtler Christoph; Hofmann Jörg; WOLF AUREL; GRASSER STEFAN; BAYER IP GMBH
摘要:The present invention relates to a process for the preparation of polyether carbonate polyols from one or more H-functional starter substances, one or more alkylene oxides and carbon dioxide in the presence of at least one double metal cyanide catalyst, wherein the cyanide-free metal salt, the metal cyanide salt or both the mentioned salts used for the preparation of the double metal cyanide catalyst contain(s) from 0.3 to 1.8 mol base equivalents (based on 1 mol of the metal cyanide salt used for the synthesis of the catalyst) of alkaline metal hydroxide, metal carbonate and/or metal oxide.

专利号:WO-2024153757-A1
优先权日:2023-01-19
标 题 :Controlled addition of ligand in polyol synthesis
发明人：BLANCO GONZÃ?LEZ María Dolores; DUEÑAS DÃ?EZ MARTA; FRAGA TRILLO LUISA MARÃ?A; GARCÃ?A RUIZ MÓNICA; CARAZO ANGULO JOSÉ ANTONIO; MIRANDA LÓPEZ-MARÃ?N JUAN DE DIOS
权利人:REPSOL SA
摘要:The present invention relates to a process for the alkali metal base-catalyzed preparation of polyols comprising oxyalkylene units, comprising the addition of a ligand for chelating said alkali metal over a total period of time t ≥ 5 min during the reaction time, to a polyol comprising oxyalkylene units, and to the use of said polyol.

专利号:EP-0468840-A2
优先权日:1990-07-06
标 题:Process for the selective epoxidation of unsaturated (meth)acrylates, new functional (meth)acrylates so obtained and their use in the synthesis of new polymers

专利号:CN-113333019-A
优先权日:2021-04-29
标题:A kind of method for catalyzing synthesis of organophosphorus flame retardant by Lewis acid ionic liquid