CAS: 67527-71-3; 4-Amino-1-[4-[[(2S)-2-Amino-3-Hydroxy-1-Oxopropyl]Amino]-9-[(Aminoiminomethyl)Amino]-6-C-Carboxy-2,3,4,7,9-Pentadeoxy-α-L-Talo-Non-2-Enopyranosyl]-5-(Hydroxymethyl)-2(1H)-Pyrimidinone
该化合物是一种化学化合物,被归类为抗生素,主要以其在农业应用中,特别是在植物保护中使用为名;通过细菌菌株发酵产生; 灭蚁灵针对各种真菌病原体开展了广泛的活动,使其在植物病虫害的管理中具有宝贵价值; 抑制目标生物体中特定生物化学途径从而干扰其生长和生殖的复合功能; 灭蚁灵的特点是其对非目标生物体的毒性相对较低,这增强了其作为生物杀虫剂的吸引力; 此外,人们还知道,在各种环境条件下,这种物质具有稳定性,有助于其在实地应用中的有效性; 化合物的动作方式及其对抗抗性病原体菌株的功效是不断研究的领域,因为科学家们力求在可持续农业中优化其使用; 总的来说,灭蚁灵素是发展环境友好型农业做法方面的一大进步.
- 英文名称4-Amino-1-[4-[[(2S)-2-Amino-3-Hydroxy-1-Oxopropyl]Amino]-9-[(Aminoiminomethyl)Amino]-6-C-Carboxy-2,3,4,7,9-Pentadeoxy-α-L-Talo-Non-2-Enopyranosyl]-5-(Hydroxymethyl)-2(1H)-Pyrimidinone
- 中文名称米多霉素
- IUPAC名称2-(3-(2-amino-3-hydroxypropanamido)-6-(4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1(2H)-yl)-3,6-dihydro-2H-pyran-2-yl)-5-guanidino-2,4-dihydroxypentanoic acid
- 其它别名Mildiomycin; 4-Amino-1-[4-[[(S)-2-Amino-3-Hydroxy-1-Oxopropyl]Amino]-9-Guanidino-6-Carboxy-2,3,4,7,9-Pentadeoxy-α-L-Talo-Non-2-Enopyranosyl]-5-(Hydroxymethyl)Pyrimidin-2(1H)-One; 4-Amino-1-[4-[[(S)-2-Amino-3-Hydroxy-1-Oxopropyl]Amino]-9-Guanidino-6-Carboxy-2,3,4,7,9-Pentadeoxy-α-L-Talo-Nona-2-Enopyranosyl]-5-(Hydroxymethyl)Pyrimidin-2(1H)-One; 2(1H)-Pyrimidinone, 4-Amino-1-[4-[[(2S)-2-Amino-3-Hydroxy-1-Oxopropyl]Amino]-9-[(Aminoiminomethyl)Amino]-6-C-Carboxy-2,3,4,7,9-Pentadeoxy-α-L-Talo-Non-2-Enopyranosyl]-5-(Hydroxymethyl)-; Midomycin
- CAS编号67527-71-3
- MFCD编号:MFCD01939748
- FDA UNII编号:WPS3TSW377
- 分子式:C19H30N8O9分子量:514.5
- 产品CID: 1658236
- 产品分类有机原料 → 有机酸及其衍生物 → 羧酸及其衍生物
物理性质
- 熔点>300° (monohydrate)
- 密度1.81±0.1 g/cm3(预测)
- PH:D20 +100° (c = 0.5 in water); +78.5° (c = 0.5 in 0.1N HCl)
- pKa:2.8, 4.3, 7.2, >12(at 25°C)
- LogP:-8.1
- 外观形态固体-粉末
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用米多霉素(67527-71-3)的用途:主要可用于防治各种作用的白粉病.其对Myclbacterinm phlei和Rhodo-torularubra有较强的活性,但对革兰氏阳性和阴性细菌,酵母,腐生真菌和肤藓菌几乎无活性.对寄生真菌单丝壳属,白粉菌属叉丝单囊壳属,叉丝壳,钩丝壳属和双壁壳属有优良防效.对内丝白粉菌属和球针壳属也有效.
- 性质描述米多霉素(67527-71-3)的性状:1.其为吸湿性白色粉末,熔点＞300°C(分解).2.易溶于水,微溶于吡啶,二甲基亚砜,N,N-二甲基乙酰胺,二恶烷,四氢呋喃.3.在中性介质中稳定,在pH9的碱性水溶液中和pH2的酸性水溶液中不稳定.毒性:对哺乳动物的急性毒性:在浓度为1g/L时对兔眼晴和皮肤无刺激.对鱼毒性:鲤鱼LC50(72小时)＞40mg/L,水蚤LC50(6小时)＞20mg/L.
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
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专利信息
专利号:US-9968097-B2
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
发明人：WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
专利号:US-9706777-B2
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of amino acid or protein biosynthesis, inhibitors of ATP production and inhibitors of the cell wall synthesis
发明人：WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
专利号:US-2015272130-A1
优先权日:2012-12-03
标 题:Composition comprising a biological control agent and a fungicide
发明人：WACHENDORFF-NEUMANN ULRIKE; DAHMEN PETER; SAWADA HARUKO
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent selected from the group consisting of Paecilomyces lilacinus strain 251 (AGAL No. 89/030550) and Coniothyrium minitans CON/M/91-08 (DSM 9660) and/or a mutant of these strains having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against nematodes, insects and/or phytopathogens, and at least one fungicide (I) selected from the group consisting of compounds capable to introduce a host defence, inhibitors of the amino acid and/or protein biosynthesis, inhibitors of the ATP production, inhibitors of the cell wall synthesis, inhibitors of the lipid and membrane synthesis, inhibitors of the melanine biosynthesis, inhibitors of the nucleic acid synthesis, inhibitors of the signal transduction, compounds capable to act as an uncoupler, and other fungicides in a synergistically effective amount. Furthermore, the present invention relates to a kit of parts comprising said composition and the use of said composition.
专利号:US-2015105251-A1
优先权日:2012-05-30
标 题 :Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
专利号:CN-104507319-A
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from an inhibitor of lipid membrane synthesis, an inhibitor of melanin biosynthesis, an inhibitor of nucleic acid synthesis or an inhibitor of signal transduction
专利号:CN-104507319-B
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from an inhibitor of lipid membrane synthesis, an inhibitor of melanin biosynthesis, an inhibitor of nucleic acid synthesis or an inhibitor of signal transduction
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1. Feduchi E, Cosín M, Carrasco L. Mildiomycin: a nucleoside antibiotic that inhibits protein synthesis. J Antibiot (Tokyo). 1985 Mar;38(3):415-9. doi: 10.7164/antibiotics.38.415. 31(6):519-24. doi: 10.7164/antibiotics.31.519.合成参考文献
摘要:Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan., 19(S135), 1994
摘要:Journal of Antibiotics., 31(519), 1978 []
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