CAS: 580-16-5; 6-Hydroxyquinoline

相似化合物

580-18-7 580-20-1 5263-87-6

上下游产品

CAS号100-02-7 对硝基苯酚 | CAS号56-81-5 甘油 | CAS号98-95-3 硝基苯 | CAS号612-57-7 6-氯喹啉 | CAS号123-30-8 对氨基苯酚 | CAS号5263-87-6 6-甲氧基喹啉 | CAS号144-55-8 碳酸氢钠 | CAS号108825-21-4 6-(benzyloxy)qu... | CAS号51-66-1 4'-甲氧基乙酰苯胺 | CAS号87707-14-0 1a,7b-Dihydroox... | CAS号100926-75-8 quinolin-6-yl N... | CAS号103796-41-4 1,2,3,4-四氢喹啉-6-胺 | CAS号406463-06-7 6-喹啉硼酸频哪醇酯 | CAS号3373-00-0 6-羟基-1,2,3,4-四氢喹啉 | CAS号396-30-5 6-氟喹啉 | CAS号580-15-4 6-氨基喹啉 | CAS号152365-47-4 3,3-diphenylpyr... | CAS号21979-59-9 Quinolinium,6-m... | CAS号5263-87-6 6-甲氧基喹啉 | CAS号24306-33-0 喹啉-6-基乙酸酯

非那西丁置于硫酸,氢溴酸,砷酸,原砷酸体系中,化学反应生成 6-羟基喹啉
参考文献:Fujita Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1954,Vol. 74,P. 206
标题:Fujita Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1954,Vol. 74,P. 206

专利信息

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:US-6417380-B1
优先权日:1987-12-31
标 题 :Synthesis of 1,2-dioxetanes and intermediates therefor
发明人：BRONSTEIN IRENA Y; EDWARDS BROOKS
摘要:Compounds having the formula: n wherein T is a polycycloalkylidene group (e.g., adamant-2-ylidene); R is a C 1-20 alkyl, aralkyl or cycloalkyl group; and Y is a fluorescent chromophore (e.g., n m-phenylene), produced by reacting a compound having the formula: n with an R-ylating agent (e.g., R 2 SO 4 ) in the presence of an alkali metal alkoxide in a polar aprotic solvent. Also, compounds having the formula: n are produced by reacting a compound having the formula: n with n wherein X is an electronegative leaving group (e.g., a halogen anion such as chloride ion) in the presence of a Lewis base (e.g., a trialkyl-amine) dissolved in an aprotic organic solvent (e.g., benzene or toluene). Also, compounds having the formula n are produced by reacting a compound of the formula n with a tetra-O-acylated-O-hexopyranoside halide, then hydrolyzing off the protective acyl groups. The aforementioned compounds and procedures are useful in the synthesis of enzyme-cleavable 1,2-dioxetane ring systems that can serve as members of a binding pair employed, for example, in chemiluminescent immunoassays, DNA probe assays, and direct assays for an enzyme.

专利号:US-5777133-A
优先权日:1987-12-31
标 题:Synthesis of 1, 2-dioxetanes and intermediates therefor
发明人：BRONSTEIN IRENA Y; EDWARDS BROOKS
权利人:TROPIX INC
摘要:Compounds having the formula: ##STR1## wherein T is a polycycloalkylidene group (e.g., adamant-2-ylidene); R is a C 1-20 alkyl, aralkyl or cycloalkyl group; and Y is a fluorescent chromophore (eg., m-phenylene), produced by reacting a compound having the formula: ##STR2## with an R-ylating agent (e.g., R 2 SO 4 ) in the presence of an alkali metal alkoxide in a polar aprotic solvent. Also, compounds having the formula: ##STR3## are produced by reacting a compound having the formula: ##STR4## wherein X is an electronegative leaving group (e.g., a halogen anion such as chloride ion) in the presence of a Lewis base (e.g., a trialkyl-amine) dissolved in an aprotic organic solvent (e.g., benzene or toluene). Also, compounds having the formula ##STR5## are produced by reacting a compound of the formula ##STR6## with a tetra-O-acylated-O-hexopyranoside halide, then hydrolyzing off the protective acyl groups. The aforementioned compounds and procedures are useful in the synthesis of enzyme-cleavable 1,2-dioxetane ring systems that can serve as members of a binding pair employed, for example, in chemiluminescent immunoassays, DNA probe assays, and direct assays for an enzyme.

专利号:US-4956477-A
优先权日:1987-12-31
标 题:Synthesis of 1,2-dioxetanes
发明人：BRONSTEIN IRENA Y; EDWARDS BROOKS
权利人:TROPIX INC
摘要:Compounds having the formula: ##STR1## wherein T is a polycycloalkylidene group (e.g., adamant-2-ylidene); R is a C 1-20 alkyl, aralkyl or cycloalkyl group; and Y is a fluorescent chromophore (e.g., m-phenylene), produced by reacting a compound having the formula: ##STR2## with an R-ylating agent (e.g., R 2 SO 4 ) in the presence of an alkali metal alkoxide in a polar aprotic solvent. Also, compounds having the formula: ##STR3## are produced by reacting a compound having the formula: ##STR4## wherein X is an electronegative leaving group (e.g., a halogen anion such as chloride ion) in the presence of a Lewis base (e.g., a trialkyl-amine) dissolved in an aprotic organic solvent (e.g., benzene or toluene). Also, compounds having the formula ##STR5## are produced by reacting a compound of the formula ##STR6## with a tetra-O-acylated-O-hexopyranoside halide, then hydrolyzing off the protective acyl groups. The aforementioned compounds and procedures are useful in the synthesis of enzyme-cleavable 1,2-dioxetane ring systems that can serve as members of a binding pair employed, for example, in chemiluminescent immunoassays, DNA probe assays, and direct assays for an enzyme.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-10927135-B2
优先权日:2017-08-03
标 题:Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates
发明人：KANG JUN YONG; HUANG HAI
权利人:THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIV OF NEVADA LAS VE
摘要:Provided herein are phosphates, thiophosphates, phosphonates, and phosphinates, methods of making same, and methods of using these compounds and methods for the generation of pharmaceutically relevant phosphate, phosphonate, and phosphinate analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.