CAS: 36489-03-9; 2-(Ethylthio)Ethan-1-Amine

该化合物是一种含硫的矿物质化合物,其特点是乙基硫化合物和主要矿物质功能组,这种结构在有机合成中赋予了反活动作用,特别是作为制药,农用化学品和特殊化学物质的一个构件.乙基磷组增强了亲脂性,有可能改善药物设计中的生物利用率,而主要矿物质则允许通过凝结或对流反应进一步衍生.它的平衡极性能够使有机和水媒介的溶解性,便利了多种反应条件.该化合物在标准处理条件下的稳定使得它成为研究和工业应用的实用中间体.建议在惰性大气中适当地储存,以防止硫酸的氧化.

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CAS号75-03-6 碘乙烷 | CAS号60-23-1 β-巯基乙胺 | CAS号151-56-4 氮丙啶 | CAS号75-08-1 乙硫醇 | CAS号926-39-6 2-氨基乙醇硫酸氢酯 | CAS号83586-83-8 Azirino[2,3:3,4... | CAS号89500-01-6 2-ethylsulfanyl...

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成2-(乙硫基)乙胺
    参考文献:Schneider,Justus Liebigs Annalen Der Chemie,1912,Vol. 386,P. 340
    标题:Schneider,Justus Liebigs Annalen Der Chemie,1912,Vol. 386,P. 340

    海关参考信息

    专利信息


    专利号:US-2006122240-A1
    优先权日:2002-11-05
    标题 :Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof
    发明人:SEMPLE GRAEME; SKINNER PHILIP J; CHERRIER MARTIN C; WEBB PETER; TAMURA SUSAN Y
    权利人:ARENA PHARM INC
    摘要:The present invention relates to certain benzotriazole carboxylic acid or ester derivatives of Formula (I), pharmaceutically acceptable salts and solvates thereof, which exhibit useful pharmaceutical properties, for example, as agonists for the GPCR referred to as hRUP38. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the prophylaxis or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of -glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers and the like.

    专利号:WO-0010565-A1
    优先权日:1998-08-18
    标 题 :Growth hormone secretagogues
    发明人:DODGE JEFFREY ALAN; HAUSER KENNETH LEE; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR CHARLES WILLIS III; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROBERT LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
    权利人:LILLY CO ELI; DODGE JEFFREY ALAN; HAUSER KENNETH LEE; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR CHARLES WILLIS III; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROBERT LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
    摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

    专利号:US-5064962-A
    优先权日:1989-02-23
    标题:Diaminothiophenes
    发明人:WIESENFELDT MATTHIAS; ETZBACH KARL-HEINZ
    权利人:BASF AG
    摘要:Diaminothiophenes of the formula or tautomers thereof, where R1 and R2 are each hydrogen or together are where T1 is hydrogen, alkyl or phenyl, T2 and T3 are, independently of one another, alkyl or phenyl, or T2 and T3 together with the nitrogen linking them are a heterocyclic radical, R3 is substituted amino and R4 is alkanoyl, benzoyl, cyano, nitro or where T4 is hydrogen, alkyl or phenyl and T5 is the radical of a primary amine or of an active methylene compound, are prepared as described. The present diaminothiophene compound is useful in the synthesis of dyes, crop protection agents and pharmaceuticals.

    专利号:US-6992097-B2
    优先权日:1998-08-18
    标 题 :Growth hormone secretagogues
    发明人:HAUSER KENNETH LEE; DODGE JEFFREY ALAN; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR III CHARLES WILLIS; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROGER LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
    权利人:LILLY CO ELI
    摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s10913-008-0018-x
    摘要:Chanturia VA, Nedosekina TV, Stepanova VV. Experimental-analytical methods of the investigating the effect of complexing reagents on platinum flotation. Journal of Mining Science. 2008 May;44(3):283–8. doi: 10.1007/s10913-008-0018-x.
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