CAS: 28874-51-3; Sodium (S)-5-Oxopyrrolidine-2-Carboxylate

专利信息

专利号:US-9522192-B2
优先权日:2012-12-13
标 题:Polyethylene glycol derivatives of palmitoylethanolamide and analogous acylethanolamides
发明人：CALIGNANO ANTONIO; D'AGOSTINO GIUSEPPE; LANERI SONIA; MELI ROSARIA; OSTACOLO CARMINE; RUSSO ROBERTO; SACCHI ANTONIA; TRONINO DIANA; DELLA VALLE FRANCESCO; DELLA VALLE MARIA FEDERICA; MARCOLONGO GABRIELE
权利人:EPITECH GROUP SRL
摘要:The synthesis of a series of Polyethylene glycol conjugates (esters and carbonates) of PEA and its analogous acylethanolamides, have higher water solubility and good hydrophilic/lipophilic balance, resulting in (i) improved accumulation in tissues (particularly skin and mucosae), (ii) prolonged release, and (iii) increased bioavailability. Improvement of PEA and analogous acylethanolamides levels in the tissues—particularly in the skin and mucosae—and their prolonged release is due to the improved bioavailability of related conjugates. Conjugates are able to extend the time frame in which PEA and analogous acylethanolamides exert their pharmacological effects.

专利号:WO-2006097348-A1
优先权日:2005-03-15
标 题:Use of agents such as nonpolymeric nitric oxide donors for making the lips full again and/or colouring the lips
发明人：CALS-GRIERSON MARIE-MADELEINE
权利人:OREAL; CALS-GRIERSON MARIE-MADELEINE
摘要:The invention relates in particular to the cosmetic use (i) of at least one agent for promoting the production of NO in and/or on the lips, chosen from nitric oxide NO donors or precursors; nonpolymeric NO releasers; and NO synthase synthesis and/or activity stimulators; or (ii) of other agents for promoting microcirculation in the skin, chosen from potassium channel openers; calcium channel blockers; phosphodiesterase inhibitors; flavonoids; vasodilator peptides that are not NO donors; temperature modulators; agents for promoting the stimulation and/or maintenance of angiogenesis; agents for promoting the stimulation of endothelial cell proliferation; agents for promoting endothelial cell migration; and mixtures thereof, in a makeup and/or care composition for the lips, as an agent for naturally making the lips full again and/or naturally coloring the lips. It also relates to specific care and/or makeup compositions for the lips containing said agent, and also to a cosmetic process aimed at making the lips naturally full and/or colored, using said compositions .

专利号:EP-2153815-A1
优先权日:2008-08-05
标题 :Use of urea containing compositions
发明人：TRULLAS CABANAS CARLOS RAMON; KRUTMANN JEAN PROF DR
权利人:ISDIN SA
摘要:The present invention relates to the use of a composition comprising urea for increasing the expression of at least one gene associated with the collagen synthesis within the dermis of the skin. nThe urea composition has been used for preventing/treating damages of the skin such as signs of aging, wrinkles, damages associated with UV-radiation, wounds, skin diseases.

专利号:US-2025051274-A1
优先权日:2023-08-07
标 题 :Method for preparing 2-hydroxy-5-oxoproline
发明人：MARTINEZ RODOLFO; MARTINEZ NATHAN; BLASKOVIC ROBERT; GLASS DAVID REMBERT; UNKEFER CLIFFORD J
权利人:MILLENNIUM ENTPR INC
摘要:The compound 2-hydroxy-5-oxoproline salt can be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation and nitrogen fixation and photosynthetically derived chemical energy when applied to plants through their roots and/or through their foliar portions. The embodiments provide an improved chemical synthesis for this compound which is performed in a single step reaction using ozone with 2-pyrrolidone-5-carboxylic acid. The steps of dissolving Sodium 2-pyrrolidone-5-carboxylate in aqueous solution and reacting a molar excess of ozone with the aqueous solution of sodium 2-pyrrolidone-5-carboxylate at a temperature between 20° C. and 100° C. can be carried out such that sodium 2-hydroxy-5-oxoproline salt is formed.

专利号:US-11759412-B2
优先权日:2016-12-21
标题 :Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids
发明人：GUELAKIS MARIAN PEREIRA; LEE JIANMING; ROSA JOSE GUILLERMO; MADISON STEPHEN ALAN; MI TINGYAN; DAMODARAN ANITA; KUMARI ANNU; HUANG NAN; HARICHIAN BIJAN
权利人:CONOPCO INC
摘要:Topical personal care compositions containing amino acids and 4-substituted resorcinols for potentiating glutathione synthesis within skin cells. The compositions can be used to improve skin appearance of chronological aging or photoaging, resulting from exposure to UV light/sunlight, or environmental pollutants. The compositions are also useful for attaining even skin color and reducing pigmentation, age spots and discoloration.

专利号:EP-4506338-A1
优先权日:2023-08-07
标题:Method for preparing 2-hydroxy-5-oxoproline
发明人：MARTINEZ RODOLFO; MARTINEZ NATHAN; BLASKOVIC ROBERT; GLASS DAVID REMBERT; UNKEFER CLIFFORD J
权利人:MILLENNIUM ENTPR INC
摘要:The compound 2-hydroxy-5-oxoproline salt can be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation and nitrogen fixation and photosynthetically derived chemical energy when applied to plants through their roots and/or through their foliar portions. The embodiments provide an improved chemical synthesis for this compound which is performed in a single step reaction using an oxidizing agent (such as ozone) with a salt of 2-pyrrolidone-5-carboxylic acid.