CAS: 1682-20-8; 2,3,5,6-Tetrafluoropyridin-4-Amine

相似化合物

105252-95-7 1227602-34-7 189281-61-6

上下游产品

CAS号700-16-3 五氟吡啶 | CAS号1735-44-0 2,3,5,6-四氟-4-肼基吡啶 | CAS号7664-41-7 氨 | CAS号86249-71-0 TETRAFLUORO-4-(... | CAS号333720-11-9 N-(2,3,5,6-Tetr... | CAS号3511-89-5 2,3,5,6-tetrafl... | CAS号105608-95-5 N-(2,3,5,6-tetr... | CAS号39066-42-7 4-azido-2,3,5,6... | CAS号105252-94-6 2(1H)-Pyridinon... | CAS号105252-96-8 4-氨基-3,5-二氟-2(1... | CAS号3511-90-8 4-溴-2,3,5,6-四氟吡啶 | CAS号81-62-9 1-氨基-4-溴蒽醌 | CAS号105252-95-7 2,3,5-三氟吡啶-4-胺 | CAS号2872-47-1 9,10-Anthracene... | CAS号86249-71-0 TETRAFLUORO-4-(... | CAS号63489-55-4 4-氨基-2,3,6-三氟吡啶 | CAS号39066-42-7 4-azido-2,3,5,6...

📜2,3,5,6-四氟-4-肼基吡啶置于氢碘酸体系中,用 水 用作溶剂,以54%的收率获得4-氨基-2,3,5,6-四氟吡啶
参考文献:Chambers,R. D.; Hutchinson,J.; Musgrave,W. K. R.,Journal Of The Chemical Society
标题:Chambers,R. D.; Hutchinson,J.; Musgrave,W. K. R.,Journal Of The Chemical Society

专利信息

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

专利号:WO-9948868-A9
优先权日:1998-03-26
标 题 :Heterocyclic classes of compounds for the modulating tyrosine protein kinase
发明人：FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
权利人:SUGEN INC; UNIV NEW YORK; MAX PLANCK INST FUR BIOCHEMIE; FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
摘要:The invention relates to certain indolinone-based and pyrazolylamide-based compounds, their method of synthesis, and combinatorial libraries consisting of the compounds. The invention also relates to methods of modulating the function of protein kinases using these compounds and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.