CAS: 133057-83-7; 4-Benzyloxy-3-Fluorophenylboronic Acid

相似化合物

156635-88-0 156635-87-9 957034-74-1

上下游产品

4-bromo-2-fluorophenol benzyl bromide 1-benzyloxy-4-bromo-2-fluorobenzene Trimethyl borate 4-benzyloxy-3-fluoro-4'-(trans-4-pentylcyclohexyl)biphenyl 6-{N-[4-(benzyloxy)-3-fluorophenyl]methanesulfonamido}-2-(4-chlorophenyl)-5-cyclopropyl-N-methyl-1-benzofuran-3-carboxamide ethyl 4-(benzyloxy)-3-fluorobenzoate methyl 4'-(benzyloxy)-3,3'-difluoro-[1,1'-biphenyl]-4-carboxylate

4-苄氧基-3-氟溴苯置于正丁基锂,硼酸三异丙酯,盐酸,水体系中,用 四氢呋喃,正己烷,水 用作溶剂,化学反应 2.0H,以88%的收率获得4-苄氧基-3-氟苯硼酸
参考文献:Cycloalkylamine Derivative
标题:Cycloalkylamine Derivative

专利信息

专利号:US-9308194-B2
优先权日:2013-11-28
标 题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：LINGARD IAIN; HAMPRECHT DIETER
权利人:BOEHRINGER INGELHEIM INT
摘要:A compound of formula I, n nwherein the groups R 1 , R 2 , R 3 , X, m, and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.