CAS: 114-63-6; Sodium 4-Hydroxybenzoate

该化合物是p-氢氧苯乙酸钠盐,由于其抗微生物性能,在食品和化妆品中通常用作防腐剂,它看起来像白色的脱白晶粉,在水中可溶解,适合各种水溶制剂.该化合物以其抑制细菌,酵母和霉菌生长的能力而著称,有助于延长产品的储存寿命.在建议浓度内使用时,一般都认为钠-氢氧苯甲酸盐是安全的,尽管某些人可能会经历过敏反应.其稳定性受pH影响,通常在微酸性到中性条件下观测到最佳效果.此外,它经常与其他防腐蚀剂结合使用,以提高总体功效.作为化学物质,必须谨慎处理,遵循安全准则以避免潜在刺激或不利影响.

结构式图片

相似化合物

7720-19-6 99-96-7 54-21-7

物理性质

MSDS等安全信息

欧盟法规

欧盟化妆品法规附录五-准用防腐剂清单ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号124-38-9 二氧化碳 | CAS号139-02-6 苯酚钠 | CAS号532-32-1 苯甲酸钠 | CAS号94-18-8 4-羟基苯甲酸苯甲酯 | CAS号56442-22-9 间(苯基甲氧基)苯甲酸苯基甲基酯

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    专利信息


    专利号:US-2005182036-A1
    优先权日:2002-08-02
    标题:Medicinal composition containing an HMG-CoA reductase inhibitor
    发明人：KONDO TATSUHITO; TAKAGI IKUO; NAKAYAMA MASATO; TORIZUMI YASUHIRO
    权利人:SANKYO CO
    摘要:A pharmaceutical composition for promoting the synthesis of vascular endothelial nitrogen oxide and/or maintaining or elevating the concentration of vascular endothelial nitrogen oxide in the blood, or a pharmaceutical composition for improving blood lipids. The pharmaceutical composition contains an HMG-CoA reductase inhibitor; and gamma-oryzanol, and/or thiamines. For treatment, the components of the composition can be administered together, as a composition, or separately.

    专利号:WO-2023023572-A1
    优先权日:2021-08-19
    标题:Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto
    发明人：BAUM ERICH; CROUSE GARY; DEMETER DAVID; GIAMPIETRO NATALIE; Horty Lindsey; PETKUS JEFFREY; SPARKS THOMAS
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Provided are compounds having the structure of Formula One or Formula Two: Formula One, or Formula Two. Pesticidal compositions and their uses are disclosed. Also disclosed are methods of synthesis for compounds disclosed herein.

    专利号:CN-104479600-A
    优先权日:2015-01-07
    标 题 :Synthesis method of sodium methyl silicate catalyzed rock wool production sizing adhesive

    专利号:CN-116621823-A
    优先权日:2023-07-06
    标 题:Diagnosis of metastatic lymph node near-infrared fluorescent tracer, synthesis method and application

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    主要参考文献

    [参考文献]: C N Banti, Et Al. Mixed Ligand-Silver(I) Complexes With Anti-Inflammatory Agents Which Can Bind To Lipoxygenase And Calf-Thymus Dna, Modulating Their Function And Inducing Apoptosis. Metallomics. 2012 Jun;4(6):545-60.
    [参考文献]: Carole Seidel, Et Al. Antiproliferative And Proapoptotic Activities Of 4-Hydroxybenzoic Acid-Based Inhibitors Of Histone Deacetylases. Cancer Lett. 2014 Feb 1;343(1):134-46.
    [参考文献]: Danni Huang, Et Al. Development Of Magnetic Multiwalled Carbon Nanotubes As Solid-Phase Extraction Technique For The Determination Of P-Hydroxybenzoates In Beverage. J Sep Sci. 2012 Jul;35(13):1667-74.
    [参考文献]: Fabrizio Carta, Et Al. Carbonic Anhydrase Inhibitors. Inhibition Of The β-Class Enzymes From The Fungal Pathogens Candida Albicans And Cryptococcus Neoformans With Branched Aliphatic/aromatic Carboxylates And Their Derivatives. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2521-6.
    [参考文献]: Lian Zhou, Et Al. The Rice Bacterial Pathogen Xanthomonas Oryzae Pv. Oryzae Produces 3-Hydroxybenzoic Acid And 4-Hydroxybenzoic Acid Via Xanb2 For Use In Xanthomonadin, Ubiquinone, And Exopolysaccharide Biosynthesis. Mol Plant Microbe Interact. 2013 Oct;26(10):1239-48.

    合成参考文献


    摘要:Journal of the American Pharmaceutical Association, Scientific Edition., 45(260), 1956
    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 39(S1):5-97,2020
    参考文献:10.1140/epje/i2014-14038-9
    摘要:Khimani M, Parekh P, Aswal VK, Bahadur P. Interaction, solubilization and location of p-hydroxybenzoic acid and its sodium salt in micelles of moderately hydrophilic PEO-PPO-PEO triblock copolymers. Eur Phys J E Soft Matter. 2014 May;37(5):38. doi: 10.1140/epje/i2014-14038-9.
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