CAS: 778576-62-8; N-(3,5-Dichloropyridin-4-yl)-4-(Difluoromethoxy)-8-(Methylsulfonamido)Dibenzo[b,D]Furan-1-Carboxamide

上下游产品

methanesulfonyl chloride 1-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-amino-dibenzo[b,d]furan-1-carboxamideN1-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-amino-dibenzo[b,d]furan-1-carboxamide

📜N1-(3,5-Dichloropyrid-4-yl)-4-Difluoromethoxy-8-Amino-Dibenzo[b,D]Furan-1-Carboxamide 反应生成 N-(3,5-二氯吡啶-4-基)-4-二氟甲氧基-8-[(甲磺酰基)氨基]二苯并[b,D]呋喃-1-甲酰胺
参考文献: Process For The Preparation Of N-(3,5-Dichloropyrid-4-yl)-4Difluoromethoxy-8-Methanesulfonamido-Dibenzo[b,D]Furan-1-Carboxamide[fr] Procede De Preparation De N-(3,5-Dichloropyrid-4-yl)-4-Difluoromethoxy-8-Methanesulfonamido-Dibenzo[b,D]Furan-1-Carboxamide
标题: Process For The Preparation Of N-(3,5-Dichloropyrid-4-yl)-4Difluoromethoxy-8-Methanesulfonamido-Dibenzo[b,D]Furan-1-Carboxamide[fr] Procede De Preparation De N-(3,5-Dichloropyrid-4-yl)-4-Difluoromethoxy-8-Methanesulfonamido-Dibenzo[b,D]Furan-1-Carboxamide
摘要:本发明涉及制备n-(3,5-二氯吡啶-4-基)-4-二氟甲氧基-8-甲磺酰基-二苯并[b,D]呋喃-1-羧酰胺及其药学上可接受的盐,如其钠盐,以及在合成上述化合物中有用的新的中间体化合物的方法.

专利信息

专利号:US-7511150-B2
优先权日:2006-07-06
标 题:Synthesis of heterocyclic compounds
发明人：ARALDI GIAN-LUCA; RONSHEIM MELANIE; DIEP NHUT; ZHOU SHAO HONG
权利人:FOREST LAB HOLDINGS LTD
摘要:Methods for the synthesis of heterocyclic compounds including N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide and pharmaceutically acceptable salts thereof.

专利号:US-9982006-B2
优先权日:2014-08-21
标题:2′-chloro aminopyrimidinone and pyrimidine dione nucleosides
发明人：CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
权利人:GILEAD SCIENCES INC
摘要:Provided herein are formulations, methods and substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds.

专利号:US-2008009632-A1
优先权日:2006-07-06
标 题:Synthesis of heterocyclic compounds

专利号:US-9751877-B2
优先权日:2012-09-21
标题 :Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; GREEN MICHAEL ERIC; PATEL NANDINI CHATURBHAI; STIFF CORY MICHAEL; TRAN TUAN PHONG; KAUFFMAN GREGORY WAYNE; STEPAN ANTONIA FRIEDERIKE; VERHOEST PATRICK ROBERT
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2009143593-A1
优先权日:2006-07-06
标 题:Synthesis of heterocyclic compounds

专利号:WO-2008065522-A3
优先权日:2006-11-29
标题 :Process for the synthesis of 4-difluoromethoxy-8-nitro-1-formyl dibenzo[b,d] furan-an intermediate for pde iv inhibitors
发明人：GHARAT LAXMIKANT ATMARAM; GAJERA JITENDRA MAGANBHAI; PATIL SANDIP DAMODAR
权利人:GLENMARK PHARMACEUTICALS SA; GHARAT LAXMIKANT ATMARAM; GAJERA JITENDRA MAGANBHAI; PATIL SANDIP DAMODAR
摘要:The present invention relates to a process for preparing 4-difluoromethoxy-8- nitro-1-formyl dibenzo[b,d]furan, which is useful as an intermediate for preparing compounds with PDE4 inhibitory activity. The invention further provides a process for preparing a PDE4 inhibitor, such as oglemilast.