CAS: 703-67-3; 6-Fluoro-1-Tetralone

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CAS号70631-88-8 4-(3-fluoro-phe... | CAS号69797-47-3 4-(3-fluoro-phe... | CAS号3470-50-6 6-羟基-1-萘满酮 | CAS号1078-19-9 6-甲氧基-1-萘满酮 | CAS号3470-53-9 6-氨基-3,4-二氢-1(2H)-萘酮 | CAS号62942-25-0 tributyl-(3-flu...

📜4-(4-氟苯基)丁酸置于polyphosphoric Acid体系中,化学反应生成 6-氟-3,4-二氢-2H-1-萘酮
参考文献:环状酰胺与手性磷酸促进的醌单亚胺的高对映选择性[3 + 2]偶联
标题:环状酰胺与手性磷酸促进的醌单亚胺的高对映选择性[3 + 2]偶联
摘要:使用手性磷酸作为催化剂,实现环酰胺与醌单亚胺的对映选择性[3 + 2]偶联.该转化允许合成高度对映体富集的多环2,3-二氢苯并呋喃.
DOI:10.1039/c6Cc01200K

专利信息

专利号:US-7479569-B2
优先权日:2004-02-13
标题:Process for the synthesis of (7-methoxy-3,4-dihydro-1-naphthalenyl) acetonitrile and its application in the synthesis of agomelatine
发明人：SOUVIE JEAN-CLAUDE; GONZALEZ BLANCO ISAAC
权利人:SERVIER LAB
摘要:A process for the industrial synthesis of the compound of formula (I) n nApplication in the synthesis of agomelatine.

专利号:US-7999129-B2
优先权日:2004-02-13
标 题:Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine
发明人：SOUVIE JEAN-CLAUDE; BLANCO ISAAC GONZALEZ
权利人:SERVIER LAB
摘要:A process for the industrial synthesis of the compound of formula (I) n nApplication in the synthesis of agomelatine.

专利号:US-9365494-B2
优先权日:2008-12-18
标 题 :Process for synthesis of amino-methyl tetralin derivatives
发明人：DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN
权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC
摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.

专利号:US-2005182267-A1
优先权日:2004-02-13
标题:Process for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and its application in the synthesis of agomelatine

专利号:US-7498465-B2
优先权日:2004-02-13
标 题 :Process for the synthesis and crystalline form of agomelatine
发明人：SOUVIE JEAN-CLAUDE; BLANCO ISAAC GONZALEZ; THOMINOT GILLES; CHAPUIS GENEVIEVE; HORVATH STEPHANE; DAMIEN GERARD
权利人:SERVIER LAB
摘要:A process for the industrial synthesis and new crystalline form of the compound of formula (I): n nMedicinal products containing the same which are useful in treating disorders of the melatoninergic system.

专利号:US-7476751-B2
优先权日:2004-02-13
标题:Process for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and its application in the synthesis of agomelatine