📜戊基beta-D-吡喃葡萄糖苷置于almond Meal体系中,用 水 作为反应溶剂,化学反应 336.0H,反应生成 己基β-D-吡喃葡萄糖苷 参考文献:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst 标题:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst 摘要:An Array Of Ten Beta-D-Glueopyranosides With Varied Alkyl Chain Lengths Were Enzymatically Synthesized. It Was Found That For Longer Alkyl Chains A Lower Initial Rate And Final Yield Of Glucoside Was Obtained Except For Methyl Glucoside Because Of The Severe Toxicity Of Methanol To The Enzyme. From A Thermodynamics Point Of View,The Equilibrium Constant And Gibbs Free Energy Variation Of The Glucoside Syntheses Were Systematically Investigated. To Improve The Final Yields Of The Glucosides Containing Long Alkyl Chains The Equilibrium Of The Enzymatic Glucoside Synthesis Was Altered. The Equilibrium Yield Of Decyl Beta-D-Glucoside Increased From 1.9% To 6.1% When The Water Content Was Reduced From 10% To 5% (V/v) Using Tert-Butanol As A Cosolvent And 0.10 Mol/l Of Glucose As A Substrate. As For The Other Longer Alkyl Chain Glucosides,Heptyl Beta-D-Glucoside Was Found To Have Significant Surface Activity As Well. DOI:10.1016/s1872-2067(11)60333-1
专利号:US-2006211083-A1 优先权日:2005-01-21 标题:Products and processes for in vitro synthesis of biomolecules 发明人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA 权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA 摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.
专利号:US-2001049117-A1 优先权日:1998-08-20 标 题 :Analogs of udp-murnac peptides, assays, kits and related methods of their use 发明人:AXELROD HELENA R; BRANSTROM ARTHUR A 摘要:General compositions and methods for detecting Lipid I, Lipid II and peptidoglycan synthesis is disclosed. A method of screening for potential antibacterial agents is provided which requires bacterial membrane preparations or enriched enzyme preparations including at least one bacterial enzyme involved in the synthesis of Lipid I from UDP-MurNAc pentapeptide and undecaprenyl phosphate, at least one bacterial enzyme involved in the synthesis of Lipid II from Lipid I and UDP-GlcNAc and one or more bacterial enzymes involved in the further processing of Lipid II toward the downstream synthesis of peptidoglycan. The methods disclosed herein further provides a labeled UDP-MurNAc-peptide capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid I and a labeled UDP-GlcNAc capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid II. Conditions for further processing of Lipid II toward the downstream synthesis of peptidoglycan are also discribed.
专利号:WO-2006078821-A2 优先权日:2005-01-21 标题:Products and processes for in vitro synthesis of biomolecules
专利号:US-2010055187-A1 优先权日:2008-08-28 标题:Nanovitamin synthesis 发明人:AHN DONG JUNE 权利人:AHN DONG JUNE 摘要:Stable nanoparticulate vitamin compositions are prepared from agglomerated or larger sized vitamin particles of at least one vitamin compound by breaking down and/or solubilizing the agglomerated or larger sized vitamin particles and associating the particles with a surface modifying agent.
专利号:US-2009028948-A1 优先权日:2004-12-31 标 题 :Nanoparticle composition and methods of synthesis thereof
专利号:CN-111363770-A 优先权日:2020-05-07 标题:A kind of synthesis technology of surfactant hexyl glycoside
参考文献:10.1248/cpb.56.536 摘要:Nakamura S, Li X, Matsuda H, Yoshikawa M. Bioactive constituents from Chinese natural medicines. XXVIII. Chemical structures of acyclic alcohol glycosides from the roots of Rhodiola crenulata. Chem Pharm Bull (Tokyo). 2008 Apr;56(4):536–40. doi: 10.1248/cpb.56.536. 参考文献:10.1021/bi049106n 摘要:Raja MM, Kipp H, Kinne RK. C-terminus loop 13 of Na+ glucose cotransporter SGLT1 contains a binding site for alkyl glucosides. Biochemistry. 2004 Aug 31;43(34):10944–51. doi: 10.1021/bi049106n.